iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001228.4	ENSCAFT00000001907.4	ENSCAFP00000001758.3
ENSCAFG00000001228.4	ENSCAFT00000045939.1	ENSCAFP00000037139.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-06	27.1	1029	1067

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.....sd.tllvsGsdDgtikvWDlrtgvl 35
           H +svt+l       ++   + s+s Dgt+  W+++t ++
   Q: 1029 HRSSVTDL-VaqngtPStSKVYSCSADGTVLAWNVSTLRV 1067
           99999998.33677855488**************998765 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

AQRKGVGGPP LEPEVLSVFV PPFVTKEDSQ TASAPCATLS KTRRRSFRKK RDKPKSEPWK 60
GLPPEDVTVP NGVDLLALPQ LCFPGGLCVA SEPKEDCVHF LVLTDVCGNR TYGVVAQYYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCAGCGGA AGGGGGTGGG CGGCCCTCCT CTCGAACCGG AGGTTCTGTC CGTGTTTGTG 60
CCTCCCTTCG TCACTAAGGA GGACAGTCAA ACGGCCAGCG CCCCCTGTGC CACCCTGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR005112--dDENN_dom
IPR001194--DENN_dom
IPR005113--uDENN_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50947--DDENN
PS50211--DENN
PS50946--UDENN
PS00678--WD_REPEATS_1

Pfam

PF02141--DENN
PF03456--uDENN

SMART

SM00801--dDENN
SM00799--DENN
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0044257--P:cellular protein catabolic process
GO:0008333--P:endosome to lysosome transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002428	Ailuropoda melanoleuca	89.85	0.00e+00	2227.00
IUUC-Ame-011614	Astyanax mexicanus	53.71	0.00e+00	1331.00
IUUC-Dor-030471	Dipodomys ordii	80.51	0.00e+00	1040.00
IUUC-Gmo-039067	Gadus morhua	52.79	4.00e-110	392.00
IUUC-Gac-041903	Gasterosteus aculeatus	52.46	0.00e+00	1250.00
IUUC-Hsa-046572	Homo sapiens	78.53	0.00e+00	1829.00
IUUC-Loc-052634	Lepisosteus oculatus	57.68	0.00e+00	1484.00
IUUC-Mcc-055358	Macaca mulatta	80.11	0.00e+00	1929.00
IUUC-Mmr-060775	Microcebus murinus	80.43	0.00e+00	2036.00
IUUC-Mmu-063704	Mus musculus	78.19	0.00e+00	1937.00
IUUC-Ont-072676	Oreochromis niloticus	51.74	0.00e+00	1273.00
IUUC-Oni-082213	Oryza nivara	25.51	5.00e-18	87.00
IUUC-Olu-087744	Ostreococcus lucimarinus	30.41	2.00e-12	68.60
IUUC-Oga-088682	Otolemur garnettii	80.08	0.00e+00	1993.00
IUUC-Ptr-090684	Pan troglodytes	78.87	0.00e+00	1822.00
IUUC-Pan-092645	Papio anubis	80.46	0.00e+00	1937.00
IUUC-Pfo-096475	Poecilia formosa	52.78	0.00e+00	1263.00
IUUC-Rno-105167	Rattus norvegicus	78.51	0.00e+00	1896.00
IUUC-Ssc-115459	Sus scrofa	73.79	6.00e-105	373.00
IUUC-Tru-118373	Takifugu rubripes	29.17	7.00e-16	80.10
IUUC-Tni-119750	Tetraodon nigroviridis	28.75	2.00e-15	78.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence