iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005062

UUCD1 version

UUC-AnC-00918

Ensembl Protein ID

ENSACAP00000008145.1

UniProt Accession

G1KHM0; G1KHM0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE2G2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008283.1	ENSACAT00000008318.1	ENSACAP00000008145.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.50e-48	163.3	8	156

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rl+ e+k+l+ +ppegi+a+p++e++++ewe+li+Gpedt++e gvF + ++fp dYP++PPk++f+ ++fhPn+y++G+vC+sil+  
   Q: 8    RLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEYGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHap 96
           99************************************************************************************889 PP
   S: 88   .........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
                    ++e+Wsp++sve +lls++s+laepn es++n++a+++++++re+++k++++
   Q: 97   gddpmgyesSAERWSPVQSVE-ILLSVVSMLAEPNDESGANVDASKMWREDREQFNKIAKQ 156
           9999999999*********96.9**********************************9975 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAGTALKRLM AEYKQLTLNP PEGIVAGPMN EENFFEWEAL IMGPEDTCFE YGVFPAILSF 60
PLDYPLSPPK MRFTCEMFHP NIYPDGRVCI SILHAPGDDP MGYESSAERW SPVQSVEILL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGTA CCGCGCTCAA GCGACTCATG GCGGAGTATA AACGTGAGCG GAGACGGGAG 60
ACAAGGCAGG GGCGTGGGAT GGGGGAAGGC CGCAGCCAGA AAGACCTTAT AATACAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0035458--P:cellular response to interferon-beta
GO:1904153--P:negative regulation of retrograde protein transport, ER to cytosol
GO:0070936--P:protein K48-linked ubiquitination
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002172	Ailuropoda melanoleuca	90.45	7.00e-83	298.00
IUUC-Apl-003761	Anas platyrhynchos	94.44	6.00e-88	315.00
IUUC-Ago-007853	Ashbya gossypii	61.21	3.00e-56	210.00
IUUC-Acl-008080	Aspergillus clavatus	62.65	2.00e-57	214.00
IUUC-Afl-008478	Aspergillus flavus	62.05	2.00e-56	211.00
IUUC-Afu-009051	Aspergillus fumigatus	62.65	2.00e-57	214.00
IUUC-Ani-009271	Aspergillus nidulans	60.84	1.00e-50	191.00
IUUC-Ang-009748	Aspergillus niger	63.25	1.00e-57	214.00
IUUC-Aor-010228	Aspergillus oryzae	62.05	2.00e-56	211.00
IUUC-Ate-010293	Aspergillus terreus	62.65	1.00e-57	214.00
IUUC-Ame-011698	Astyanax mexicanus	93.94	4.00e-90	322.00
IUUC-Bgr-012226	Blumeria graminis	60.98	9.00e-56	208.00
IUUC-Bta-013277	Bos taurus	95.93	4.00e-67	245.00
IUUC-Bci-013676	Botrytis cinerea	60.98	3.00e-55	206.00
IUUC-Cel-018676	Caenorhabditis elegans	76.97	3.00e-73	266.00
IUUC-Cja-019767	Callithrix jacchus	96.36	9.00e-92	328.00
IUUC-Cfa-020047	Canis familiaris	93.94	6.00e-91	325.00
IUUC-Cpo-021507	Cavia porcellus	96.97	4.00e-92	329.00
IUUC-Csa-023745	Chlorocebus sabaeus	90.85	6.00e-85	305.00
IUUC-Cho-024667	Choloepus hoffmanni	63.06	3.00e-50	190.00
IUUC-Cin-025310	Ciona intestinalis	80.61	3.00e-77	280.00
IUUC-Csv-025961	Ciona savignyi	80.00	2.00e-76	277.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	64.81	2.00e-59	221.00
IUUC-Cne-026903	Cryptococcus neoformans	55.76	1.00e-45	175.00
IUUC-Dre-027900	Danio rerio	94.55	3.00e-90	323.00
IUUC-Dno-029688	Dasypus novemcinctus	90.91	2.00e-85	307.00
IUUC-Dor-030374	Dipodomys ordii	63.40	3.00e-49	186.00
IUUC-Dse-031253	Dothistroma septosporum	63.64	1.00e-60	224.00
IUUC-Dme-031849	Drosophila melanogaster	82.42	3.00e-79	286.00
IUUC-Ete-033010	Echinops telfairi	96.97	1.00e-90	324.00
IUUC-Eca-033294	Equus caballus	92.99	2.00e-84	303.00
IUUC-Eeu-034947	Erinaceus europaeus	70.87	9.00e-46	174.00
IUUC-Fca-036442	Felis catus	93.43	3.00e-74	270.00
IUUC-Fal-037188	Ficedula albicollis	97.39	7.00e-86	308.00
IUUC-Fox-037762	Fusarium oxysporum	62.42	1.00e-58	218.00
IUUC-Fso-038181	Fusarium solani	61.82	7.00e-58	215.00
IUUC-Gmo-038663	Gadus morhua	91.52	8.00e-88	315.00
IUUC-Ggr-039808	Gaeumannomyces graminis	64.81	5.00e-60	223.00
IUUC-Gga-040355	Gallus gallus	99.39	2.00e-94	337.00
IUUC-Gac-041847	Gasterosteus aculeatus	91.52	5.00e-88	315.00
IUUC-Ggo-045202	Gorilla gorilla	97.58	1.00e-92	331.00
IUUC-Hsa-046369	Homo sapiens	97.58	1.00e-92	331.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	96.36	6.00e-92	328.00
IUUC-Kpa-049317	Komagataella pastoris	62.58	2.00e-57	214.00
IUUC-Lch-049596	Latimeria chalumnae	86.06	9.00e-81	291.00
IUUC-Loc-052346	Lepisosteus oculatus	93.50	1.00e-64	237.00
IUUC-Lma-053126	Leptosphaeria maculans	68.94	1.00e-50	191.00
IUUC-Laf-054560	Loxodonta africana	90.85	2.00e-84	303.00
IUUC-Mcc-055172	Macaca mulatta	97.58	1.00e-92	331.00
IUUC-Meu-056891	Macropus eugenii	92.99	3.00e-84	303.00
IUUC-Mor-057260	Magnaporthe oryzae	63.58	6.00e-59	219.00
IUUC-Mpo-057468	Magnaporthe poae	65.43	1.00e-60	224.00
IUUC-Mla-059084	Melampsora laricipopulina	58.72	2.00e-54	204.00
IUUC-Mga-059939	Meleagris gallopavo	91.46	3.00e-86	310.00
IUUC-Mvi-060514	Microbotryum violaceum	64.85	1.00e-57	214.00
IUUC-Mmr-061029	Microcebus murinus	91.67	8.00e-85	305.00
IUUC-Mdo-061820	Monodelphis domestica	96.36	9.00e-92	328.00
IUUC-Mmu-063123	Mus musculus	97.58	1.00e-92	331.00
IUUC-Mpu-065866	Mustela putorius furo	86.67	3.00e-83	300.00
IUUC-Mlu-067220	Myotis lucifugus	91.88	2.00e-84	303.00
IUUC-Nfi-068395	Neosartorya fischeri	62.65	2.00e-57	214.00
IUUC-Ncr-068623	Neurospora crassa	63.58	3.00e-57	213.00
IUUC-Nle-070007	Nomascus leucogenys	97.58	1.00e-92	331.00
IUUC-Opr-071095	Ochotona princeps	98.23	4.00e-62	229.00
IUUC-Ont-071736	Oreochromis niloticus	93.94	9.00e-90	321.00
IUUC-Oan-073475	Ornithorhynchus anatinus	92.99	9.00e-84	301.00
IUUC-Ocu-074820	Oryctolagus cuniculus	93.55	5.00e-84	302.00
IUUC-Ola-087571	Oryzias latipes	93.33	2.00e-89	320.00
IUUC-Oar-089706	Ovis aries	96.97	2.00e-92	330.00
IUUC-Ptr-090798	Pan troglodytes	97.58	1.00e-92	331.00
IUUC-Pan-091967	Papio anubis	97.58	1.00e-92	331.00
IUUC-Psi-093524	Pelodiscus sinensis	95.36	2.00e-83	300.00
IUUC-Pma-094602	Petromyzon marinus	90.65	7.00e-72	261.00
IUUC-Pno-094979	Phaeosphaeria nodorum	65.45	6.00e-62	229.00
IUUC-Pfo-097330	Poecilia formosa	93.33	8.00e-89	318.00
IUUC-Pab-098225	Pongo abelii	96.97	5.00e-92	328.00
IUUC-Pca-101040	Procavia capensis	95.42	7.00e-84	301.00
IUUC-Pva-102507	Pteropus vampyrus	80.89	2.00e-69	254.00
IUUC-Pgr-103674	Puccinia graminis	59.65	2.00e-54	204.00
IUUC-Ptt-103840	Puccinia triticina	58.48	1.00e-53	201.00
IUUC-Pte-104389	Pyrenophora teres	67.27	3.00e-64	237.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	66.67	2.00e-63	234.00
IUUC-Rno-105228	Rattus norvegicus	97.58	1.00e-92	331.00
IUUC-Sce-106233	Saccharomyces cerevisiae	61.21	6.00e-54	202.00
IUUC-Sha-107274	Sarcophilus harrisii	89.16	7.00e-85	305.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	68.94	1.00e-65	241.00
IUUC-Spo-108269	Schizosaccharomyces pombe	68.32	5.00e-65	239.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	61.59	2.00e-56	211.00
IUUC-Sre-114952	Sporisorium reilianum	63.64	9.00e-56	208.00
IUUC-Ssc-115365	Sus scrofa	90.30	4.00e-84	303.00
IUUC-Tgu-116816	Taeniopygia guttata	99.39	2.00e-94	337.00
IUUC-Tru-118547	Takifugu rubripes	79.82	5.00e-49	185.00
IUUC-Tni-120278	Tetraodon nigroviridis	90.36	6.00e-86	308.00
IUUC-Tre-122131	Trichoderma reesei	63.58	1.00e-58	218.00
IUUC-Tvi-122669	Trichoderma virens	63.58	6.00e-59	219.00
IUUC-Tme-127052	Tuber melanosporum	67.48	1.00e-64	238.00
IUUC-Tbe-127792	Tupaia belangeri	97.58	1.00e-92	331.00
IUUC-Ttr-128619	Tursiops truncatus	93.33	1.00e-62	231.00
IUUC-Uma-129587	Ustilago maydis	63.03	2.00e-55	207.00
IUUC-Vda-129914	Verticillium dahliae	62.96	5.00e-58	216.00
IUUC-Xtr-132450	Xenopus tropicalis	96.97	4.00e-92	329.00
IUUC-Xma-133016	Xiphophorus maculatus	93.94	6.00e-89	318.00
IUUC-Yli-134379	Yarrowia lipolytica	70.99	2.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence