iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050096

Ensembl Protein ID

ENSLACP00000010943.1

UniProt Accession

H3AMS2; H3AMS2_LATCH

Genbank Protein ID

ENSLACP00000010943

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01144818

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000009628.1	ENSLACT00000011024.1	ENSLACP00000010943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-10	41.6	621	677

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v + y ++a ++ e +l+ G  v+++   +++ + +W     e +g+rG +P+nF ++
   Q: 621  QVFAGYAFTARSSHEVSLQPGQPVTIVepYDKKGNLEWNLV--EVNGQRGYVPSNFLVR 677
           56778**********************55566778899977..9************765 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MEEHQYDTPN SEELELIYAA TEDLSTEKKN QSQTFAIEEL ISTEETYLSS LELCTGGIYE 60
HLSEKQLPNL DLDGLYGNIK DVIEVSRNFL TKLKTARTQK ADQLLLISNA FLDLKQDMEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGC ACCAGTATGA CACTCCAAAC TCAGAGGAAC TTGAGCTCAT TTATGCAGCA 60
ACTGAAGATC TCAGTACTGA AAAGAAGAAC CAAAGTCAAA CATTTGCCAT TGAAGAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2

SMART

SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003698	Anas platyrhynchos	30.12	4.00e-79	289.00
IUUC-Ame-011907	Astyanax mexicanus	44.81	2.00e-158	552.00
IUUC-Bta-012848	Bos taurus	45.29	1.00e-156	546.00
IUUC-Cfa-021281	Canis familiaris	44.67	1.00e-158	553.00
IUUC-Csa-023043	Chlorocebus sabaeus	46.90	4.00e-166	578.00
IUUC-Dre-028496	Danio rerio	44.99	4.00e-157	548.00
IUUC-Ggo-044900	Gorilla gorilla	45.73	3.00e-164	571.00
IUUC-Hsa-045684	Homo sapiens	46.46	5.00e-168	584.00
IUUC-Loc-051937	Lepisosteus oculatus	44.51	1.00e-158	553.00
IUUC-Mcc-054950	Macaca mulatta	46.32	5.00e-164	571.00
IUUC-Meu-056383	Macropus eugenii	48.04	3.00e-103	369.00
IUUC-Mdo-062021	Monodelphis domestica	47.02	2.00e-157	549.00
IUUC-Mmu-064186	Mus musculus	46.35	2.00e-151	529.00
IUUC-Ptr-090508	Pan troglodytes	45.78	2.00e-165	575.00
IUUC-Pan-092517	Papio anubis	46.14	4.00e-161	561.00
IUUC-Pfo-096703	Poecilia formosa	42.12	2.00e-139	489.00
IUUC-Pab-098542	Pongo abelii	46.02	5.00e-164	571.00
IUUC-Rno-105455	Rattus norvegicus	48.32	2.00e-164	572.00
IUUC-Sha-106562	Sarcophilus harrisii	46.74	5.00e-161	561.00
IUUC-Ttr-128242	Tursiops truncatus	45.74	1.00e-152	533.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence