iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116949

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01002494

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000011165.1	ENSTGUT00000011655.1	ENSTGUP00000011530.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	2.30e-38	130.0	181	257
E3 activity/RING/RING	1.90e-07	31.3	1057	1161
E3 activity/N-recognin/UBR-box	3.30e-29	101.0	51	121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al +e+ ea++++t+idkeGRravkaG ya c+eak+ei+++se+++q pL+Vev
   Q: 181  YYCVLFNDEHHSYDHVIYSLQRALGCELGEAQLHTTAIDKEGRRAVKAGHYASCQEAKEEIKRHSENVSQRPLHVEV 257
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd..............................gplvlpCgHvfhadClqkw............. 29
           C++C+e+                ++                              g+++++CgHv+ha C+qk+             
   Q: 1057 CILCQEEQevklesaamvlsacvQKstaltqnrsrilelsgdaldplfmhpdlpcGTHTGSCGHVMHAACWQKYfeamqlnfrqrlh 1143
           78885555333333333333333003333333333333333333333333333337999***************************9 PP
   S: 30   .pglknssskefrCPlCr 46
             +  +++++e +CPlC+
   Q: 1144 vEQIFDLENGEYLCPLCK 1161
           99999999*********7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk get+y+Cr+C+vd+t+vlC +Cf++++Hk+H+yk++ s+gggfCdCGdteAw+ g+ C k++
   Q: 51   QLCGKVFKGGETTYSCRDCAVDPTCVLCIDCFQNSIHKNHRYKMHSSTGGGFCDCGDTEAWKAGPLCTKHE 121
           68******************************************************************996 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

VPNIYSAEMD PLVEKQEEMV QAAILYPLEC YLFGEDPDIF LEKLQQSGTS QLCGKVFKGG 60
ETTYSCRDCA VDPTCVLCID CFQNSIHKNH RYKMHSSTGG GFCDCGDTEA WKAGPLCTKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCCAAATA TTTACTCAGC TGAAATGGAC CCCTTGGTGG AGAAACAAGA AGAAATGGTC 60
CAGGCAGCAA TATTATACCC CCTAGAATGT TATTTGTTTG GGGAGGACCC AGATATATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	72.49	0.00e+00	2503.00
IUUC-Apl-004160	Anas platyrhynchos	86.54	0.00e+00	2939.00
IUUC-Aca-004982	Anolis carolinensis	73.58	0.00e+00	2520.00
IUUC-Ate-010550	Aspergillus terreus	23.58	3.00e-45	177.00
IUUC-Ame-011231	Astyanax mexicanus	56.72	0.00e+00	1854.00
IUUC-Bgr-011999	Blumeria graminis	23.48	3.00e-50	194.00
IUUC-Bta-012347	Bos taurus	72.74	0.00e+00	2489.00
IUUC-Bci-013834	Botrytis cinerea	23.05	1.00e-50	195.00
IUUC-Cja-018911	Callithrix jacchus	72.36	0.00e+00	2494.00
IUUC-Cfa-020991	Canis familiaris	73.24	0.00e+00	2532.00
IUUC-Cpo-021448	Cavia porcellus	72.08	0.00e+00	2479.00
IUUC-Cre-022821	Chlamydomonas reinhardtii	23.48	9.00e-01	28.90
IUUC-Csa-024255	Chlorocebus sabaeus	74.16	0.00e+00	2085.00
IUUC-Cho-024550	Choloepus hoffmanni	56.91	0.00e+00	1803.00
IUUC-Dno-029427	Dasypus novemcinctus	72.03	0.00e+00	2450.00
IUUC-Dor-031073	Dipodomys ordii	72.08	0.00e+00	1174.00
IUUC-Dme-031910	Drosophila melanogaster	31.92	0.00e+00	738.00
IUUC-Ete-032318	Echinops telfairi	63.15	0.00e+00	997.00
IUUC-Eca-033348	Equus caballus	72.98	0.00e+00	2391.00
IUUC-Eeu-034664	Erinaceus europaeus	66.11	0.00e+00	2243.00
IUUC-Fal-037333	Ficedula albicollis	88.30	0.00e+00	2988.00
IUUC-Gmo-039363	Gadus morhua	53.92	0.00e+00	1591.00
IUUC-Gga-040486	Gallus gallus	86.40	0.00e+00	2855.00
IUUC-Gac-041985	Gasterosteus aculeatus	55.61	0.00e+00	1671.00
IUUC-Ggo-044704	Gorilla gorilla	67.17	0.00e+00	1928.00
IUUC-Hsa-046753	Homo sapiens	73.31	0.00e+00	2531.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	73.01	0.00e+00	2516.00
IUUC-Lch-049904	Latimeria chalumnae	62.12	0.00e+00	2087.00
IUUC-Loc-052624	Lepisosteus oculatus	60.31	0.00e+00	1952.00
IUUC-Laf-053857	Loxodonta africana	72.86	0.00e+00	2519.00
IUUC-Mcc-054873	Macaca mulatta	73.14	0.00e+00	2501.00
IUUC-Meu-056858	Macropus eugenii	62.30	0.00e+00	971.00
IUUC-Mga-059917	Meleagris gallopavo	86.74	0.00e+00	2965.00
IUUC-Mmr-061128	Microcebus murinus	69.52	0.00e+00	2324.00
IUUC-Mdo-062306	Monodelphis domestica	73.14	0.00e+00	2498.00
IUUC-Mmu-063389	Mus musculus	72.39	0.00e+00	2498.00
IUUC-Mpu-065983	Mustela putorius furo	73.64	0.00e+00	2540.00
IUUC-Mlu-068013	Myotis lucifugus	71.45	0.00e+00	2435.00
IUUC-Nle-070031	Nomascus leucogenys	73.19	0.00e+00	2529.00
IUUC-Opr-070551	Ochotona princeps	56.98	0.00e+00	1032.00
IUUC-Ont-072035	Oreochromis niloticus	56.54	0.00e+00	1885.00
IUUC-Ocu-074930	Oryctolagus cuniculus	72.53	0.00e+00	2478.00
IUUC-Oba-075295	Oryza barthii	42.71	8.00e-15	76.60
IUUC-Ogu-078497	Oryza glumaepatula	42.71	8.00e-15	77.00
IUUC-Oin-079343	Oryza indica	42.71	9.00e-15	76.60
IUUC-Oni-083099	Oryza nivara	42.71	9.00e-15	76.60
IUUC-Oru-084471	Oryza rufipogon	42.71	9.00e-15	76.60
IUUC-Osa-086106	Oryza sativa	40.19	1.00e-12	68.20
IUUC-Ola-086683	Oryzias latipes	56.34	0.00e+00	1841.00
IUUC-Oga-088017	Otolemur garnettii	70.17	0.00e+00	2387.00
IUUC-Oar-089557	Ovis aries	72.35	0.00e+00	2482.00
IUUC-Ptr-091366	Pan troglodytes	72.62	0.00e+00	2490.00
IUUC-Pan-092184	Papio anubis	73.19	0.00e+00	2501.00
IUUC-Psi-093720	Pelodiscus sinensis	79.18	0.00e+00	2635.00
IUUC-Pma-094152	Petromyzon marinus	39.30	1.00e-144	506.00
IUUC-Pfo-097124	Poecilia formosa	56.66	0.00e+00	1866.00
IUUC-Pab-098586	Pongo abelii	73.25	0.00e+00	2522.00
IUUC-Pop-099184	Populus trichocarpa	40.20	2.00e-12	66.20
IUUC-Pca-100673	Procavia capensis	71.26	0.00e+00	1398.00
IUUC-Pva-102724	Pteropus vampyrus	77.07	0.00e+00	1823.00
IUUC-Pte-104174	Pyrenophora teres	24.51	5.00e-48	187.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	24.36	1.00e-47	185.00
IUUC-Rno-105474	Rattus norvegicus	68.07	0.00e+00	1749.00
IUUC-Sha-106993	Sarcophilus harrisii	73.53	0.00e+00	2541.00
IUUC-Sar-113447	Sorex araneus	73.11	0.00e+00	1694.00
IUUC-Sre-115045	Sporisorium reilianum	25.55	2.00e-45	178.00
IUUC-Ssc-115768	Sus scrofa	69.73	0.00e+00	2259.00
IUUC-Tru-117782	Takifugu rubripes	56.21	0.00e+00	1876.00
IUUC-Tsy-119177	Tarsius syrichta	62.91	0.00e+00	1632.00
IUUC-Tni-120884	Tetraodon nigroviridis	51.84	0.00e+00	1664.00
IUUC-Tvi-122272	Trichoderma virens	23.33	1.00e-52	202.00
IUUC-Tbe-128088	Tupaia belangeri	60.56	0.00e+00	874.00
IUUC-Ttr-129062	Tursiops truncatus	68.00	0.00e+00	2295.00
IUUC-Xtr-132244	Xenopus tropicalis	60.22	0.00e+00	2041.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence