iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133740

Ensembl Protein ID

ENSXMAP00000005300.1

UniProt Accession

M3ZSV7; M3ZSV7_XIPMA

Genbank Protein ID

ENSXMAP00000005300

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGAJ01015532

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000005279.1	ENSXMAT00000005306.1	ENSXMAP00000005300.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-14	52.9	76	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 76   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 133
           68899************************.***********..79999**********997 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MGQQPGKFVG DQRRPSLPAF IKGGKRDSSR HVSQPWNVFD RHEALQRPDF EGQGLSEAAR 60
WNSKENLLAG PSENDPNLFV ALYDFVASGD NTLSITKGEK LRVLGYNHNG EWCEAQTKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGC AGCCGGGGAA ATTTGTAGGG GACCAGAGGA GACCCAGTTT GCCAGCTTTC 60
ATCAAGGGGG GAAAGAGAGA CTCATCACGC CATGTGAGCC AGCCATGGAA TGTTTTCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	70.64	0.00e+00	1127.00
IUUC-Apl-003452	Anas platyrhynchos	86.26	0.00e+00	1013.00
IUUC-Aca-005312	Anolis carolinensis	71.26	0.00e+00	1081.00
IUUC-Ame-011903	Astyanax mexicanus	77.64	0.00e+00	1207.00
IUUC-Bta-012351	Bos taurus	71.28	0.00e+00	1078.00
IUUC-Cja-019491	Callithrix jacchus	64.57	0.00e+00	1258.00
IUUC-Cfa-021256	Canis familiaris	76.15	0.00e+00	1139.00
IUUC-Cpo-022046	Cavia porcellus	75.91	0.00e+00	1137.00
IUUC-Csa-023046	Chlorocebus sabaeus	71.56	0.00e+00	1079.00
IUUC-Dre-028190	Danio rerio	68.76	0.00e+00	1289.00
IUUC-Dno-029853	Dasypus novemcinctus	86.15	0.00e+00	1075.00
IUUC-Dor-030635	Dipodomys ordii	66.90	0.00e+00	978.00
IUUC-Dme-032098	Drosophila melanogaster	74.03	0.00e+00	761.00
IUUC-Eca-033720	Equus caballus	71.49	0.00e+00	1082.00
IUUC-Eeu-035173	Erinaceus europaeus	80.30	0.00e+00	1006.00
IUUC-Fca-035967	Felis catus	86.29	0.00e+00	1072.00
IUUC-Fal-036723	Ficedula albicollis	70.44	0.00e+00	1061.00
IUUC-Gmo-039550	Gadus morhua	81.36	0.00e+00	1222.00
IUUC-Gga-040481	Gallus gallus	75.97	0.00e+00	1059.00
IUUC-Gac-041643	Gasterosteus aculeatus	80.28	0.00e+00	1642.00
IUUC-Gma-043854	Glycine max	29.71	3.00e-21	97.40
IUUC-Ggo-045299	Gorilla gorilla	71.21	0.00e+00	1126.00
IUUC-Hsa-047033	Homo sapiens	89.74	1.00e-37	147.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	85.46	0.00e+00	1045.00
IUUC-Lch-050530	Latimeria chalumnae	71.04	0.00e+00	1141.00
IUUC-Loc-052430	Lepisosteus oculatus	83.77	0.00e+00	992.00
IUUC-Laf-053609	Loxodonta africana	86.44	0.00e+00	1077.00
IUUC-Mcc-055654	Macaca mulatta	65.88	0.00e+00	1268.00
IUUC-Meu-056488	Macropus eugenii	58.23	0.00e+00	1057.00
IUUC-Mga-059270	Meleagris gallopavo	74.87	0.00e+00	1066.00
IUUC-Mmr-060593	Microcebus murinus	74.32	0.00e+00	1075.00
IUUC-Mdo-062227	Monodelphis domestica	85.21	0.00e+00	1067.00
IUUC-Mmu-064002	Mus musculus	71.79	0.00e+00	1160.00
IUUC-Mpu-066197	Mustela putorius furo	72.30	0.00e+00	1115.00
IUUC-Mlu-067255	Myotis lucifugus	70.67	0.00e+00	1059.00
IUUC-Nle-069977	Nomascus leucogenys	69.63	0.00e+00	994.00
IUUC-Opr-070327	Ochotona princeps	67.80	0.00e+00	920.00
IUUC-Ont-072307	Oreochromis niloticus	77.92	0.00e+00	1601.00
IUUC-Oan-073100	Ornithorhynchus anatinus	70.80	0.00e+00	1080.00
IUUC-Ocu-074892	Oryctolagus cuniculus	71.83	0.00e+00	977.00
IUUC-Ola-087389	Oryzias latipes	75.77	0.00e+00	1550.00
IUUC-Oga-088145	Otolemur garnettii	87.42	0.00e+00	1021.00
IUUC-Oar-090432	Ovis aries	73.37	0.00e+00	1062.00
IUUC-Ptr-090800	Pan troglodytes	71.43	0.00e+00	1129.00
IUUC-Psi-093078	Pelodiscus sinensis	65.85	0.00e+00	1236.00
IUUC-Pma-094420	Petromyzon marinus	75.80	0.00e+00	862.00
IUUC-Pfo-096979	Poecilia formosa	96.29	0.00e+00	1845.00
IUUC-Pca-100874	Procavia capensis	93.42	0.00e+00	704.00
IUUC-Pva-102415	Pteropus vampyrus	72.05	0.00e+00	1115.00
IUUC-Rno-105682	Rattus norvegicus	71.97	0.00e+00	1159.00
IUUC-Sha-106711	Sarcophilus harrisii	71.62	0.00e+00	1094.00
IUUC-Ssc-115472	Sus scrofa	75.79	0.00e+00	1125.00
IUUC-Tgu-117037	Taeniopygia guttata	75.06	0.00e+00	1127.00
IUUC-Tru-118324	Takifugu rubripes	70.74	0.00e+00	1429.00
IUUC-Tsy-119216	Tarsius syrichta	90.72	0.00e+00	1025.00
IUUC-Tni-119950	Tetraodon nigroviridis	71.90	0.00e+00	1429.00
IUUC-Ttr-128209	Tursiops truncatus	65.99	0.00e+00	1279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence