iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000034175.13	ENSMUST00000101610.9	ENSMUSP00000099131.3
ENSMUSG00000034175.13	ENSMUST00000036320.11	ENSMUSP00000044703.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	24859449

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UBA	0.00087	20.5	328	361

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 7    leqlveMGFdreealqaLraannnleaAveyLldg 41
           l+ql+ MGF++e+a  aL+a  + +e Av +L +g
   Q: 328  LQQLQHMGFPTEQAAVALAA-TGRVEGAVSLLVEG 361
           9*******************.7********99875 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MHAWEAPGSL SRALPLASSV LMLLLSCLWL LGAGPSLRLA PELLMEPWQV HRLLTHALGH 60
TALPGLLLSL LLLPTLGWWQ ECHLGTVRFL HNSTVLALAT GLLAVLLAGL GVSGAAGGCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCTGCCAC CCCCAGAGAC GAGCGCCTCC CAGTCTGGGT GTCCCAGCTG TCGCCGGCGG 60
GACCGCGATC CCACTCCGCT TACCCGTGGA CGCCATTTTC TCGCCTTCCT CCTCGTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR022764--Peptidase_S54_rhomboid_dom
IPR015940--UBA
IPR009060--UBA-like

Pfam

PF01694--Rhomboid
PF00627--UBA

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0004252--F:serine-type endopeptidase activity
GO:0001889--P:liver development
GO:0000165--P:MAPK cascade
GO:0032815--P:negative regulation of natural killer cell activation
GO:0045732--P:positive regulation of protein catabolic process
GO:0002673--P:regulation of acute inflammatory response
GO:0050708--P:regulation of protein secretion
GO:0009410--P:response to xenobiotic stimulus

KEGG

mmu:279766

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001619	Ailuropoda melanoleuca	77.22	3.00e-70	258.00
IUUC-Aca-004494	Anolis carolinensis	40.56	6.00e-27	115.00
IUUC-Ame-010805	Astyanax mexicanus	52.87	6.00e-18	85.10
IUUC-Bta-012844	Bos taurus	75.66	4.00e-58	218.00
IUUC-Bol-016202	Brassica oleracea	23.17	3.70e-02	31.60
IUUC-Bra-017006	Brassica rapa	22.89	1.00e-02	33.50
IUUC-Cja-019853	Callithrix jacchus	76.77	5.00e-81	294.00
IUUC-Cfa-021026	Canis familiaris	76.63	3.00e-88	318.00
IUUC-Csa-023360	Chlorocebus sabaeus	77.62	1.00e-88	319.00
IUUC-Dre-027575	Danio rerio	34.33	2.00e-18	86.30
IUUC-Dno-029113	Dasypus novemcinctus	72.86	2.00e-62	233.00
IUUC-Dor-030646	Dipodomys ordii	76.97	9.00e-96	343.00
IUUC-Eca-034158	Equus caballus	75.85	2.00e-87	315.00
IUUC-Eeu-034983	Erinaceus europaeus	61.17	3.00e-51	194.00
IUUC-Fca-035531	Felis catus	77.42	1.00e-95	343.00
IUUC-Ggo-045015	Gorilla gorilla	76.20	8.00e-82	297.00
IUUC-Hsa-046646	Homo sapiens	76.49	4.00e-84	304.00
IUUC-Itr-048164	Ictidomys tridecemlineatus	77.02	8.00e-98	350.00
IUUC-Lch-049560	Latimeria chalumnae	34.45	2.00e-15	76.60
IUUC-Loc-052194	Lepisosteus oculatus	36.39	2.00e-03	36.60
IUUC-Laf-054308	Loxodonta africana	73.94	1.00e-77	283.00
IUUC-Mcc-055034	Macaca mulatta	68.56	7.00e-67	247.00
IUUC-Meu-056317	Macropus eugenii	49.16	1.00e-32	133.00
IUUC-Mmr-061591	Microcebus murinus	74.31	9.00e-60	223.00
IUUC-Mdo-062745	Monodelphis domestica	51.09	9.00e-41	160.00
IUUC-Mac-065073	Musa acuminata	50.00	1.10e-01	32.00
IUUC-Mpu-066394	Mustela putorius furo	76.70	2.00e-85	309.00
IUUC-Mlu-067595	Myotis lucifugus	72.73	3.00e-81	295.00
IUUC-Nle-069211	Nomascus leucogenys	75.57	1.00e-86	313.00
IUUC-Opr-070249	Ochotona princeps	66.18	5.00e-69	253.00
IUUC-Oan-073402	Ornithorhynchus anatinus	58.76	5.00e-05	40.40
IUUC-Ocu-074418	Oryctolagus cuniculus	74.21	1.00e-83	303.00
IUUC-Ogl-077238	Oryza glaberrima	26.42	3.60e-01	30.00
IUUC-Olo-080578	Oryza longistaminata	26.42	5.90e-01	30.00
IUUC-Oni-082791	Oryza nivara	34.62	3.60e-01	29.60
IUUC-Opu-083378	Oryza punctata	28.30	1.90e-01	31.60
IUUC-Ola-087450	Oryzias latipes	49.41	5.00e-16	77.40
IUUC-Oga-088214	Otolemur garnettii	76.29	1.00e-95	343.00
IUUC-Oar-089324	Ovis aries	69.20	2.00e-31	129.00
IUUC-Ptr-091322	Pan troglodytes	71.82	6.00e-61	226.00
IUUC-Pan-092490	Papio anubis	76.20	6.00e-94	337.00
IUUC-Pfo-097125	Poecilia formosa	52.00	2.00e-14	72.80
IUUC-Pab-097546	Pongo abelii	81.12	3.00e-30	125.00
IUUC-Pva-102615	Pteropus vampyrus	75.07	3.00e-90	325.00
IUUC-Rno-105844	Rattus norvegicus	91.43	2.00e-131	462.00
IUUC-Sha-107118	Sarcophilus harrisii	48.90	1.00e-26	113.00
IUUC-Ssc-115786	Sus scrofa	76.04	2.00e-87	315.00
IUUC-Tre-122096	Trichoderma reesei	40.00	2.70e-01	29.30
IUUC-Ttr-128407	Tursiops truncatus	72.43	1.00e-80	293.00
IUUC-Xtr-131878	Xenopus tropicalis	32.44	3.00e-16	79.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence