iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
WBGene00018319	F41H10.6a	F41H10.6a
WBGene00018319	F41H10.6b	F41H10.6b
WBGene00018319	F41H10.6c	F41H10.6c

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	38.46	5.00e-144	509.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Caenorhabditis elegans

Functional Description
(View)

Probable histone deacetylase. Histone deacetylases are responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).

Protein Sequence
(Fasta)

MLFEDRQKNR STGPTLIGFN QTQNEHENTV CPTHPESSDR ILKIKEALTK TKILEKCTVL 60
TNFLEIDDAD LEVTHDKSMV KDLMESEKKT QEDINSQCEK YDSVFMTENS MKVAKDGVAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTAGACT TTTAGCGGTT ATTCAAACAT TTATCGTTTA GTTTTCCATG CTTTTCGAAG 60
ATAGGCAGAA AAATCGATCA ACGGTAAGAA AAGTATATGT TCGTACAATC ATATAATCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558--F:protein deacetylase activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

cel:CELE_F41H10.6

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	43.49	5.00e-60	224.00
IUUC-Aml-002087	Ailuropoda melanoleuca	37.25	1.00e-148	520.00
IUUC-Atr-002745	Amborella trichopoda	38.75	5.00e-71	260.00
IUUC-Apl-003250	Anas platyrhynchos	38.44	8.00e-68	251.00
IUUC-Aca-004303	Anolis carolinensis	38.12	1.00e-156	546.00
IUUC-Aly-006432	Arabidopsis lyrata	38.21	5.00e-73	267.00
IUUC-Ath-007355	Arabidopsis thaliana	39.47	2.00e-74	272.00
IUUC-Ago-007972	Ashbya gossypii	41.21	4.00e-76	277.00
IUUC-Acl-008187	Aspergillus clavatus	37.65	1.00e-74	273.00
IUUC-Afl-008399	Aspergillus flavus	44.44	3.00e-44	171.00
IUUC-Afu-008954	Aspergillus fumigatus	37.60	1.00e-62	232.00
IUUC-Ani-009142	Aspergillus nidulans	40.98	5.00e-68	251.00
IUUC-Ang-009522	Aspergillus niger	36.93	7.00e-22	97.80
IUUC-Aor-010069	Aspergillus oryzae	39.06	2.00e-67	248.00
IUUC-Ate-010291	Aspergillus terreus	39.01	6.00e-76	277.00
IUUC-Ame-010780	Astyanax mexicanus	35.67	4.00e-125	441.00
IUUC-Bta-013052	Bos taurus	37.42	6.00e-141	494.00
IUUC-Bci-013789	Botrytis cinerea	38.56	3.00e-68	251.00
IUUC-Bdi-014007	Brachypodium distachyon	42.22	2.00e-71	262.00
IUUC-Bol-015468	Brassica oleracea	40.32	7.00e-75	273.00
IUUC-Bra-016680	Brassica rapa	40.32	7.00e-75	273.00
IUUC-Cja-019473	Callithrix jacchus	38.39	2.00e-142	499.00
IUUC-Cfa-020263	Canis familiaris	37.93	3.00e-147	515.00
IUUC-Cpo-021691	Cavia porcellus	37.79	4.00e-150	524.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	45.79	3.00e-49	186.00
IUUC-Csa-024223	Chlorocebus sabaeus	37.78	6.00e-148	517.00
IUUC-Cho-025033	Choloepus hoffmanni	30.99	1.00e-02	34.70
IUUC-Csv-026359	Ciona savignyi	40.71	8.00e-56	209.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	38.16	8.00e-65	240.00
IUUC-Cne-026978	Cryptococcus neoformans	44.86	1.00e-83	303.00
IUUC-Dre-028820	Danio rerio	38.90	2.00e-150	525.00
IUUC-Dno-029160	Dasypus novemcinctus	36.42	6.00e-122	431.00
IUUC-Dor-030859	Dipodomys ordii	39.48	6.00e-153	533.00
IUUC-Dse-031186	Dothistroma septosporum	38.50	6.00e-66	244.00
IUUC-Dme-031963	Drosophila melanogaster	38.98	2.00e-155	542.00
IUUC-Ete-032279	Echinops telfairi	37.69	1.00e-60	227.00
IUUC-Eca-033842	Equus caballus	38.19	1.00e-151	530.00
IUUC-Eeu-034487	Erinaceus europaeus	47.39	5.00e-62	231.00
IUUC-Fca-036430	Felis catus	42.06	9.00e-83	300.00
IUUC-Fox-038067	Fusarium oxysporum	37.57	1.00e-61	229.00
IUUC-Fso-038263	Fusarium solani	38.10	5.00e-66	244.00
IUUC-Gmo-038473	Gadus morhua	45.82	1.00e-64	240.00
IUUC-Ggr-040062	Gaeumannomyces graminis	37.67	2.00e-65	242.00
IUUC-Gga-040501	Gallus gallus	38.44	9.00e-68	250.00
IUUC-Gac-042335	Gasterosteus aculeatus	39.84	2.00e-67	249.00
IUUC-Gma-043738	Glycine max	36.31	2.00e-68	251.00
IUUC-Ggo-045022	Gorilla gorilla	38.09	2.00e-148	519.00
IUUC-Hsa-046904	Homo sapiens	38.09	2.00e-148	519.00
IUUC-Hvu-047285	Hordeum vulgare	41.90	4.00e-70	256.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	37.52	3.00e-149	521.00
IUUC-Kpa-049281	Komagataella pastoris	39.67	1.00e-70	259.00
IUUC-Lch-050330	Latimeria chalumnae	37.62	7.00e-120	424.00
IUUC-Lpe-051214	Leersia perrieri	37.77	5.00e-72	264.00
IUUC-Loc-052231	Lepisosteus oculatus	38.62	9.00e-67	247.00
IUUC-Lma-053263	Leptosphaeria maculans	41.48	6.00e-74	271.00
IUUC-Laf-053386	Loxodonta africana	38.32	5.00e-147	514.00
IUUC-Mcc-055530	Macaca mulatta	37.97	2.00e-147	515.00
IUUC-Meu-056442	Macropus eugenii	41.60	1.00e-80	292.00
IUUC-Mor-057095	Magnaporthe oryzae	40.48	1.00e-71	263.00
IUUC-Mpo-057389	Magnaporthe poae	40.67	1.00e-62	233.00
IUUC-Mtr-058463	Medicago truncatula	42.49	9.00e-75	273.00
IUUC-Mla-059143	Melampsora laricipopulina	37.24	2.00e-74	272.00
IUUC-Mmr-060637	Microcebus murinus	37.80	9.00e-143	500.00
IUUC-Mdo-062198	Monodelphis domestica	39.92	1.00e-153	535.00
IUUC-Mmu-063346	Mus musculus	40.18	9.00e-156	543.00
IUUC-Mac-064630	Musa acuminata	38.02	6.00e-73	267.00
IUUC-Mpu-065884	Mustela putorius furo	36.87	4.00e-148	518.00
IUUC-Mlu-068117	Myotis lucifugus	39.61	8.00e-142	496.00
IUUC-Nfi-068404	Neosartorya fischeri	39.78	1.00e-72	266.00
IUUC-Ncr-068672	Neurospora crassa	36.10	1.00e-65	243.00
IUUC-Nle-069868	Nomascus leucogenys	43.97	4.00e-73	268.00
IUUC-Opr-071074	Ochotona princeps	42.09	2.00e-84	305.00
IUUC-Ont-072246	Oreochromis niloticus	39.27	4.00e-150	524.00
IUUC-Oan-072911	Ornithorhynchus anatinus	42.09	4.00e-58	218.00
IUUC-Ocu-074627	Oryctolagus cuniculus	38.42	4.00e-153	534.00
IUUC-Oba-075489	Oryza barthii	40.56	8.00e-71	260.00
IUUC-Obr-076150	Oryza brachyantha	41.80	1.00e-73	269.00
IUUC-Ogl-077437	Oryza glaberrima	37.77	1.00e-71	263.00
IUUC-Ogu-078370	Oryza glumaepatula	38.04	2.00e-72	265.00
IUUC-Oin-079210	Oryza indica	38.32	2.00e-72	266.00
IUUC-Olo-080971	Oryza longistaminata	44.73	2.00e-65	242.00
IUUC-Oni-082031	Oryza nivara	38.32	2.00e-72	265.00
IUUC-Opu-083471	Oryza punctata	40.25	8.00e-71	260.00
IUUC-Oru-084755	Oryza rufipogon	38.04	2.00e-72	265.00
IUUC-Osa-085447	Oryza sativa	38.04	2.00e-72	265.00
IUUC-Ola-087031	Oryzias latipes	40.32	3.00e-69	256.00
IUUC-Oga-089155	Otolemur garnettii	37.92	7.00e-149	520.00
IUUC-Oar-089620	Ovis aries	36.44	4.00e-141	494.00
IUUC-Ptr-090812	Pan troglodytes	37.37	6.00e-121	426.00
IUUC-Pan-092340	Papio anubis	37.97	2.00e-147	515.00
IUUC-Psi-093734	Pelodiscus sinensis	38.22	1.00e-67	250.00
IUUC-Pma-094386	Petromyzon marinus	39.16	6.00e-135	474.00
IUUC-Pno-095131	Phaeosphaeria nodorum	44.84	4.00e-67	247.00
IUUC-Ppa-095550	Physcomitrella patens	38.81	8.00e-70	257.00
IUUC-Pfo-096110	Poecilia formosa	41.16	8.00e-140	489.00
IUUC-Pab-098422	Pongo abelii	37.45	4.00e-138	484.00
IUUC-Pop-099174	Populus trichocarpa	38.96	2.00e-73	268.00
IUUC-Pca-100833	Procavia capensis	37.58	1.00e-149	522.00
IUUC-Ppe-101644	Prunus persica	35.54	1.00e-68	253.00
IUUC-Pva-102410	Pteropus vampyrus	38.20	4.00e-114	404.00
IUUC-Ptt-103841	Puccinia triticina	35.15	4.00e-66	244.00
IUUC-Pte-104383	Pyrenophora teres	40.17	5.00e-72	264.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	41.00	2.00e-73	268.00
IUUC-Rno-105131	Rattus norvegicus	39.50	2.00e-155	542.00
IUUC-Sce-106274	Saccharomyces cerevisiae	40.77	2.00e-71	262.00
IUUC-Sha-106661	Sarcophilus harrisii	33.33	4.00e-100	358.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	40.37	3.00e-78	285.00
IUUC-Spo-108300	Schizosaccharomyces pombe	40.16	2.00e-75	275.00
IUUC-Smo-109615	Selaginella moellendorffii	41.16	4.00e-73	268.00
IUUC-Sit-110160	Setaria italica	40.17	5.00e-66	244.00
IUUC-Sly-111164	Solanum lycopersicum	39.94	1.00e-75	276.00
IUUC-Stu-112685	Solanum tuberosum	36.56	1.00e-65	242.00
IUUC-Sar-113692	Sorex araneus	39.74	2.00e-59	223.00
IUUC-Sbi-114301	Sorghum bicolor	40.62	8.00e-66	243.00
IUUC-Sre-115013	Sporisorium reilianum	40.11	5.00e-72	264.00
IUUC-Ssc-115724	Sus scrofa	39.33	9.00e-137	479.00
IUUC-Tgu-116605	Taeniopygia guttata	43.34	3.00e-69	255.00
IUUC-Tru-117614	Takifugu rubripes	40.93	5.00e-160	557.00
IUUC-Tsy-118807	Tarsius syrichta	33.82	4.00e-78	285.00
IUUC-Tni-119809	Tetraodon nigroviridis	42.13	5.00e-153	534.00
IUUC-Tca-121312	Theobroma cacao	38.03	1.00e-71	263.00
IUUC-Tre-121930	Trichoderma reesei	39.52	1.00e-66	246.00
IUUC-Tvi-122373	Trichoderma virens	39.79	5.00e-65	241.00
IUUC-Tae-123064	Triticum aestivum	37.25	1.00e-63	235.00
IUUC-Tme-127027	Tuber melanosporum	37.16	2.00e-60	225.00
IUUC-Tbe-127675	Tupaia belangeri	38.61	2.00e-19	90.50
IUUC-Ttr-128411	Tursiops truncatus	34.79	8.00e-141	493.00
IUUC-Uma-129408	Ustilago maydis	45.33	7.00e-68	250.00
IUUC-Vda-129994	Verticillium dahliae	37.67	4.00e-66	244.00
IUUC-Vpa-130525	Vicugna pacos	64.29	8.00e-19	87.80
IUUC-Vvi-131038	Vitis vinifera	40.19	5.00e-71	260.00
IUUC-Xtr-132618	Xenopus tropicalis	39.45	9.00e-160	556.00
IUUC-Xma-133730	Xiphophorus maculatus	36.49	3.00e-126	445.00
IUUC-Yli-134680	Yarrowia lipolytica	39.19	2.00e-72	266.00
IUUC-Zma-135110	Zea mays	40.56	1.00e-65	243.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence