iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062021

Ensembl Protein ID

ENSMODP00000012387.3

UniProt Accession

F6VCA2; F6VCA2_MONDO

Protein Name

Uncharacterized protein

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000009895.3	ENSMODT00000012612.3	ENSMODP00000012387.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.50e-11	41.6	609	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v + y++ a ++ e +l++G  v+v+  ++++ + +W     e +g+rG +P+nF + 
   Q: 609  QVVAAYPFVARSNYEVSLQAGQSVTVLerQDKKGNPEWSLV--EVNGQRGYVPSNFLVC 665
           78999**********************88889999***977..9************875 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MASYLESEPP SPGESSGDES QGVEATRICE KMKLNQRLAA KELVNTEAKY VHNLQLCASD 60
IRSHLHELPQ GDLDVIFSNI DDIIKVNSRF LKDLEKAGSE EEQISLLGNL FLEFQEEMEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGGTCCT GTCCCGACTG TCAGCCTGCT TCTGCCTGCT CCGTGGGCTG GCCATGGAGA 60
AACATTCAGT TGCTTGTTAA TTTTTTTTTT TCCAGAGACT GAGACTACCT TGAGCAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

KEGG

mdo:100028783

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011907	Astyanax mexicanus	41.51	2.00e-138	486.00
IUUC-Bta-012848	Bos taurus	69.35	0.00e+00	875.00
IUUC-Cfa-021281	Canis familiaris	65.88	0.00e+00	874.00
IUUC-Csa-023043	Chlorocebus sabaeus	66.52	0.00e+00	863.00
IUUC-Dre-028496	Danio rerio	41.14	9.00e-137	480.00
IUUC-Ggo-044900	Gorilla gorilla	65.74	0.00e+00	881.00
IUUC-Hsa-045684	Homo sapiens	65.93	0.00e+00	885.00
IUUC-Lch-050096	Latimeria chalumnae	47.02	7.00e-164	570.00
IUUC-Loc-051937	Lepisosteus oculatus	42.90	8.00e-137	480.00
IUUC-Mcc-054950	Macaca mulatta	68.21	0.00e+00	853.00
IUUC-Meu-056383	Macropus eugenii	83.48	0.00e+00	732.00
IUUC-Mmu-064186	Mus musculus	62.61	0.00e+00	823.00
IUUC-Ptr-090508	Pan troglodytes	65.88	0.00e+00	884.00
IUUC-Pan-092517	Papio anubis	65.88	0.00e+00	854.00
IUUC-Pfo-096703	Poecilia formosa	39.29	1.00e-124	441.00
IUUC-Pab-098542	Pongo abelii	66.03	0.00e+00	882.00
IUUC-Rno-105455	Rattus norvegicus	65.39	0.00e+00	856.00
IUUC-Sha-106562	Sarcophilus harrisii	86.59	0.00e+00	1174.00
IUUC-Ttr-128242	Tursiops truncatus	68.05	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence