iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117275

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01028975

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007321.1	ENSTGUT00000007650.1	ENSTGUP00000007572.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-113	379.1	705	1070

Active Site

Position(s)	Description	Evidence
1038	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 705  QNAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 789
           67899*******************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 790  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 873
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+  Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 874  TNENKISYIHLMAHFRMHTQIKSQTAALIGGFRSIIKPEWIRMFSAPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 960
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++fs eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Y
   Q: 961  ILaNDFSPEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNY 1047
           **99*************************************************************9999****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k+il+ekL+yAi++++gFels
   Q: 1048 SKKSILREKLRYAISMNTGFELS 1070
           ********************985 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MFSASQSSRA QFLDKARQAR EERRELKERE RAAVQLQALV RRFLCRCHLQ REIRREVEDF 60
FGTNECGSSK RSALSVFRIA RKLLFVFNPK EDKERFEKLC RCILNSMDVE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAGTG CCAGCCAATC CTCCAGGGCT CAGTTCCTGG ACAAGGCCCG GCAGGCGCGG 60
GAGGAGCGGC GGGAGCTGAA GGAGAGGGAG AGAGCTGCAG TGCAGCTCCA GGCTCTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.61	2.00e-106	380.00
IUUC-Aml-002107	Ailuropoda melanoleuca	88.22	0.00e+00	1900.00
IUUC-Atr-003017	Amborella trichopoda	38.83	1.00e-110	394.00
IUUC-Apl-003328	Anas platyrhynchos	97.46	0.00e+00	2014.00
IUUC-Aly-005794	Arabidopsis lyrata	39.29	2.00e-109	390.00
IUUC-Ath-007269	Arabidopsis thaliana	39.46	3.00e-112	399.00
IUUC-Bta-013547	Bos taurus	87.85	0.00e+00	1902.00
IUUC-Bdi-014502	Brachypodium distachyon	39.25	2.00e-110	394.00
IUUC-Bol-015093	Brassica oleracea	39.82	2.00e-112	400.00
IUUC-Bra-016722	Brassica rapa	40.18	3.00e-114	406.00
IUUC-Cel-018447	Caenorhabditis elegans	38.65	0.00e+00	677.00
IUUC-Cja-019855	Callithrix jacchus	88.04	0.00e+00	1895.00
IUUC-Cfa-020066	Canis familiaris	87.72	0.00e+00	1875.00
IUUC-Cpo-021504	Cavia porcellus	87.29	0.00e+00	1887.00
IUUC-Csa-023579	Chlorocebus sabaeus	88.13	0.00e+00	1896.00
IUUC-Cho-024430	Choloepus hoffmanni	77.72	0.00e+00	1377.00
IUUC-Cin-025750	Ciona intestinalis	46.79	0.00e+00	933.00
IUUC-Csv-026016	Ciona savignyi	47.93	0.00e+00	993.00
IUUC-Dre-028271	Danio rerio	84.39	0.00e+00	1819.00
IUUC-Dno-029054	Dasypus novemcinctus	88.41	0.00e+00	1907.00
IUUC-Dor-030938	Dipodomys ordii	90.57	0.00e+00	1148.00
IUUC-Dme-031602	Drosophila melanogaster	48.39	0.00e+00	943.00
IUUC-Ete-033041	Echinops telfairi	71.96	0.00e+00	1264.00
IUUC-Eca-034411	Equus caballus	88.41	0.00e+00	1879.00
IUUC-Eeu-035201	Erinaceus europaeus	84.05	0.00e+00	799.00
IUUC-Fca-036594	Felis catus	87.29	0.00e+00	1861.00
IUUC-Fal-037317	Ficedula albicollis	94.62	0.00e+00	2059.00
IUUC-Gmo-039412	Gadus morhua	80.49	0.00e+00	1759.00
IUUC-Gga-040149	Gallus gallus	97.66	0.00e+00	2069.00
IUUC-Gac-042088	Gasterosteus aculeatus	82.95	0.00e+00	1820.00
IUUC-Gma-042728	Glycine max	40.85	4.00e-112	399.00
IUUC-Ggo-045279	Gorilla gorilla	87.76	0.00e+00	1887.00
IUUC-Hsa-045660	Homo sapiens	87.57	0.00e+00	1883.00
IUUC-Hvu-047102	Hordeum vulgare	39.72	6.00e-106	378.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	80.41	0.00e+00	883.00
IUUC-Lch-050664	Latimeria chalumnae	86.27	0.00e+00	1880.00
IUUC-Lpe-050755	Leersia perrieri	37.28	6.00e-99	355.00
IUUC-Loc-052791	Lepisosteus oculatus	85.75	0.00e+00	1838.00
IUUC-Laf-053902	Loxodonta africana	88.69	0.00e+00	1917.00
IUUC-Mcc-054730	Macaca mulatta	88.22	0.00e+00	1896.00
IUUC-Meu-056527	Macropus eugenii	80.22	0.00e+00	1699.00
IUUC-Mtr-057671	Medicago truncatula	39.96	2.00e-112	400.00
IUUC-Mga-059260	Meleagris gallopavo	97.85	0.00e+00	2074.00
IUUC-Mmr-060804	Microcebus murinus	86.36	0.00e+00	1824.00
IUUC-Mdo-062575	Monodelphis domestica	84.87	0.00e+00	1812.00
IUUC-Mmu-063636	Mus musculus	85.89	0.00e+00	1804.00
IUUC-Mac-064989	Musa acuminata	39.36	7.00e-108	385.00
IUUC-Mpu-066677	Mustela putorius furo	87.69	0.00e+00	1769.00
IUUC-Mlu-067952	Myotis lucifugus	88.04	0.00e+00	1857.00
IUUC-Nle-069153	Nomascus leucogenys	87.57	0.00e+00	1884.00
IUUC-Opr-070554	Ochotona princeps	89.07	0.00e+00	1766.00
IUUC-Ont-071372	Oreochromis niloticus	83.93	0.00e+00	1826.00
IUUC-Oan-073327	Ornithorhynchus anatinus	74.05	0.00e+00	768.00
IUUC-Ocu-074183	Oryctolagus cuniculus	86.45	0.00e+00	1857.00
IUUC-Oba-075213	Oryza barthii	38.82	4.00e-107	382.00
IUUC-Obr-076320	Oryza brachyantha	39.09	6.00e-110	391.00
IUUC-Ogl-077093	Oryza glaberrima	38.99	1.00e-109	391.00
IUUC-Oin-080058	Oryza indica	39.09	1.00e-109	391.00
IUUC-Olo-080742	Oryza longistaminata	38.82	2.00e-108	387.00
IUUC-Ome-081741	Oryza meridionalis	38.87	4.00e-102	366.00
IUUC-Opu-083529	Oryza punctata	38.99	1.00e-109	390.00
IUUC-Oru-085128	Oryza rufipogon	36.69	4.00e-96	345.00
IUUC-Osa-085557	Oryza sativa	39.09	4.00e-109	388.00
IUUC-Ola-087337	Oryzias latipes	83.55	0.00e+00	1770.00
IUUC-Oga-088342	Otolemur garnettii	87.77	0.00e+00	1840.00
IUUC-Oar-090234	Ovis aries	87.35	0.00e+00	1870.00
IUUC-Ptr-091661	Pan troglodytes	87.76	0.00e+00	1887.00
IUUC-Pan-092728	Papio anubis	87.86	0.00e+00	1889.00
IUUC-Psi-093251	Pelodiscus sinensis	94.34	0.00e+00	1869.00
IUUC-Pma-094195	Petromyzon marinus	70.31	0.00e+00	1469.00
IUUC-Ppa-095544	Physcomitrella patens	38.03	3.00e-111	396.00
IUUC-Pfo-097472	Poecilia formosa	84.02	0.00e+00	1837.00
IUUC-Pab-098570	Pongo abelii	87.76	0.00e+00	1887.00
IUUC-Pca-100110	Procavia capensis	77.29	0.00e+00	1581.00
IUUC-Ppe-101281	Prunus persica	39.18	1.00e-107	384.00
IUUC-Pva-102887	Pteropus vampyrus	83.29	0.00e+00	1753.00
IUUC-Rno-106028	Rattus norvegicus	82.63	0.00e+00	1720.00
IUUC-Sha-107331	Sarcophilus harrisii	85.73	0.00e+00	1833.00
IUUC-Smo-109488	Selaginella moellendorffii	37.32	5.00e-107	382.00
IUUC-Sit-109811	Setaria italica	39.25	2.00e-109	390.00
IUUC-Sar-113287	Sorex araneus	73.43	1.00e-174	607.00
IUUC-Sbi-114433	Sorghum bicolor	39.39	2.00e-110	393.00
IUUC-Ssc-116103	Sus scrofa	88.22	0.00e+00	1878.00
IUUC-Tru-118681	Takifugu rubripes	82.34	0.00e+00	1820.00
IUUC-Tsy-118985	Tarsius syrichta	78.52	0.00e+00	871.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.73	0.00e+00	777.00
IUUC-Tca-121770	Theobroma cacao	39.36	4.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.51	3.00e-106	379.00
IUUC-Tur-126086	Triticum urartu	39.78	6.00e-106	379.00
IUUC-Tbe-127461	Tupaia belangeri	83.64	0.00e+00	1721.00
IUUC-Ttr-129269	Tursiops truncatus	87.76	0.00e+00	1861.00
IUUC-Vpa-130523	Vicugna pacos	78.86	1.00e-118	420.00
IUUC-Vvi-131524	Vitis vinifera	39.04	1.00e-109	391.00
IUUC-Xtr-132146	Xenopus tropicalis	87.13	0.00e+00	1883.00
IUUC-Xma-133526	Xiphophorus maculatus	83.93	0.00e+00	1834.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence