iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041879

UUCD1 version

UUC-GaA-00079

Ensembl Protein ID

ENSGACP00000002158.1

UniProt Accession

G3NA16; G3NA16_GASAC

Protein Name

Uncharacterized protein

Gene Name

HERC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000001653.1	ENSGACT00000002164.1	ENSGACP00000002158.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.80e-67	227.1	284	565

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrl.lgkalqdgrlld 89
           ++++v+fvgE++ d+gG  +e +a++++elqn+ ++l+  ++n++ +   n+d +l np      h+++F+flGr+ lg+a+++g +l 
   Q: 284  RVWKVKFVGESVDDCGGGYSESIAEMCEELQNALTPLLIVTPNGRDESGANRDCFLLNPaakspLHMSMFRFLGRVlLGIAIRTGSPLS 372
           4566****************************************9999*******999999999**********9637*********** PP
   S: 90   lplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           l+l+++++k+l g +l++ dl+evd++++  l++i++n+    e ++++l f+     +++++ +++  +++  ++t eN+ eYv+l +
   Q: 373  LNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEAPAEEFEAMTLPFT-----VPNASGQDIQLSSKYSHITLENRAEYVRLAI 456
           **************************************988888888999998.....7889999999********************* PP
   S: 179  eyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqF 267
           +yrl+e ++eqv a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++s+ iqwFwev+e+fs++er+ fL+F
   Q: 457  NYRLHE-FDEQVSAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-VEPTSSLIQWFWEVMESFSNTERSLFLRF 543
           ******.**************************************************77.***************************** PP
   S: 268  vTgssrlPlgGfaelkprlfvir 290
           v+g+ rlP + +a+++ r fv++
   Q: 544  VWGRTRLP-RTIADFRGRDFVVQ 565
           ********.78888888888875 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

WGDGDYGKLG RGGSDGCKIP MKIDSLTGLG VVKVECGSQF SVSLTKSGAV YTWGKGDYHR 60
LGHGSDDHVR RPRQVQGLQG KKVIAIATGS LHCVCCTEDG EVYTWGDNDE GQLGDGTTNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGGGGACG GGGACTACGG CAAACTGGGC CGCGGAGGAA GTGACGGCTG TAAAATCCCC 60
ATGAAGGTGA GTCAGTTCAA CAGAGCTTCA CTTCTTTAAG CGGTTCTTTT ATACAGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002112	Ailuropoda melanoleuca	90.75	0.00e+00	1040.00
IUUC-Apl-003983	Anas platyrhynchos	92.70	0.00e+00	1059.00
IUUC-Aca-004300	Anolis carolinensis	92.53	0.00e+00	1056.00
IUUC-Ame-010621	Astyanax mexicanus	93.95	0.00e+00	1066.00
IUUC-Bta-013067	Bos taurus	90.21	0.00e+00	1035.00
IUUC-Cja-019687	Callithrix jacchus	90.57	0.00e+00	1033.00
IUUC-Cfa-020672	Canis familiaris	90.75	0.00e+00	1040.00
IUUC-Cpo-021819	Cavia porcellus	90.59	0.00e+00	1041.00
IUUC-Csa-023817	Chlorocebus sabaeus	90.39	0.00e+00	1035.00
IUUC-Cho-024387	Choloepus hoffmanni	75.37	6.00e-109	391.00
IUUC-Cin-025709	Ciona intestinalis	60.14	0.00e+00	709.00
IUUC-Csv-026336	Ciona savignyi	61.19	0.00e+00	719.00
IUUC-Dre-027717	Danio rerio	92.70	0.00e+00	1054.00
IUUC-Dno-029296	Dasypus novemcinctus	89.86	0.00e+00	1029.00
IUUC-Dor-030979	Dipodomys ordii	89.33	0.00e+00	865.00
IUUC-Dme-032171	Drosophila melanogaster	65.54	0.00e+00	741.00
IUUC-Eca-034046	Equus caballus	90.39	0.00e+00	1037.00
IUUC-Eeu-034859	Erinaceus europaeus	87.05	1.00e-139	493.00
IUUC-Fca-036262	Felis catus	90.93	0.00e+00	1045.00
IUUC-Fal-037562	Ficedula albicollis	92.53	0.00e+00	1055.00
IUUC-Gmo-038739	Gadus morhua	95.45	0.00e+00	1064.00
IUUC-Gga-040359	Gallus gallus	92.53	0.00e+00	1055.00
IUUC-Ggo-044692	Gorilla gorilla	89.86	0.00e+00	1025.00
IUUC-Hsa-045995	Homo sapiens	90.57	0.00e+00	1038.00
IUUC-Lch-049808	Latimeria chalumnae	92.73	0.00e+00	1056.00
IUUC-Loc-052685	Lepisosteus oculatus	93.62	0.00e+00	1061.00
IUUC-Laf-053372	Loxodonta africana	90.04	0.00e+00	1032.00
IUUC-Mcc-054693	Macaca mulatta	90.39	0.00e+00	1037.00
IUUC-Meu-056660	Macropus eugenii	90.57	0.00e+00	1025.00
IUUC-Mga-059371	Meleagris gallopavo	92.38	0.00e+00	1052.00
IUUC-Mmr-060787	Microcebus murinus	90.75	0.00e+00	1038.00
IUUC-Mdo-062518	Monodelphis domestica	92.70	0.00e+00	1057.00
IUUC-Mmu-063690	Mus musculus	90.75	0.00e+00	1041.00
IUUC-Mpu-066478	Mustela putorius furo	90.75	0.00e+00	1041.00
IUUC-Opr-070990	Ochotona princeps	90.93	0.00e+00	1038.00
IUUC-Ont-072285	Oreochromis niloticus	94.84	0.00e+00	1078.00
IUUC-Oan-072721	Ornithorhynchus anatinus	90.60	0.00e+00	1031.00
IUUC-Ocu-074273	Oryctolagus cuniculus	90.93	0.00e+00	1046.00
IUUC-Ola-087346	Oryzias latipes	92.21	0.00e+00	1042.00
IUUC-Oga-088742	Otolemur garnettii	90.57	0.00e+00	1035.00
IUUC-Oar-090093	Ovis aries	90.57	0.00e+00	1037.00
IUUC-Ptr-091034	Pan troglodytes	90.57	0.00e+00	1038.00
IUUC-Pan-092783	Papio anubis	90.57	0.00e+00	1036.00
IUUC-Psi-094027	Pelodiscus sinensis	92.18	0.00e+00	1049.00
IUUC-Pfo-097354	Poecilia formosa	96.72	0.00e+00	1075.00
IUUC-Pva-103147	Pteropus vampyrus	78.85	0.00e+00	655.00
IUUC-Rno-105458	Rattus norvegicus	90.75	0.00e+00	1040.00
IUUC-Sha-106959	Sarcophilus harrisii	76.42	0.00e+00	828.00
IUUC-Sar-113532	Sorex araneus	74.63	3.00e-103	372.00
IUUC-Ssc-116304	Sus scrofa	89.13	0.00e+00	736.00
IUUC-Tgu-116789	Taeniopygia guttata	92.38	0.00e+00	1053.00
IUUC-Tru-118129	Takifugu rubripes	95.20	0.00e+00	1080.00
IUUC-Tsy-119302	Tarsius syrichta	83.97	3.00e-65	246.00
IUUC-Tni-120374	Tetraodon nigroviridis	95.20	0.00e+00	1079.00
IUUC-Tbe-128137	Tupaia belangeri	76.58	0.00e+00	842.00
IUUC-Ttr-128273	Tursiops truncatus	90.04	0.00e+00	1028.00
IUUC-Xtr-132185	Xenopus tropicalis	88.97	0.00e+00	1019.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence