iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.00	2.00e-144	509.00	IUUC-Hsa-045936
E3 activity/RING/RING	100.00	6.00e-159	556.00	IUUC-Mmu-063373

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSMPLHQISA IPSQDAISAR VYRSKTKDKE QNEKTLGHSM SHPSNISKAG SSPPSTTAPV 60
SAFSRTSVTP SNQDICRICH CEGDDESPLI TPCHCTGSLH FVHQACLQQW IKSSDTRCCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCGCTGGG TGGTGTAGGC TGCGTACTGA CCCAGCCGCC CTGCTGCGTC CGGCCTGTGT 60
CATGCAGGAA GCGGGCCGCG CGTGGAGCTG CGCGCCCACC TGAGCTGCTT GCGCCGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033275--MARCH-like
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002495--P:antigen processing and presentation of peptide antigen via MHC class II
GO:0045347--P:negative regulation of MHC class II biosynthetic process

KEGG

rno:312656

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013415	Bos taurus	87.59	1.00e-144	505.00
IUUC-Cel-018329	Caenorhabditis elegans	40.26	2.00e-11	63.50
IUUC-Cfa-020901	Canis familiaris	86.21	9.00e-142	495.00
IUUC-Cpo-021679	Cavia porcellus	90.27	4.00e-139	486.00
IUUC-Csa-023704	Chlorocebus sabaeus	85.22	3.00e-140	490.00
IUUC-Dre-027670	Danio rerio	78.97	1.00e-125	442.00
IUUC-Dno-028902	Dasypus novemcinctus	84.14	3.00e-140	490.00
IUUC-Dme-031717	Drosophila melanogaster	56.63	2.00e-60	226.00
IUUC-Eca-033918	Equus caballus	87.61	1.00e-124	438.00
IUUC-Gmo-039585	Gadus morhua	78.28	7.00e-125	439.00
IUUC-Gga-040516	Gallus gallus	86.81	1.00e-144	505.00
IUUC-Gac-041554	Gasterosteus aculeatus	77.93	7.00e-125	439.00
IUUC-Hsa-045936	Homo sapiens	86.60	4.00e-142	497.00
IUUC-Lch-049853	Latimeria chalumnae	80.69	6.00e-133	466.00
IUUC-Loc-052142	Lepisosteus oculatus	76.27	1.00e-123	435.00
IUUC-Laf-054075	Loxodonta africana	89.33	3.00e-120	424.00
IUUC-Mcc-054834	Macaca mulatta	85.57	9.00e-141	492.00
IUUC-Mmr-061603	Microcebus murinus	88.97	9.00e-151	525.00
IUUC-Mdo-062578	Monodelphis domestica	85.57	7.00e-143	499.00
IUUC-Mmu-063373	Mus musculus	100.00	3.00e-160	556.00
IUUC-Nle-069774	Nomascus leucogenys	85.91	2.00e-140	491.00
IUUC-Ocu-074342	Oryctolagus cuniculus	78.20	3.00e-121	427.00
IUUC-Ola-086344	Oryzias latipes	77.91	1.00e-113	402.00
IUUC-Oga-088670	Otolemur garnettii	88.76	7.00e-132	462.00
IUUC-Ptr-090574	Pan troglodytes	87.29	4.00e-143	500.00
IUUC-Pan-092925	Papio anubis	84.88	1.00e-139	489.00
IUUC-Psi-093085	Pelodiscus sinensis	85.86	1.00e-135	475.00
IUUC-Pma-094229	Petromyzon marinus	63.90	4.00e-73	267.00
IUUC-Pfo-097524	Poecilia formosa	78.57	1.00e-117	415.00
IUUC-Pab-098165	Pongo abelii	86.25	1.00e-141	495.00
IUUC-Sha-107014	Sarcophilus harrisii	85.78	2.00e-117	415.00
IUUC-Tru-117951	Takifugu rubripes	76.14	6.00e-106	376.00
IUUC-Tni-120496	Tetraodon nigroviridis	76.95	2.00e-109	388.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence