iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.90e-17	63.9	34	99
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.70e-06	27.4	133	155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv ++ g  e+++h++vLa+sS++F+a+f ++++es+ + +v++k+++ + +++++ ++Ytg++ +
   Q: 34   TDVSICSGAWEVPCHRSVLASSSPYFKAMFCSHFRESR-EAKVQMKGISSTTLEQVITYVYTGEVHI 99
           7*************************************.*************************976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaa 23
           ++Nclg+ r+A++++c+ Lk++a
   Q: 133  PSNCLGLVRLAEILSCDSLKKKA 155
           89*******************98 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDEELPDGVV FKDHSFSSDL LRQLNGLRQS KILTDVSICS GAWEVPCHRS VLASSSPYFK 60
AMFCSHFRES REAKVQMKGI SSTTLEQVIT YVYTGEVHIS AANVLPLMEA AAMLQYPRVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATACACTG TCTGCCTGCC CGGCAGCCCT TGTACAGAGC TCTAGAAACT GTGAAAGTGC 60
CTGCAGCATA AACAAACCCA GAACTCTCCG AGGACAGAGA ACTTGCCAAC GGAAAGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mmu:268807

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001590	Ailuropoda melanoleuca	82.15	0.00e+00	1021.00
IUUC-Apl-003717	Anas platyrhynchos	68.87	0.00e+00	827.00
IUUC-Aca-005179	Anolis carolinensis	66.67	0.00e+00	852.00
IUUC-Ame-010815	Astyanax mexicanus	55.30	0.00e+00	664.00
IUUC-Bta-013356	Bos taurus	80.90	0.00e+00	990.00
IUUC-Bra-017373	Brassica rapa	23.31	2.00e-09	57.00
IUUC-Cja-019411	Callithrix jacchus	84.14	0.00e+00	1046.00
IUUC-Cfa-020730	Canis familiaris	82.01	0.00e+00	1023.00
IUUC-Cpo-022406	Cavia porcellus	81.41	0.00e+00	986.00
IUUC-Csa-023904	Chlorocebus sabaeus	85.00	0.00e+00	1024.00
IUUC-Dre-028345	Danio rerio	55.65	0.00e+00	677.00
IUUC-Dno-029809	Dasypus novemcinctus	80.34	0.00e+00	1007.00
IUUC-Dor-030675	Dipodomys ordii	79.73	1.00e-142	499.00
IUUC-Dse-031222	Dothistroma septosporum	26.42	4.00e-05	42.00
IUUC-Ete-032256	Echinops telfairi	76.00	0.00e+00	733.00
IUUC-Eeu-034796	Erinaceus europaeus	80.38	0.00e+00	969.00
IUUC-Fca-036124	Felis catus	81.96	0.00e+00	1002.00
IUUC-Fal-036887	Ficedula albicollis	67.30	0.00e+00	819.00
IUUC-Gmo-039299	Gadus morhua	54.74	0.00e+00	643.00
IUUC-Gga-040534	Gallus gallus	68.87	0.00e+00	807.00
IUUC-Gac-041280	Gasterosteus aculeatus	55.69	0.00e+00	676.00
IUUC-Ggo-045490	Gorilla gorilla	84.83	0.00e+00	1028.00
IUUC-Hsa-045672	Homo sapiens	84.31	0.00e+00	1019.00
IUUC-Itr-048640	Ictidomys tridecemlineatus	85.20	0.00e+00	1026.00
IUUC-Lch-050292	Latimeria chalumnae	62.13	0.00e+00	775.00
IUUC-Loc-051771	Lepisosteus oculatus	56.27	0.00e+00	697.00
IUUC-Laf-053679	Loxodonta africana	81.38	0.00e+00	988.00
IUUC-Mcc-055329	Macaca mulatta	85.00	0.00e+00	1021.00
IUUC-Meu-056835	Macropus eugenii	67.23	1.00e-122	433.00
IUUC-Mga-059373	Meleagris gallopavo	69.96	0.00e+00	787.00
IUUC-Mmr-061575	Microcebus murinus	85.94	0.00e+00	1054.00
IUUC-Mdo-062142	Monodelphis domestica	74.31	0.00e+00	896.00
IUUC-Mpu-066730	Mustela putorius furo	82.62	0.00e+00	1005.00
IUUC-Mlu-067782	Myotis lucifugus	83.33	0.00e+00	1028.00
IUUC-Nle-069814	Nomascus leucogenys	84.66	0.00e+00	1013.00
IUUC-Opr-070240	Ochotona princeps	76.89	0.00e+00	712.00
IUUC-Ont-071799	Oreochromis niloticus	55.21	0.00e+00	668.00
IUUC-Oan-072938	Ornithorhynchus anatinus	68.86	0.00e+00	815.00
IUUC-Ocu-074650	Oryctolagus cuniculus	82.44	0.00e+00	1022.00
IUUC-Ola-086611	Oryzias latipes	55.32	0.00e+00	654.00
IUUC-Oga-088645	Otolemur garnettii	83.28	0.00e+00	1040.00
IUUC-Oar-090062	Ovis aries	81.24	0.00e+00	988.00
IUUC-Ptr-091181	Pan troglodytes	78.45	0.00e+00	949.00
IUUC-Pan-092350	Papio anubis	85.00	0.00e+00	1023.00
IUUC-Psi-093340	Pelodiscus sinensis	68.35	0.00e+00	843.00
IUUC-Pma-094164	Petromyzon marinus	41.82	2.00e-110	392.00
IUUC-Pfo-096935	Poecilia formosa	52.60	0.00e+00	652.00
IUUC-Pab-098553	Pongo abelii	84.14	0.00e+00	1045.00
IUUC-Pca-100886	Procavia capensis	81.90	0.00e+00	996.00
IUUC-Pva-102455	Pteropus vampyrus	81.41	0.00e+00	987.00
IUUC-Pte-104106	Pyrenophora teres	25.74	3.00e-10	58.90
IUUC-Pyt-104515	Pyrenophora triticirepentis	25.41	6.00e-08	51.20
IUUC-Rno-105744	Rattus norvegicus	94.49	0.00e+00	1154.00
IUUC-Sha-106885	Sarcophilus harrisii	73.83	0.00e+00	912.00
IUUC-Tgu-116582	Taeniopygia guttata	67.65	0.00e+00	827.00
IUUC-Tru-117998	Takifugu rubripes	54.35	0.00e+00	676.00
IUUC-Tni-120407	Tetraodon nigroviridis	55.41	0.00e+00	638.00
IUUC-Tre-122227	Trichoderma reesei	36.47	4.00e-08	51.20
IUUC-Tvi-122551	Trichoderma virens	24.84	3.00e-07	48.10
IUUC-Tbe-127407	Tupaia belangeri	75.38	0.00e+00	813.00
IUUC-Xtr-132841	Xenopus tropicalis	65.39	0.00e+00	792.00
IUUC-Xma-134084	Xiphophorus maculatus	56.54	0.00e+00	665.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence