iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000006493.1	ENSOART00000007059.1	ENSOARP00000006952.1
ENSOARG00000006493.1	ENSOART00000007061.1	ENSOARP00000006954.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-28	96.4	530	560
UBD/Beta-Prp	8.80e-46	156.6	309	594

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           ++ f +d  + ++Gs+Dg +++WD++tg+l+ 
   Q: 530  AV-FsPDrSYALAGSWDGALYIWDVDTGKLES 560
           33.599999*******************9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+ l+ +   +++++w +   +   tl+gh
   Q: 309  DAHLSEVSAVCFGPNSSLLATGGADRLILLWNVVGGHLkaNQTLEGAGGSITSVDFDPSGSQLLAATYNKAAQLWKIGEAQSKETLSGH 397
           789999******************************9988899********************************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 398  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLCRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPRCTQVIP--VQGR 480
           ************************************9.666655...5555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iWd+++g+l ++l + +s 
   Q: 481  VTSLSLSHDQLHLLSCSRDDTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSWDGALYIWDVDTGKLESSLRGAHSA 568
           ****************************888833334444555556666.8899*********************************99 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 569  AVNAVAWCYSGSHVVSVDQARKVVLW 594
           999999*************9999999 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

EQGPGVRGSP GPQFSRAIGR ELRRRDRTQK ALFLELVPAY NRLLEKAELL ARFSEKLQPE 60
PNDVTPSVHQ GPWEKESDQG LSPAALRVKW QEEAEGLRLV CGEMAYQVVE KSETLGTLES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCAGGGTC CGGGTGTGAG GGGATCTCCA GGTCCCCAGT TTAGTGCACC GCCTGGTCCA 60
GAGTGTCTGT TTTCGTTGAC TTCGGTCCGG GCGCGGTGGG GTTAAGGAAC ACAGGCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	65.32	0.00e+00	721.00
IUUC-Atr-003073	Amborella trichopoda	32.09	5.00e-27	115.00
IUUC-Ame-011152	Astyanax mexicanus	39.77	3.00e-106	379.00
IUUC-Bta-013118	Bos taurus	88.93	0.00e+00	1048.00
IUUC-Cja-020002	Callithrix jacchus	78.19	0.00e+00	855.00
IUUC-Cfa-020878	Canis familiaris	77.17	0.00e+00	895.00
IUUC-Cpo-022476	Cavia porcellus	75.65	0.00e+00	828.00
IUUC-Csa-024134	Chlorocebus sabaeus	78.80	0.00e+00	861.00
IUUC-Cho-024853	Choloepus hoffmanni	63.65	1.00e-166	579.00
IUUC-Dre-027949	Danio rerio	40.10	6.00e-118	417.00
IUUC-Dno-029683	Dasypus novemcinctus	79.17	0.00e+00	752.00
IUUC-Dor-030897	Dipodomys ordii	77.10	0.00e+00	869.00
IUUC-Ete-032957	Echinops telfairi	93.17	4.00e-128	451.00
IUUC-Eca-033303	Equus caballus	92.28	2.00e-167	581.00
IUUC-Eeu-035336	Erinaceus europaeus	74.50	6.00e-153	534.00
IUUC-Fca-036232	Felis catus	79.77	0.00e+00	973.00
IUUC-Gmo-038880	Gadus morhua	51.40	1.00e-69	257.00
IUUC-Ggo-045130	Gorilla gorilla	89.02	0.00e+00	683.00
IUUC-Hsa-046359	Homo sapiens	80.07	0.00e+00	848.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	77.28	0.00e+00	871.00
IUUC-Lch-050669	Latimeria chalumnae	55.29	2.00e-96	345.00
IUUC-Loc-052789	Lepisosteus oculatus	40.95	2.00e-104	373.00
IUUC-Laf-053699	Loxodonta africana	77.67	0.00e+00	890.00
IUUC-Mcc-055657	Macaca mulatta	74.35	0.00e+00	771.00
IUUC-Meu-056639	Macropus eugenii	45.72	4.00e-108	385.00
IUUC-Mmr-061314	Microcebus murinus	73.62	0.00e+00	783.00
IUUC-Mdo-061841	Monodelphis domestica	62.14	0.00e+00	675.00
IUUC-Mmu-064065	Mus musculus	73.81	0.00e+00	866.00
IUUC-Mac-065022	Musa acuminata	32.08	2.00e-39	155.00
IUUC-Mpu-066742	Mustela putorius furo	88.31	0.00e+00	715.00
IUUC-Mlu-067019	Myotis lucifugus	87.81	0.00e+00	671.00
IUUC-Nle-069037	Nomascus leucogenys	80.23	0.00e+00	887.00
IUUC-Opr-071039	Ochotona princeps	73.70	0.00e+00	849.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.30	5.00e-137	480.00
IUUC-Ocu-074772	Oryctolagus cuniculus	77.36	0.00e+00	790.00
IUUC-Ola-086964	Oryzias latipes	52.26	5.00e-82	297.00
IUUC-Oga-088188	Otolemur garnettii	76.13	0.00e+00	820.00
IUUC-Ptr-091434	Pan troglodytes	77.50	0.00e+00	805.00
IUUC-Pan-091868	Papio anubis	79.22	0.00e+00	852.00
IUUC-Psi-093652	Pelodiscus sinensis	66.18	2.00e-163	568.00
IUUC-Pfo-096960	Poecilia formosa	39.97	7.00e-94	337.00
IUUC-Pab-097776	Pongo abelii	78.91	0.00e+00	831.00
IUUC-Pca-100220	Procavia capensis	59.34	3.00e-168	585.00
IUUC-Ppe-101790	Prunus persica	31.13	3.00e-43	169.00
IUUC-Pva-103135	Pteropus vampyrus	91.81	0.00e+00	715.00
IUUC-Rno-105529	Rattus norvegicus	73.16	0.00e+00	887.00
IUUC-Sha-107062	Sarcophilus harrisii	63.41	0.00e+00	723.00
IUUC-Smo-108983	Selaginella moellendorffii	31.44	7.00e-39	154.00
IUUC-Sly-111009	Solanum lycopersicum	31.13	1.00e-41	164.00
IUUC-Sar-113109	Sorex araneus	68.06	2.00e-135	475.00
IUUC-Ssc-115271	Sus scrofa	79.58	0.00e+00	869.00
IUUC-Ttr-128267	Tursiops truncatus	79.84	0.00e+00	881.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence