iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069748

Ensembl Protein ID

ENSNLEP00000012736.1

UniProt Accession

G1RHN5; G1RHN5_NOMLE

Genbank Protein ID

ENSNLEP00000012736

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01128584

Gene Name

SHARPIN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000010468.1	ENSNLET00000013362.1	ENSNLEP00000012736.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	3.60e-12	45.9	232	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlk......vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdg 64
           ++  +      v+p++tVa L+e+++++lg+pp+ qr+++ G++L  + ++La+yg++++
   Q: 232  STASSvhvilqVHPHCTVAALQEQVFSELGFPPAVQRWVI-GRCLcVPERSLASYGVQQD 290
           444443333357****************************.**************88754 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAPPAGGAAA ASDLGSAAVL LAVHAAVRPL GAGLDTEAQL RRLQLSADPE RPGRFRLELL 60
GAGPGAVNLE WPLESVSYTI RGPTQHELQP PPGGPGTLSL HFLNPQEAQR WAVLVRGATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCCTCGGACT TGGGCTCGGC CGCAGTGCTC 60
TTGGCTGTGC ACGCCGCGGT GAGGCCGCTG GGCGCCGGGC TAGACACCGA GGCACAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR031912--Sharpin_PH
IPR029071--Ubiquitin-rel_dom

Pfam

PF16764--Sharpin_PH

Gene Ontology

GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0097039--P:protein linear polyubiquitination
GO:2000348--P:regulation of CD40 signaling pathway
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000111	Aegilops tauschii	38.24	2.30e-02	32.70
IUUC-Aml-001223	Ailuropoda melanoleuca	80.39	2.00e-112	398.00
IUUC-Apl-004151	Anas platyrhynchos	65.96	3.00e-17	79.30
IUUC-Ago-007835	Ashbya gossypii	39.13	7.70e-01	27.70
IUUC-Ang-009713	Aspergillus niger	32.79	1.90e-02	33.50
IUUC-Bta-012948	Bos taurus	82.22	4.00e-123	434.00
IUUC-Cel-018155	Caenorhabditis elegans	31.76	7.20e-02	29.30
IUUC-Cja-019031	Callithrix jacchus	90.10	2.00e-121	429.00
IUUC-Cfa-020863	Canis familiaris	74.84	7.00e-89	320.00
IUUC-Cpo-022499	Cavia porcellus	75.99	3.00e-111	394.00
IUUC-Csa-023641	Chlorocebus sabaeus	92.36	2.00e-134	471.00
IUUC-Dno-029459	Dasypus novemcinctus	64.00	3.00e-58	218.00
IUUC-Dor-030914	Dipodomys ordii	63.69	2.00e-85	308.00
IUUC-Ete-032940	Echinops telfairi	70.19	4.00e-99	354.00
IUUC-Eca-033537	Equus caballus	80.46	2.00e-116	411.00
IUUC-Eeu-035176	Erinaceus europaeus	69.15	2.00e-63	235.00
IUUC-Fca-035971	Felis catus	79.43	2.00e-105	375.00
IUUC-Gmo-039219	Gadus morhua	41.33	2.00e-40	159.00
IUUC-Ggo-044678	Gorilla gorilla	92.05	1.00e-142	498.00
IUUC-Hsa-046578	Homo sapiens	94.98	1.00e-148	518.00
IUUC-Itr-047913	Ictidomys tridecemlineatus	74.92	6.00e-112	397.00
IUUC-Mcc-055686	Macaca mulatta	93.57	1.00e-129	456.00
IUUC-Meu-055912	Macropus eugenii	52.94	3.00e-59	221.00
IUUC-Mmr-060584	Microcebus murinus	80.51	2.00e-119	422.00
IUUC-Mdo-062191	Monodelphis domestica	54.82	5.00e-66	244.00
IUUC-Mmu-063740	Mus musculus	70.59	4.00e-95	341.00
IUUC-Mpu-066878	Mustela putorius furo	78.05	7.00e-106	377.00
IUUC-Mlu-067878	Myotis lucifugus	80.07	1.00e-115	409.00
IUUC-Ont-072270	Oreochromis niloticus	40.07	5.00e-40	158.00
IUUC-Oga-088300	Otolemur garnettii	80.98	4.00e-126	444.00
IUUC-Oar-089549	Ovis aries	80.94	2.00e-122	432.00
IUUC-Ptr-090961	Pan troglodytes	95.65	1.00e-149	521.00
IUUC-Pan-092687	Papio anubis	94.00	2.00e-139	488.00
IUUC-Pfo-096865	Poecilia formosa	38.11	6.00e-29	121.00
IUUC-Pab-097872	Pongo abelii	96.05	1.00e-148	519.00
IUUC-Pca-100363	Procavia capensis	71.30	2.00e-69	255.00
IUUC-Pva-102595	Pteropus vampyrus	79.26	3.00e-118	418.00
IUUC-Rno-105856	Rattus norvegicus	72.43	2.00e-97	348.00
IUUC-Sha-106838	Sarcophilus harrisii	54.55	4.00e-57	215.00
IUUC-Sar-113611	Sorex araneus	79.49	5.00e-27	114.00
IUUC-Ssc-116263	Sus scrofa	76.36	2.00e-115	408.00
IUUC-Tru-118089	Takifugu rubripes	41.53	4.00e-44	172.00
IUUC-Tni-120004	Tetraodon nigroviridis	41.53	1.00e-33	137.00
IUUC-Tbe-127471	Tupaia belangeri	72.78	2.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence