iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115420

Ensembl Protein ID

ENSSSCP00000023257.1

UniProt Accession

I3LGR3; I3LGR3_PIG

Genbank Protein ID

ENSSSCP00000023257

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU914290

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000025717.1	ENSSSCT00000027464.1	ENSSSCP00000023257.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-12	48.1	28	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 28   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 87
           9*****************************77.......4566677678****************98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MLDTMEAPGH SRQLLLQLNN QRTKGFLCDV IIVVQNALFR AHKNVLAASS AYLKSLVVHD 60
NLLNLDHDMV SPAVFRLVLD FIYTGRLADG AEAAAAAAVA PGAEPSLGAV LAAASYLQIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGACA CGATGGAGGC TCCCGGCCAC TCGAGGCAGC TGCTGCTGCA GCTCAACAAC 60
CAGCGCACCA AGGGCTTCTT GTGCGACGTG ATCATCGTGG TGCAGAACGC CCTCTTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	87.75	2.00e-150	525.00
IUUC-Aca-004680	Anolis carolinensis	92.86	3.00e-63	236.00
IUUC-Ame-010967	Astyanax mexicanus	61.16	3.00e-94	339.00
IUUC-Bta-013567	Bos taurus	89.96	4.00e-161	561.00
IUUC-Cja-019621	Callithrix jacchus	98.85	2.00e-42	164.00
IUUC-Cfa-020731	Canis familiaris	93.43	0.00e+00	858.00
IUUC-Cpo-021326	Cavia porcellus	92.59	0.00e+00	895.00
IUUC-Csa-023645	Chlorocebus sabaeus	93.85	0.00e+00	847.00
IUUC-Dre-028027	Danio rerio	59.09	1.00e-94	340.00
IUUC-Dno-028900	Dasypus novemcinctus	92.31	0.00e+00	855.00
IUUC-Fal-036980	Ficedula albicollis	61.45	3.00e-116	412.00
IUUC-Gga-040708	Gallus gallus	70.38	4.00e-110	391.00
IUUC-Ggo-044591	Gorilla gorilla	93.81	9.00e-138	483.00
IUUC-Hsa-046769	Homo sapiens	94.13	0.00e+00	834.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	92.90	0.00e+00	872.00
IUUC-Lch-049412	Latimeria chalumnae	53.15	0.00e+00	628.00
IUUC-Loc-051883	Lepisosteus oculatus	63.06	5.00e-94	338.00
IUUC-Laf-053358	Loxodonta africana	88.40	9.00e-165	573.00
IUUC-Mcc-054981	Macaca mulatta	93.85	0.00e+00	847.00
IUUC-Meu-056181	Macropus eugenii	71.65	8.00e-99	353.00
IUUC-Mga-059592	Meleagris gallopavo	73.29	2.00e-107	382.00
IUUC-Mmr-061560	Microcebus murinus	94.41	0.00e+00	847.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	2.00e-91	329.00
IUUC-Mmu-064258	Mus musculus	92.03	0.00e+00	831.00
IUUC-Mpu-065911	Mustela putorius furo	93.43	0.00e+00	857.00
IUUC-Mlu-067575	Myotis lucifugus	76.00	6.00e-132	464.00
IUUC-Ont-072493	Oreochromis niloticus	65.13	2.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	61.90	3.00e-90	325.00
IUUC-Oga-088774	Otolemur garnettii	90.91	0.00e+00	888.00
IUUC-Ptr-090491	Pan troglodytes	95.90	1.00e-125	442.00
IUUC-Pma-094179	Petromyzon marinus	70.51	3.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.31	5.00e-89	322.00
IUUC-Pab-098488	Pongo abelii	90.06	1.00e-170	592.00
IUUC-Pca-100667	Procavia capensis	95.77	3.00e-143	502.00
IUUC-Pva-102421	Pteropus vampyrus	93.85	0.00e+00	840.00
IUUC-Rno-105528	Rattus norvegicus	89.20	0.00e+00	780.00
IUUC-Sar-113478	Sorex araneus	98.76	1.00e-119	423.00
IUUC-Tgu-116642	Taeniopygia guttata	71.34	4.00e-111	395.00
IUUC-Tru-118583	Takifugu rubripes	61.83	1.00e-84	307.00
IUUC-Xtr-132210	Xenopus tropicalis	58.92	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence