iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-15	55.6	55	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           s+e+v++ly++++q+d++L lk Gd+v+++  e+ + +W kg    +g+ G+fP+n+v+ 
   Q: 55   SLEYVEALYQFDPQQDGDLGLKPGDKVQLL--EKLSPEWYKG--SCNGRTGIFPANYVKP 110
           5789**************************..999*******..9*************96 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.

Protein Sequence
(Fasta)

MSASLINRSL TNIRTELDFL KGSNVISNDV YDQINKSLPA KWDPANAPRN ASPASLEYVE 60
ALYQFDPQQD GDLGLKPGDK VQLLEKLSPE WYKGSCNGRT GIFPANYVKP AFSGSNGPSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGCTT CATTGATTAA TCGTTCCTTA ACAAACATTA GGACAGAACT GGATTTTCTA 60
AAAGGGTCAA ATGTCATTTC AAATGACGTT TACGATCAAA TAAATAAGAG CTTGCCGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0832--Ubl conjugation

Interpro

IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0034316--P:negative regulation of Arp2/3 complex-mediated actin nucleation

KEGG

sce:YPR154W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001345	Ailuropoda melanoleuca	51.85	2.00e-16	76.60
IUUC-Apl-003322	Anas platyrhynchos	53.70	2.00e-16	77.00
IUUC-Aca-005193	Anolis carolinensis	53.70	2.00e-16	77.00
IUUC-Ago-007965	Ashbya gossypii	55.04	4.00e-33	132.00
IUUC-Ame-010929	Astyanax mexicanus	52.54	6.00e-17	78.60
IUUC-Bta-012932	Bos taurus	51.85	2.00e-16	76.60
IUUC-Cel-018665	Caenorhabditis elegans	43.28	2.00e-13	67.00
IUUC-Cja-019225	Callithrix jacchus	51.85	2.00e-16	76.60
IUUC-Cfa-020887	Canis familiaris	51.85	2.00e-16	76.60
IUUC-Cpo-022488	Cavia porcellus	51.85	2.00e-16	76.60
IUUC-Csa-023326	Chlorocebus sabaeus	51.85	2.00e-16	76.60
IUUC-Cho-024953	Choloepus hoffmanni	51.85	1.00e-16	77.40
IUUC-Dre-028095	Danio rerio	47.83	2.00e-17	80.10
IUUC-Dno-029187	Dasypus novemcinctus	51.85	2.00e-16	77.00
IUUC-Dor-030763	Dipodomys ordii	51.85	2.00e-16	76.60
IUUC-Ete-032354	Echinops telfairi	53.70	2.00e-16	77.00
IUUC-Eca-033222	Equus caballus	51.85	2.00e-16	76.60
IUUC-Eeu-034513	Erinaceus europaeus	51.85	3.00e-16	76.30
IUUC-Fca-036294	Felis catus	51.85	2.00e-16	76.60
IUUC-Fal-037130	Ficedula albicollis	53.70	5.00e-16	75.50
IUUC-Gmo-039546	Gadus morhua	51.85	5.00e-16	75.50
IUUC-Gga-041139	Gallus gallus	53.70	2.00e-16	77.00
IUUC-Gac-041968	Gasterosteus aculeatus	53.70	2.00e-16	77.00
IUUC-Ggo-044562	Gorilla gorilla	51.85	2.00e-16	76.60
IUUC-Hsa-046730	Homo sapiens	51.85	2.00e-16	76.60
IUUC-Hvu-047839	Hordeum vulgare	35.96	1.00e-07	47.40
IUUC-Itr-049025	Ictidomys tridecemlineatus	51.85	2.00e-16	76.60
IUUC-Kpa-049104	Komagataella pastoris	40.00	2.00e-36	143.00
IUUC-Lch-050230	Latimeria chalumnae	55.56	6.00e-17	79.30
IUUC-Loc-052723	Lepisosteus oculatus	53.70	2.00e-16	76.60
IUUC-Laf-053774	Loxodonta africana	53.70	1.00e-16	77.80
IUUC-Mcc-054603	Macaca mulatta	51.85	2.00e-16	76.60
IUUC-Meu-056173	Macropus eugenii	55.56	4.00e-17	79.30
IUUC-Mga-059950	Meleagris gallopavo	53.70	2.00e-16	77.00
IUUC-Mvi-060542	Microbotryum violaceum	48.98	6.00e-11	58.50
IUUC-Mmr-060878	Microcebus murinus	51.85	2.00e-16	76.60
IUUC-Mdo-062454	Monodelphis domestica	55.56	5.00e-17	79.00
IUUC-Mmu-063913	Mus musculus	51.85	2.00e-16	76.60
IUUC-Mpu-066125	Mustela putorius furo	51.85	2.00e-16	76.60
IUUC-Mlu-068007	Myotis lucifugus	51.85	2.00e-16	76.60
IUUC-Nle-069101	Nomascus leucogenys	51.85	2.00e-16	76.60
IUUC-Opr-071075	Ochotona princeps	51.85	2.00e-16	76.60
IUUC-Ont-072253	Oreochromis niloticus	53.70	2.00e-16	76.60
IUUC-Ocu-074583	Oryctolagus cuniculus	51.85	2.00e-16	76.60
IUUC-Ola-086586	Oryzias latipes	51.67	6.00e-16	75.90
IUUC-Oga-089047	Otolemur garnettii	51.85	2.00e-16	76.60
IUUC-Ptr-090678	Pan troglodytes	51.85	2.00e-16	76.60
IUUC-Pan-092090	Papio anubis	51.85	2.00e-16	76.60
IUUC-Psi-093765	Pelodiscus sinensis	53.70	2.00e-16	77.00
IUUC-Pma-094650	Petromyzon marinus	50.94	1.00e-14	70.90
IUUC-Pno-095097	Phaeosphaeria nodorum	51.67	4.00e-12	62.80
IUUC-Ppa-095161	Physcomitrella patens	36.36	1.00e-07	48.50
IUUC-Pfo-096131	Poecilia formosa	53.70	2.00e-16	77.00
IUUC-Pab-098709	Pongo abelii	51.85	2.00e-16	76.60
IUUC-Pca-100581	Procavia capensis	53.70	1.00e-16	77.80
IUUC-Pva-103066	Pteropus vampyrus	51.85	2.00e-16	76.60
IUUC-Rno-105224	Rattus norvegicus	51.85	2.00e-16	76.60
IUUC-Sha-107247	Sarcophilus harrisii	55.56	5.00e-17	78.60
IUUC-Sar-113277	Sorex araneus	51.85	1.00e-16	77.40
IUUC-Ssc-115478	Sus scrofa	51.85	2.00e-16	76.60
IUUC-Tgu-117479	Taeniopygia guttata	53.70	5.00e-16	75.50
IUUC-Tru-118451	Takifugu rubripes	56.60	6.00e-12	62.00
IUUC-Tbe-128097	Tupaia belangeri	51.85	2.00e-16	76.60
IUUC-Vpa-130754	Vicugna pacos	51.85	2.00e-16	76.60
IUUC-Xtr-132275	Xenopus tropicalis	53.70	3.00e-16	76.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence