iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000018295.2	ENSLACT00000020965.2	ENSLACP00000020825.2
ENSLACG00000018295.2	ENSLACT00000020966.1	ENSLACP00000020826.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-108	363.1	761	1091

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNSvLQcLsn+p l+e++ +  ++e++n+ n  ++kge+++++  ++++lw ++ ++ spr+++ ++++++ +f g
   Q: 761  TGLRNLGNTCYMNSVLQCLSNTPHLAEYFIRnYYQEDINRANILGHKGEVAEEFGVIMKALWAGQYRYLSPRDFKITIGRINDQFAG 847
           7*****************************9778899************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedk...selsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+qqD+qE+l fl+d+l+e+l+k +n ++++ee++d+    ++s++a++k+k+ n+s+i+ lFqgq+ks+++cl+c ++s ++e f+
   Q: 848  YAQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDNlndLKASEQAWSKHKQLNESIIVALFQGQFKSTVQCLTCLKKSRTFEAFM 934
           *********************9966655555555553111566777***************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           +lslp+ + +++   +lqdcL+ f+kee+l+++n++yc +ck ++++ kk++++klP++L +hLkRfs++ +   ++k++++v+fpl
   Q: 935  YLSLPLASTSKC---TLQDCLRLFSKEEKLTDNNRFYCGHCKTQRDSLKKIEIWKLPPILLVHLKRFSYEGR--WKQKLQTSVDFPL 1016
           ***********9...****************************************************99765..556********** PP
   S: 258  e.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           e Ldls++++ p+++    k+Y+L++v +H+G+l++GHY+ay+kn  k++W +fdD++V+e++ ++v++   s aY+lfY 
   Q: 1017 EnLDLSQYVIGPKNN---LKRYNLYGVSNHYGGLDGGHYTAYCKNvIKQRWNKFDDHEVSEISTSSVKS---SAAYILFYS 1091
           ***********9988...69*************************55666*******************...********7 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MPAVSSVPKE LYISTSLKEL NRKAEVKPEK ISTRSYVQSA CKLFKTAEEN RLDRDEERAY 60
VLYMKYLSVY ELIKNRTDFK RQQDYYLSLL GPTSFKKAVE EAEKLSESLK LRYEEAEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCGCGACC CAGTCTATTT AAGTCTGCAC CCATTGTGCC TGTCCTAGAA CCGCTGACTT 60
TGCCCCGGAA GCCGCTGATC TCGCCTGGAA GCCGAGGGAG GAAGTAGAAC TTCGCAACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF08969--USP8_dimer

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102354385

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	79.85	0.00e+00	829.00
IUUC-Apl-003226	Anas platyrhynchos	85.51	0.00e+00	821.00
IUUC-Aca-004936	Anolis carolinensis	61.51	0.00e+00	1166.00
IUUC-Ago-007959	Ashbya gossypii	35.93	1.00e-54	207.00
IUUC-Acl-008102	Aspergillus clavatus	32.50	3.00e-54	207.00
IUUC-Afl-008604	Aspergillus flavus	31.39	2.00e-52	201.00
IUUC-Afu-009001	Aspergillus fumigatus	32.78	8.00e-54	205.00
IUUC-Ani-009291	Aspergillus nidulans	31.39	1.00e-52	201.00
IUUC-Ang-009844	Aspergillus niger	32.67	2.00e-53	203.00
IUUC-Aor-010098	Aspergillus oryzae	31.39	7.00e-52	199.00
IUUC-Ate-010585	Aspergillus terreus	32.12	6.00e-53	202.00
IUUC-Ame-010960	Astyanax mexicanus	75.00	6.00e-82	296.00
IUUC-Bta-013008	Bos taurus	83.30	0.00e+00	840.00
IUUC-Bol-015281	Brassica oleracea	39.51	4.00e-52	199.00
IUUC-Bra-017228	Brassica rapa	40.73	5.00e-54	205.00
IUUC-Cel-018482	Caenorhabditis elegans	32.83	4.00e-51	196.00
IUUC-Cja-019173	Callithrix jacchus	84.31	0.00e+00	828.00
IUUC-Cfa-021243	Canis familiaris	80.04	0.00e+00	832.00
IUUC-Cpo-021522	Cavia porcellus	82.52	0.00e+00	833.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.54	5.00e-86	310.00
IUUC-Csa-023616	Chlorocebus sabaeus	84.31	0.00e+00	824.00
IUUC-Cho-024381	Choloepus hoffmanni	75.85	0.00e+00	689.00
IUUC-Cin-025287	Ciona intestinalis	50.00	2.00e-101	363.00
IUUC-Csv-026253	Ciona savignyi	48.05	2.00e-89	323.00
IUUC-Cne-026821	Cryptococcus neoformans	40.73	9.00e-77	282.00
IUUC-Dre-028440	Danio rerio	66.23	0.00e+00	739.00
IUUC-Dno-029039	Dasypus novemcinctus	80.04	0.00e+00	832.00
IUUC-Dor-031043	Dipodomys ordii	86.21	2.00e-125	443.00
IUUC-Dse-031463	Dothistroma septosporum	27.67	3.00e-44	174.00
IUUC-Dme-032089	Drosophila melanogaster	44.09	6.00e-83	301.00
IUUC-Ete-033040	Echinops telfairi	81.82	0.00e+00	649.00
IUUC-Eca-033449	Equus caballus	80.57	0.00e+00	847.00
IUUC-Eeu-034693	Erinaceus europaeus	86.64	2.00e-119	423.00
IUUC-Fca-035794	Felis catus	86.11	0.00e+00	796.00
IUUC-Fal-037322	Ficedula albicollis	83.44	0.00e+00	800.00
IUUC-Gmo-038584	Gadus morhua	68.35	0.00e+00	675.00
IUUC-Gga-041188	Gallus gallus	85.28	0.00e+00	817.00
IUUC-Gac-041850	Gasterosteus aculeatus	76.42	0.00e+00	746.00
IUUC-Ggo-045565	Gorilla gorilla	84.51	0.00e+00	830.00
IUUC-Hsa-046438	Homo sapiens	84.51	0.00e+00	830.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	62.46	0.00e+00	1238.00
IUUC-Kpa-049321	Komagataella pastoris	32.77	8.00e-48	185.00
IUUC-Loc-052769	Lepisosteus oculatus	77.91	0.00e+00	798.00
IUUC-Lma-053021	Leptosphaeria maculans	32.07	5.00e-55	209.00
IUUC-Laf-053432	Loxodonta africana	84.46	0.00e+00	818.00
IUUC-Mcc-055823	Macaca mulatta	84.31	0.00e+00	828.00
IUUC-Meu-056099	Macropus eugenii	88.85	1.00e-153	537.00
IUUC-Mla-059089	Melampsora laricipopulina	41.74	2.00e-71	264.00
IUUC-Mga-059739	Meleagris gallopavo	85.28	0.00e+00	815.00
IUUC-Mvi-060559	Microbotryum violaceum	41.85	3.00e-79	290.00
IUUC-Mmr-061158	Microcebus murinus	80.99	0.00e+00	826.00
IUUC-Mdo-061801	Monodelphis domestica	84.48	0.00e+00	832.00
IUUC-Mmu-063665	Mus musculus	54.40	4.00e-124	439.00
IUUC-Mpu-066738	Mustela putorius furo	80.76	0.00e+00	828.00
IUUC-Mlu-067307	Myotis lucifugus	84.51	0.00e+00	842.00
IUUC-Nfi-068410	Neosartorya fischeri	32.58	7.00e-54	206.00
IUUC-Nle-069314	Nomascus leucogenys	84.71	0.00e+00	833.00
IUUC-Opr-070378	Ochotona princeps	83.14	5.00e-115	409.00
IUUC-Ont-071545	Oreochromis niloticus	74.52	0.00e+00	754.00
IUUC-Oan-073537	Ornithorhynchus anatinus	83.37	0.00e+00	820.00
IUUC-Ocu-074193	Oryctolagus cuniculus	83.14	0.00e+00	835.00
IUUC-Ola-086622	Oryzias latipes	78.25	0.00e+00	736.00
IUUC-Oga-088271	Otolemur garnettii	79.15	0.00e+00	841.00
IUUC-Oar-090431	Ovis aries	83.53	0.00e+00	837.00
IUUC-Ptr-091339	Pan troglodytes	63.59	0.00e+00	1294.00
IUUC-Pan-092266	Papio anubis	82.62	5.00e-161	559.00
IUUC-Psi-093187	Pelodiscus sinensis	54.58	3.00e-128	452.00
IUUC-Pma-094626	Petromyzon marinus	56.41	4.00e-138	484.00
IUUC-Pfo-096463	Poecilia formosa	74.12	0.00e+00	742.00
IUUC-Pab-097645	Pongo abelii	84.31	0.00e+00	828.00
IUUC-Pva-103222	Pteropus vampyrus	83.91	0.00e+00	655.00
IUUC-Pgr-103408	Puccinia graminis	38.94	4.00e-58	220.00
IUUC-Ptt-103699	Puccinia triticina	47.55	7.00e-67	249.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	31.52	3.00e-52	200.00
IUUC-Rno-105510	Rattus norvegicus	83.23	0.00e+00	823.00
IUUC-Sce-106166	Saccharomyces cerevisiae	35.38	2.00e-52	201.00
IUUC-Sha-106879	Sarcophilus harrisii	82.64	0.00e+00	830.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	34.46	6.00e-48	185.00
IUUC-Sar-113019	Sorex araneus	59.52	0.00e+00	1190.00
IUUC-Sre-115031	Sporisorium reilianum	38.14	5.00e-71	263.00
IUUC-Ssc-116334	Sus scrofa	82.43	0.00e+00	827.00
IUUC-Tgu-117062	Taeniopygia guttata	83.64	0.00e+00	803.00
IUUC-Tru-117908	Takifugu rubripes	77.10	0.00e+00	730.00
IUUC-Tsy-118867	Tarsius syrichta	72.21	0.00e+00	716.00
IUUC-Tni-120206	Tetraodon nigroviridis	76.86	0.00e+00	734.00
IUUC-Tme-127144	Tuber melanosporum	41.88	3.00e-81	296.00
IUUC-Tbe-127877	Tupaia belangeri	86.93	3.00e-76	280.00
IUUC-Ttr-128580	Tursiops truncatus	80.04	0.00e+00	831.00
IUUC-Uma-129340	Ustilago maydis	39.38	2.00e-72	267.00
IUUC-Vpa-130541	Vicugna pacos	77.92	0.00e+00	798.00
IUUC-Xtr-132161	Xenopus tropicalis	76.53	0.00e+00	791.00
IUUC-Xma-134271	Xiphophorus maculatus	74.56	0.00e+00	744.00
IUUC-Yli-134561	Yarrowia lipolytica	37.39	2.00e-60	227.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence