iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.20e-06	28.5	685	734

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedl 55
           +f C +       Pvv+p+G+ty   ++ ++++ +   cP++++pl e ++
   Q: 685  DFDCVVCSRTLWKPVVTPCGHTYCLVCLDRCMDYNSP-CPLCMSPLVEFNV 734
           7889999999999******************888887.********88765 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPLSQGYCQQ EQQDQGHHMP PSSPIQCYLP HNDSQNSLHY LLAESFAKVG SLPEAFDVYE 60
LIASRQFDGH VPLDKLNTLA SALTTHIRQM GGIATPTPTP TPTPMSAVHV KSPRISERLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCATTCG CTGTTGAACA GCGGCCGTGG CAAGTTCAGA CAGCAGGGAG AGTTTGAAAA 60
AAAAAACCAG GCCGTAATAC AAATACAAAA AGCAAAATAA TAAAAATTAT ACAAAAAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

dme:Dmel_CG32369

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001989	Ailuropoda melanoleuca	36.73	6.00e-66	244.00
IUUC-Atr-002972	Amborella trichopoda	30.36	4.00e-27	115.00
IUUC-Apl-003355	Anas platyrhynchos	38.53	2.00e-68	252.00
IUUC-Aca-004822	Anolis carolinensis	37.83	4.00e-68	252.00
IUUC-Aly-005476	Arabidopsis lyrata	29.52	5.00e-27	114.00
IUUC-Ath-006654	Arabidopsis thaliana	29.96	2.00e-26	112.00
IUUC-Acl-008224	Aspergillus clavatus	28.49	1.00e-31	130.00
IUUC-Afu-008802	Aspergillus fumigatus	24.20	3.00e-30	125.00
IUUC-Ani-009473	Aspergillus nidulans	26.39	7.00e-31	128.00
IUUC-Ang-009643	Aspergillus niger	23.90	8.00e-26	111.00
IUUC-Ate-010489	Aspergillus terreus	26.15	3.00e-30	125.00
IUUC-Ame-010750	Astyanax mexicanus	38.55	3.00e-65	242.00
IUUC-Bta-012903	Bos taurus	36.95	2.00e-65	243.00
IUUC-Bdi-014333	Brachypodium distachyon	29.50	2.00e-25	109.00
IUUC-Bol-016442	Brassica oleracea	26.33	5.00e-29	121.00
IUUC-Bra-016716	Brassica rapa	25.45	1.00e-24	107.00
IUUC-Cja-019312	Callithrix jacchus	36.95	9.00e-66	244.00
IUUC-Cfa-020159	Canis familiaris	36.66	2.00e-65	243.00
IUUC-Cpo-022528	Cavia porcellus	36.36	5.00e-62	231.00
IUUC-Csa-023361	Chlorocebus sabaeus	37.24	3.00e-63	236.00
IUUC-Cho-024549	Choloepus hoffmanni	36.39	3.00e-52	198.00
IUUC-Cin-025668	Ciona intestinalis	32.29	2.00e-51	196.00
IUUC-Csv-026364	Ciona savignyi	34.15	6.00e-54	203.00
IUUC-Cgl-026514	Colletotrichum gloeosporioides	29.60	8.00e-34	137.00
IUUC-Cne-026875	Cryptococcus neoformans	34.04	2.00e-05	43.50
IUUC-Cme-027153	Cyanidioschyzon merolae	36.84	2.00e-13	69.30
IUUC-Dre-028400	Danio rerio	37.35	2.00e-64	239.00
IUUC-Dno-029284	Dasypus novemcinctus	36.36	3.00e-65	241.00
IUUC-Dor-031132	Dipodomys ordii	36.34	9.00e-64	237.00
IUUC-Dse-031331	Dothistroma septosporum	27.60	1.00e-31	130.00
IUUC-Ete-032455	Echinops telfairi	36.44	3.00e-62	231.00
IUUC-Eca-033248	Equus caballus	36.66	1.00e-63	236.00
IUUC-Eeu-034441	Erinaceus europaeus	36.95	4.00e-66	244.00
IUUC-Fca-035551	Felis catus	36.95	3.00e-66	245.00
IUUC-Fal-036669	Ficedula albicollis	39.69	7.00e-68	250.00
IUUC-Fso-038334	Fusarium solani	27.50	1.00e-30	126.00
IUUC-Gmo-039511	Gadus morhua	37.06	2.00e-60	225.00
IUUC-Gga-040888	Gallus gallus	37.76	6.00e-68	250.00
IUUC-Gac-041782	Gasterosteus aculeatus	37.43	5.00e-63	234.00
IUUC-Gma-042919	Glycine max	25.00	8.00e-21	94.00
IUUC-Ggo-044985	Gorilla gorilla	36.95	1.00e-65	243.00
IUUC-Hsa-046592	Homo sapiens	36.95	1.00e-65	243.00
IUUC-Hvu-047145	Hordeum vulgare	28.24	2.00e-12	65.50
IUUC-Itr-048573	Ictidomys tridecemlineatus	36.95	8.00e-66	244.00
IUUC-Kpa-049300	Komagataella pastoris	37.68	5.00e-08	50.80
IUUC-Lch-049788	Latimeria chalumnae	37.17	4.00e-67	248.00
IUUC-Loc-051922	Lepisosteus oculatus	38.25	4.00e-66	245.00
IUUC-Lma-053145	Leptosphaeria maculans	27.55	1.00e-31	130.00
IUUC-Laf-053434	Loxodonta africana	34.20	5.00e-62	231.00
IUUC-Mcc-055249	Macaca mulatta	31.01	4.00e-65	241.00
IUUC-Meu-055901	Macropus eugenii	38.50	2.00e-39	156.00
IUUC-Mor-056963	Magnaporthe oryzae	26.63	6.00e-28	118.00
IUUC-Mtr-058075	Medicago truncatula	25.51	2.00e-26	112.00
IUUC-Mla-058946	Melampsora laricipopulina	27.22	2.00e-30	125.00
IUUC-Mga-059760	Meleagris gallopavo	38.24	4.00e-68	251.00
IUUC-Mvi-060228	Microbotryum violaceum	28.12	4.00e-33	136.00
IUUC-Mmr-061283	Microcebus murinus	37.24	6.00e-66	244.00
IUUC-Mdo-062203	Monodelphis domestica	27.74	4.00e-73	268.00
IUUC-Mmu-064118	Mus musculus	38.42	8.00e-64	237.00
IUUC-Mac-065566	Musa acuminata	27.82	1.00e-24	107.00
IUUC-Mpu-066537	Mustela putorius furo	36.95	7.00e-63	234.00
IUUC-Mlu-067497	Myotis lucifugus	36.36	4.00e-65	241.00
IUUC-Nfi-068337	Neosartorya fischeri	26.39	4.00e-31	128.00
IUUC-Nle-068971	Nomascus leucogenys	36.95	9.00e-66	243.00
IUUC-Opr-070791	Ochotona princeps	36.95	6.00e-65	240.00
IUUC-Ont-072142	Oreochromis niloticus	37.54	6.00e-68	251.00
IUUC-Oan-073179	Ornithorhynchus anatinus	35.61	2.00e-62	232.00
IUUC-Ocu-074928	Oryctolagus cuniculus	36.95	3.00e-66	244.00
IUUC-Oba-075239	Oryza barthii	27.98	3.00e-25	108.00
IUUC-Obr-076158	Oryza brachyantha	29.49	6.00e-27	114.00
IUUC-Ogu-078154	Oryza glumaepatula	27.57	2.00e-25	109.00
IUUC-Oin-079067	Oryza indica	27.98	2.00e-25	110.00
IUUC-Olo-080663	Oryza longistaminata	27.98	2.00e-25	108.00
IUUC-Oni-082119	Oryza nivara	27.98	2.00e-25	108.00
IUUC-Opu-083266	Oryza punctata	27.32	8.00e-17	80.90
IUUC-Oru-085190	Oryza rufipogon	27.98	4.00e-25	108.00
IUUC-Ola-086534	Oryzias latipes	37.61	2.00e-67	249.00
IUUC-Oga-088719	Otolemur garnettii	37.24	4.00e-66	245.00
IUUC-Oar-089577	Ovis aries	36.95	5.00e-66	244.00
IUUC-Ptr-090711	Pan troglodytes	36.95	2.00e-65	243.00
IUUC-Pan-092379	Papio anubis	28.61	1.00e-68	253.00
IUUC-Psi-093423	Pelodiscus sinensis	38.74	1.00e-67	249.00
IUUC-Pma-094231	Petromyzon marinus	38.80	4.00e-58	217.00
IUUC-Pno-094889	Phaeosphaeria nodorum	34.01	7.00e-32	130.00
IUUC-Ppa-095945	Physcomitrella patens	40.82	2.00e-08	52.80
IUUC-Pfo-096363	Poecilia formosa	37.35	1.00e-63	236.00
IUUC-Pab-098343	Pongo abelii	28.97	2.00e-69	256.00
IUUC-Pop-100044	Populus trichocarpa	26.07	1.00e-28	120.00
IUUC-Pca-100905	Procavia capensis	36.36	1.00e-40	160.00
IUUC-Ppe-101621	Prunus persica	30.77	9.00e-21	94.00
IUUC-Pva-102242	Pteropus vampyrus	41.50	2.00e-46	179.00
IUUC-Pgr-103289	Puccinia graminis	24.44	6.00e-23	101.00
IUUC-Ptt-103898	Puccinia triticina	24.87	4.00e-23	102.00
IUUC-Pte-104214	Pyrenophora teres	28.10	2.00e-29	123.00
IUUC-Pyt-104565	Pyrenophora triticirepentis	28.10	1.00e-29	123.00
IUUC-Rno-105905	Rattus norvegicus	37.83	9.00e-64	236.00
IUUC-Sce-106454	Saccharomyces cerevisiae	43.59	2.00e-06	46.60
IUUC-Sha-107565	Sarcophilus harrisii	34.23	4.00e-58	218.00
IUUC-Sja-107742	Schizosaccharomyces japonicus	28.57	6.00e-21	94.40
IUUC-Spo-108344	Schizosaccharomyces pombe	23.80	2.00e-13	69.30
IUUC-Ssl-108430	Sclerotinia sclerotiorum	37.10	1.00e-07	50.40
IUUC-Sit-110495	Setaria italica	29.76	9.00e-28	117.00
IUUC-Sly-111396	Solanum lycopersicum	25.22	1.00e-23	103.00
IUUC-Sar-113220	Sorex araneus	35.88	2.00e-62	231.00
IUUC-Sbi-114779	Sorghum bicolor	27.71	1.00e-14	73.60
IUUC-Sre-114977	Sporisorium reilianum	30.51	2.00e-33	137.00
IUUC-Ssc-115733	Sus scrofa	36.36	2.00e-65	243.00
IUUC-Tgu-117431	Taeniopygia guttata	37.76	4.00e-68	251.00
IUUC-Tru-118016	Takifugu rubripes	37.91	3.00e-64	239.00
IUUC-Tsy-119043	Tarsius syrichta	36.66	3.00e-65	242.00
IUUC-Tni-119913	Tetraodon nigroviridis	37.99	8.00e-65	240.00
IUUC-Tca-121632	Theobroma cacao	27.53	1.00e-27	117.00
IUUC-Tae-122863	Triticum aestivum	29.03	5.00e-26	111.00
IUUC-Tur-126297	Triticum urartu	27.71	4.00e-19	89.00
IUUC-Tme-127112	Tuber melanosporum	29.76	2.00e-32	132.00
IUUC-Tbe-127284	Tupaia belangeri	35.48	6.00e-61	227.00
IUUC-Ttr-128875	Tursiops truncatus	36.67	2.00e-62	232.00
IUUC-Uma-129541	Ustilago maydis	28.10	2.00e-32	134.00
IUUC-Vda-129721	Verticillium dahliae	27.56	6.00e-16	77.80
IUUC-Vpa-130408	Vicugna pacos	36.63	3.00e-60	225.00
IUUC-Vvi-130910	Vitis vinifera	26.47	2.00e-23	102.00
IUUC-Xtr-132065	Xenopus tropicalis	37.36	7.00e-68	251.00
IUUC-Xma-134324	Xiphophorus maculatus	37.80	9.00e-65	241.00
IUUC-Zma-135914	Zea mays	24.23	3.00e-19	88.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence