iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017713.4	ENSCAFT00000046614.2	ENSCAFP00000037523.1
ENSCAFG00000017713.4	ENSCAFT00000028094.3	ENSCAFP00000026134.3

Status

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.70e-54	185.3	183	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelki.kegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalk 89
           C++C+l+++++ +t  leC h+fC++C+++yl++ki +eg+ ++iscpa+ c   ++++++++l+++++++ +y++l ++++ve+++ lk
   Q: 183  CQICYLNYPNSYFTG-LECGHKFCMQCWSEYLTTKImEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLK 271
           **********99985.5**************87775277899************************************************ PP
   S: 90   wcpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnh 179
           wcpapdC++vv ++   +++ v+c kcg++fC++C e+wH++++Ck+lk++ +k++   +++e++++++an+k+CpkC+v+iek++gCnh
   Q: 272  WCPAPDCHHVVKVQYP-DAKPVRC-KCGRQFCFNCGENWHDPVKCKWLKKWIKKCD---DDSETSNWIAANTKECPKCHVTIEKDGGCNH 356
           ***************7.9999999.9******************************...99***************************** PP
   S: 180  mtC..akCkaefCwlC 193
           m C  ++CkaefCw+C
   Q: 357  MVCrnQNCKAEFCWVC 372
           ***9999********* PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDSDEGYNYE FDEDEECSEE DSGAEEEEDE DDDEPDDDNL DLGEVELVEP GLGVGGERDG 60
LLCGETGGGG GSALGPGGGG GGGGGGGGPG HEQEEDYRYE VLTAEQILQH MECIREVNEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNCCGCC GCGCCCGGGG AGGAGCCGCG GCCCGCGGGG CCGGAGCCAG GCCTGCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0097413--C:Lewy body
GO:0016604--C:nuclear body
GO:0019005--C:SCF ubiquitin ligase complex
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000970	Aegilops tauschii	30.43	9.00e-55	207.00
IUUC-Aml-001385	Ailuropoda melanoleuca	99.78	0.00e+00	920.00
IUUC-Atr-002480	Amborella trichopoda	31.54	9.00e-64	238.00
IUUC-Apl-004184	Anas platyrhynchos	98.42	0.00e+00	876.00
IUUC-Aca-004976	Anolis carolinensis	99.54	0.00e+00	877.00
IUUC-Aly-005807	Arabidopsis lyrata	32.37	2.00e-63	236.00
IUUC-Ath-007166	Arabidopsis thaliana	32.81	1.00e-63	237.00
IUUC-Ago-007926	Ashbya gossypii	29.37	1.00e-53	204.00
IUUC-Acl-008252	Aspergillus clavatus	42.49	7.00e-104	370.00
IUUC-Afl-008468	Aspergillus flavus	43.79	2.00e-105	376.00
IUUC-Afu-009062	Aspergillus fumigatus	44.69	3.00e-105	375.00
IUUC-Ani-009219	Aspergillus nidulans	42.73	5.00e-106	378.00
IUUC-Ang-009538	Aspergillus niger	43.29	4.00e-98	352.00
IUUC-Aor-010009	Aspergillus oryzae	43.79	7.00e-105	374.00
IUUC-Ate-010497	Aspergillus terreus	44.25	6.00e-98	351.00
IUUC-Ame-011264	Astyanax mexicanus	89.75	0.00e+00	955.00
IUUC-Bgr-012016	Blumeria graminis	41.40	1.00e-101	363.00
IUUC-Bta-013518	Bos taurus	99.78	0.00e+00	932.00
IUUC-Bci-013819	Botrytis cinerea	42.67	3.00e-106	378.00
IUUC-Bdi-014685	Brachypodium distachyon	32.59	3.00e-66	246.00
IUUC-Bol-016087	Brassica oleracea	31.94	4.00e-59	222.00
IUUC-Bra-017944	Brassica rapa	32.87	5.00e-54	205.00
IUUC-Cel-018521	Caenorhabditis elegans	55.04	5.00e-137	481.00
IUUC-Cja-019869	Callithrix jacchus	92.31	0.00e+00	838.00
IUUC-Cpo-021627	Cavia porcellus	99.78	0.00e+00	932.00
IUUC-Csa-023034	Chlorocebus sabaeus	100.00	0.00e+00	873.00
IUUC-Cho-024444	Choloepus hoffmanni	96.99	0.00e+00	899.00
IUUC-Cin-025135	Ciona intestinalis	68.90	0.00e+00	679.00
IUUC-Csv-026243	Ciona savignyi	68.39	0.00e+00	659.00
IUUC-Cgl-026434	Colletotrichum gloeosporioides	42.61	1.00e-106	380.00
IUUC-Cne-026861	Cryptococcus neoformans	41.98	5.00e-101	361.00
IUUC-Dre-027785	Danio rerio	89.94	0.00e+00	956.00
IUUC-Dno-029205	Dasypus novemcinctus	99.78	0.00e+00	932.00
IUUC-Dor-030769	Dipodomys ordii	82.18	0.00e+00	723.00
IUUC-Dse-031171	Dothistroma septosporum	43.53	5.00e-105	374.00
IUUC-Dme-031903	Drosophila melanogaster	70.35	0.00e+00	694.00
IUUC-Ete-032929	Echinops telfairi	83.96	9.00e-134	469.00
IUUC-Eca-033431	Equus caballus	99.55	0.00e+00	891.00
IUUC-Eeu-034838	Erinaceus europaeus	86.34	0.00e+00	753.00
IUUC-Fca-035882	Felis catus	95.88	0.00e+00	788.00
IUUC-Fal-037068	Ficedula albicollis	99.32	0.00e+00	890.00
IUUC-Fox-037790	Fusarium oxysporum	49.82	1.00e-77	282.00
IUUC-Fso-038125	Fusarium solani	42.83	7.00e-105	374.00
IUUC-Gmo-038703	Gadus morhua	90.15	0.00e+00	951.00
IUUC-Ggr-039722	Gaeumannomyces graminis	41.76	2.00e-104	372.00
IUUC-Gga-040319	Gallus gallus	100.00	0.00e+00	697.00
IUUC-Gac-041708	Gasterosteus aculeatus	96.51	0.00e+00	937.00
IUUC-Gma-043188	Glycine max	32.35	6.00e-59	221.00
IUUC-Ggo-045178	Gorilla gorilla	99.78	0.00e+00	932.00
IUUC-Hsa-045718	Homo sapiens	99.78	0.00e+00	932.00
IUUC-Hvu-047322	Hordeum vulgare	31.87	3.00e-57	216.00
IUUC-Itr-048934	Ictidomys tridecemlineatus	100.00	7.00e-178	615.00
IUUC-Kpa-049350	Komagataella pastoris	32.88	2.00e-63	236.00
IUUC-Lpe-051110	Leersia perrieri	33.18	5.00e-67	248.00
IUUC-Loc-052442	Lepisosteus oculatus	91.30	0.00e+00	966.00
IUUC-Lma-053253	Leptosphaeria maculans	44.03	3.00e-111	395.00
IUUC-Laf-054351	Loxodonta africana	100.00	0.00e+00	873.00
IUUC-Mcc-054670	Macaca mulatta	96.34	0.00e+00	921.00
IUUC-Meu-056335	Macropus eugenii	92.11	2.00e-142	498.00
IUUC-Mor-057179	Magnaporthe oryzae	43.08	6.00e-105	374.00
IUUC-Mpo-057553	Magnaporthe poae	41.76	2.00e-103	369.00
IUUC-Mtr-058263	Medicago truncatula	32.62	1.00e-57	217.00
IUUC-Mla-058889	Melampsora laricipopulina	37.09	9.00e-78	284.00
IUUC-Mga-059385	Meleagris gallopavo	98.65	0.00e+00	880.00
IUUC-Mvi-060517	Microbotryum violaceum	40.74	4.00e-104	371.00
IUUC-Mmr-061439	Microcebus murinus	93.16	0.00e+00	848.00
IUUC-Mdo-062890	Monodelphis domestica	99.57	0.00e+00	931.00
IUUC-Mmu-063433	Mus musculus	99.78	0.00e+00	932.00
IUUC-Mac-065341	Musa acuminata	33.79	3.00e-63	236.00
IUUC-Mpu-066288	Mustela putorius furo	99.78	0.00e+00	932.00
IUUC-Mlu-067187	Myotis lucifugus	99.57	0.00e+00	926.00
IUUC-Nfi-068339	Neosartorya fischeri	44.47	8.00e-105	374.00
IUUC-Ncr-068947	Neurospora crassa	43.53	1.00e-102	366.00
IUUC-Nle-069263	Nomascus leucogenys	99.78	0.00e+00	932.00
IUUC-Opr-071000	Ochotona princeps	100.00	1.00e-97	350.00
IUUC-Ont-072309	Oreochromis niloticus	96.31	0.00e+00	934.00
IUUC-Oan-073731	Ornithorhynchus anatinus	100.00	0.00e+00	831.00
IUUC-Ocu-074000	Oryctolagus cuniculus	98.19	0.00e+00	875.00
IUUC-Oba-075628	Oryza barthii	31.84	9.00e-61	228.00
IUUC-Obr-076492	Oryza brachyantha	32.74	2.00e-67	249.00
IUUC-Ogl-077447	Oryza glaberrima	33.18	6.00e-68	251.00
IUUC-Ogu-078881	Oryza glumaepatula	32.97	6.00e-68	251.00
IUUC-Oin-079573	Oryza indica	33.18	7.00e-67	248.00
IUUC-Olo-080774	Oryza longistaminata	33.19	2.00e-68	253.00
IUUC-Ome-081470	Oryza meridionalis	31.90	5.00e-58	218.00
IUUC-Oni-082267	Oryza nivara	31.83	2.00e-60	226.00
IUUC-Opu-084135	Oryza punctata	33.18	6.00e-68	251.00
IUUC-Oru-084849	Oryza rufipogon	32.97	1.00e-67	251.00
IUUC-Osa-085435	Oryza sativa	33.18	1.00e-67	250.00
IUUC-Ola-086792	Oryzias latipes	96.31	0.00e+00	933.00
IUUC-Olu-087826	Ostreococcus lucimarinus	32.90	3.00e-50	192.00
IUUC-Oga-088706	Otolemur garnettii	99.78	0.00e+00	932.00
IUUC-Oar-089354	Ovis aries	99.57	0.00e+00	932.00
IUUC-Ptr-091287	Pan troglodytes	99.78	0.00e+00	932.00
IUUC-Pan-091701	Papio anubis	100.00	0.00e+00	873.00
IUUC-Psi-093814	Pelodiscus sinensis	100.00	0.00e+00	873.00
IUUC-Pno-095124	Phaeosphaeria nodorum	35.71	7.00e-79	287.00
IUUC-Ppa-095545	Physcomitrella patens	32.44	2.00e-60	226.00
IUUC-Pfo-096449	Poecilia formosa	96.31	0.00e+00	933.00
IUUC-Pab-098132	Pongo abelii	99.78	0.00e+00	932.00
IUUC-Pop-099139	Populus trichocarpa	32.48	4.00e-63	235.00
IUUC-Pca-100303	Procavia capensis	99.70	0.00e+00	652.00
IUUC-Ppe-101740	Prunus persica	31.79	2.00e-58	219.00
IUUC-Pva-102457	Pteropus vampyrus	99.78	0.00e+00	932.00
IUUC-Pgr-103443	Puccinia graminis	42.32	3.00e-102	365.00
IUUC-Ptt-103795	Puccinia triticina	39.92	6.00e-92	331.00
IUUC-Pte-104022	Pyrenophora teres	40.99	1.00e-101	363.00
IUUC-Pyt-104643	Pyrenophora triticirepentis	42.58	5.00e-109	388.00
IUUC-Rno-106083	Rattus norvegicus	99.78	0.00e+00	932.00
IUUC-Sce-106154	Saccharomyces cerevisiae	30.63	7.00e-63	234.00
IUUC-Sha-106765	Sarcophilus harrisii	97.75	0.00e+00	881.00
IUUC-Sja-107977	Schizosaccharomyces japonicus	45.98	6.00e-98	351.00
IUUC-Spo-108222	Schizosaccharomyces pombe	44.73	4.00e-110	391.00
IUUC-Smo-108845	Selaginella moellendorffii	32.71	7.00e-58	218.00
IUUC-Sit-110348	Setaria italica	32.14	6.00e-64	238.00
IUUC-Sly-111454	Solanum lycopersicum	33.49	9.00e-61	228.00
IUUC-Stu-112599	Solanum tuberosum	32.95	1.00e-57	217.00
IUUC-Sar-113023	Sorex araneus	99.77	0.00e+00	867.00
IUUC-Sbi-114262	Sorghum bicolor	32.81	2.00e-65	243.00
IUUC-Sre-115120	Sporisorium reilianum	43.04	4.00e-111	395.00
IUUC-Ssc-115667	Sus scrofa	89.47	0.00e+00	628.00
IUUC-Tgu-117273	Taeniopygia guttata	99.54	0.00e+00	872.00
IUUC-Tru-118338	Takifugu rubripes	86.58	0.00e+00	931.00
IUUC-Tsy-119096	Tarsius syrichta	91.67	0.00e+00	778.00
IUUC-Tni-120238	Tetraodon nigroviridis	86.51	0.00e+00	928.00
IUUC-Tca-121037	Theobroma cacao	33.33	2.00e-65	243.00
IUUC-Tre-121902	Trichoderma reesei	42.70	4.00e-103	368.00
IUUC-Tvi-122474	Trichoderma virens	41.96	3.00e-103	369.00
IUUC-Tae-124132	Triticum aestivum	33.11	1.00e-66	247.00
IUUC-Tur-126320	Triticum urartu	30.75	3.00e-55	209.00
IUUC-Tme-127089	Tuber melanosporum	42.92	3.00e-104	372.00
IUUC-Tbe-127409	Tupaia belangeri	93.09	1.00e-121	429.00
IUUC-Ttr-128909	Tursiops truncatus	90.63	0.00e+00	808.00
IUUC-Uma-129487	Ustilago maydis	42.13	2.00e-110	392.00
IUUC-Vda-129939	Verticillium dahliae	42.40	4.00e-105	375.00
IUUC-Vpa-130259	Vicugna pacos	96.56	0.00e+00	889.00
IUUC-Vvi-131463	Vitis vinifera	32.52	1.00e-57	217.00
IUUC-Xtr-132219	Xenopus tropicalis	98.91	0.00e+00	916.00
IUUC-Xma-133423	Xiphophorus maculatus	96.31	0.00e+00	933.00
IUUC-Yli-134622	Yarrowia lipolytica	35.65	2.00e-72	266.00
IUUC-Zma-135131	Zea mays	33.11	7.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence