iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042362

Ensembl Protein ID

ENSGACP00000004798.1

UniProt Accession

G3NHI9; G3NHI9_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000003658.1	ENSGACT00000004812.1	ENSGACP00000004798.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.20e-15	55.6	64	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +lydyea ++++L +kkGd+++++   +++++W+k++   +g++G++P+n+v+k
   Q: 64   MALYDYEAIHEGDLGFKKGDKLRIL---TESGEWWKAKLISSGQEGFIPSNYVAK 115
           69***********************...99***********************86 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCVGSKKEQ EPMGKGTDDG DQQSHTLTTH YVKDPTVGIP GSKPVSSSGS VVLGQGAVGE 60
SIAMALYDYE AIHEGDLGFK KGDKLRILTE SGEWWKAKLI SSGQEGFIPS NYVAKDTLEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGTG TGGGCTCGAA GAAGGAGCAG GAGCCTATGG GCAAAGGGAC GGACGACGGC 60
GACCAGCAGA GCCACACACT GACCACCCAC TACGTCAAAG ACCCTACCGT AGGAATCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	73.78	0.00e+00	776.00
IUUC-Apl-003285	Anas platyrhynchos	73.39	0.00e+00	780.00
IUUC-Aca-004724	Anolis carolinensis	75.10	0.00e+00	776.00
IUUC-Ame-011954	Astyanax mexicanus	83.79	0.00e+00	856.00
IUUC-Bta-013060	Bos taurus	74.21	0.00e+00	782.00
IUUC-Cja-019817	Callithrix jacchus	74.61	0.00e+00	785.00
IUUC-Cfa-020511	Canis familiaris	74.56	0.00e+00	784.00
IUUC-Cpo-022538	Cavia porcellus	74.26	0.00e+00	778.00
IUUC-Csa-024143	Chlorocebus sabaeus	74.75	0.00e+00	788.00
IUUC-Dre-028157	Danio rerio	83.79	0.00e+00	892.00
IUUC-Dno-029761	Dasypus novemcinctus	73.87	0.00e+00	788.00
IUUC-Eca-034090	Equus caballus	73.82	0.00e+00	760.00
IUUC-Fca-035937	Felis catus	73.43	0.00e+00	753.00
IUUC-Fal-036624	Ficedula albicollis	74.85	0.00e+00	801.00
IUUC-Gmo-039009	Gadus morhua	79.64	0.00e+00	837.00
IUUC-Gga-040296	Gallus gallus	71.76	0.00e+00	772.00
IUUC-Ggo-044570	Gorilla gorilla	73.92	0.00e+00	787.00
IUUC-Hsa-046378	Homo sapiens	74.12	0.00e+00	791.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	72.44	0.00e+00	772.00
IUUC-Loc-052904	Lepisosteus oculatus	81.66	0.00e+00	871.00
IUUC-Laf-053654	Loxodonta africana	73.87	0.00e+00	784.00
IUUC-Mcc-055317	Macaca mulatta	74.95	0.00e+00	794.00
IUUC-Mga-060194	Meleagris gallopavo	76.12	0.00e+00	736.00
IUUC-Mmr-061510	Microcebus murinus	73.62	0.00e+00	774.00
IUUC-Mdo-062035	Monodelphis domestica	73.23	0.00e+00	778.00
IUUC-Mmu-064037	Mus musculus	72.35	0.00e+00	776.00
IUUC-Mpu-066874	Mustela putorius furo	74.26	0.00e+00	781.00
IUUC-Mlu-068202	Myotis lucifugus	71.71	0.00e+00	753.00
IUUC-Nle-069222	Nomascus leucogenys	74.95	0.00e+00	789.00
IUUC-Opr-070705	Ochotona princeps	74.31	0.00e+00	780.00
IUUC-Ont-072347	Oreochromis niloticus	93.51	0.00e+00	859.00
IUUC-Ocu-074490	Oryctolagus cuniculus	73.96	0.00e+00	780.00
IUUC-Ola-086521	Oryzias latipes	92.22	0.00e+00	880.00
IUUC-Oga-088153	Otolemur garnettii	81.03	0.00e+00	782.00
IUUC-Oar-090184	Ovis aries	73.39	0.00e+00	773.00
IUUC-Ptr-090505	Pan troglodytes	70.39	0.00e+00	736.00
IUUC-Pan-092260	Papio anubis	74.95	0.00e+00	794.00
IUUC-Pma-094311	Petromyzon marinus	65.30	0.00e+00	699.00
IUUC-Pfo-096566	Poecilia formosa	85.01	0.00e+00	906.00
IUUC-Pva-103021	Pteropus vampyrus	75.29	0.00e+00	789.00
IUUC-Rno-105309	Rattus norvegicus	72.94	0.00e+00	780.00
IUUC-Sha-107099	Sarcophilus harrisii	73.39	0.00e+00	778.00
IUUC-Tgu-116912	Taeniopygia guttata	74.41	0.00e+00	791.00
IUUC-Tru-118449	Takifugu rubripes	88.59	0.00e+00	836.00
IUUC-Tbe-128144	Tupaia belangeri	72.65	0.00e+00	681.00
IUUC-Ttr-128457	Tursiops truncatus	68.15	0.00e+00	654.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence