iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120433

Ensembl Protein ID

ENSTNIP00000020251.1

UniProt Accession

H3DIA7; H3DIA7_TETNG

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000017116.1	ENSTNIT00000020482.1	ENSTNIP00000020251.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-13	50.9	104	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L+++kGd  ++i  ++++++W+++    ++ rG +P+n+v+ ++
   Q: 104  FVALYDYEARTSDDLSFTKGDRFQII--NNTEGDWWEAR-SITTGRGYIPSNYVAPAD 158
           679***********************..8999******5.888889********9875 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MGCIKSKEEK GSAMKYCPDN SMMADPSSTA AASQMGHYGP DPTQLQNQVP SSSSGNLGVN 60
FNHTITPFGG SSSAMTPFGG VSSSFTGPVS NSFSGAVSSG VTFFVALYDY EARTSDDLSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTGCA TAAAGAGCAA AGAGGAAAAA GGCTCCGCAA TGAAGTACTG TCCGGACAAC 60
TCCATGATGG CGGACCCCAG CTCCACCGCC GCCGCCTCCC AGATGGGCCA TTACGGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	83.94	0.00e+00	920.00
IUUC-Apl-004032	Anas platyrhynchos	83.54	0.00e+00	937.00
IUUC-Aca-004255	Anolis carolinensis	84.63	0.00e+00	949.00
IUUC-Ame-010954	Astyanax mexicanus	87.00	0.00e+00	985.00
IUUC-Bta-013503	Bos taurus	83.70	0.00e+00	911.00
IUUC-Cja-019694	Callithrix jacchus	84.09	0.00e+00	916.00
IUUC-Cfa-020402	Canis familiaris	84.27	0.00e+00	927.00
IUUC-Cpo-022506	Cavia porcellus	84.27	0.00e+00	916.00
IUUC-Csa-023713	Chlorocebus sabaeus	84.45	0.00e+00	920.00
IUUC-Dre-027978	Danio rerio	86.64	0.00e+00	952.00
IUUC-Dno-029897	Dasypus novemcinctus	82.34	0.00e+00	803.00
IUUC-Dor-030202	Dipodomys ordii	91.39	0.00e+00	869.00
IUUC-Eca-034157	Equus caballus	84.27	0.00e+00	927.00
IUUC-Eeu-034950	Erinaceus europaeus	73.13	2.00e-146	511.00
IUUC-Fca-036233	Felis catus	83.91	0.00e+00	944.00
IUUC-Fal-037461	Ficedula albicollis	84.45	0.00e+00	950.00
IUUC-Gmo-038929	Gadus morhua	84.53	0.00e+00	923.00
IUUC-Gga-041107	Gallus gallus	83.73	0.00e+00	938.00
IUUC-Gac-041435	Gasterosteus aculeatus	88.97	0.00e+00	944.00
IUUC-Hsa-047010	Homo sapiens	84.63	0.00e+00	932.00
IUUC-Lch-050239	Latimeria chalumnae	84.99	0.00e+00	962.00
IUUC-Loc-052314	Lepisosteus oculatus	85.92	0.00e+00	922.00
IUUC-Laf-053517	Loxodonta africana	81.61	0.00e+00	906.00
IUUC-Mcc-055626	Macaca mulatta	84.45	0.00e+00	921.00
IUUC-Mga-059310	Meleagris gallopavo	83.73	0.00e+00	938.00
IUUC-Mmr-061652	Microcebus murinus	82.46	0.00e+00	914.00
IUUC-Mdo-062963	Monodelphis domestica	83.18	0.00e+00	922.00
IUUC-Mmu-064128	Mus musculus	84.09	0.00e+00	935.00
IUUC-Mpu-065906	Mustela putorius furo	84.09	0.00e+00	924.00
IUUC-Mlu-067035	Myotis lucifugus	83.63	0.00e+00	919.00
IUUC-Nle-069041	Nomascus leucogenys	80.65	0.00e+00	874.00
IUUC-Opr-070299	Ochotona princeps	76.31	0.00e+00	810.00
IUUC-Ont-072127	Oreochromis niloticus	89.51	0.00e+00	962.00
IUUC-Oan-072997	Ornithorhynchus anatinus	92.17	0.00e+00	885.00
IUUC-Ocu-074171	Oryctolagus cuniculus	83.54	0.00e+00	924.00
IUUC-Ola-086619	Oryzias latipes	89.31	0.00e+00	1028.00
IUUC-Oga-087957	Otolemur garnettii	82.10	0.00e+00	908.00
IUUC-Oar-089670	Ovis aries	82.07	0.00e+00	916.00
IUUC-Ptr-091352	Pan troglodytes	84.63	0.00e+00	932.00
IUUC-Pan-092202	Papio anubis	84.45	0.00e+00	921.00
IUUC-Psi-093310	Pelodiscus sinensis	84.27	0.00e+00	949.00
IUUC-Pma-094232	Petromyzon marinus	84.32	0.00e+00	833.00
IUUC-Pfo-096137	Poecilia formosa	88.61	0.00e+00	1004.00
IUUC-Pab-098301	Pongo abelii	89.96	0.00e+00	888.00
IUUC-Pva-102592	Pteropus vampyrus	78.84	0.00e+00	867.00
IUUC-Rno-105544	Rattus norvegicus	82.82	0.00e+00	914.00
IUUC-Sar-113364	Sorex araneus	80.07	0.00e+00	853.00
IUUC-Tgu-117380	Taeniopygia guttata	84.45	0.00e+00	950.00
IUUC-Tru-117594	Takifugu rubripes	95.48	0.00e+00	1074.00
IUUC-Ttr-128893	Tursiops truncatus	84.27	0.00e+00	927.00
IUUC-Vpa-130060	Vicugna pacos	82.82	0.00e+00	914.00
IUUC-Xtr-132322	Xenopus tropicalis	83.42	0.00e+00	935.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence