iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089878

Ensembl Protein ID

ENSOARP00000005936.1

UniProt Accession

W5P682; W5P682_SHEEP

Genbank Protein ID

ENSOARP00000005936

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01115207

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005533.1	ENSOART00000006026.1	ENSOARP00000005936.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.90e-10	40.7	582	619
ULD/UDP/UBQ/UBQ_PIM	2.20e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 582  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 619
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGSAAA QGPASTQAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ATGGCGAGAG CAGCGGCCCC CCGCGCCCCT CCCGCGGCTC TGCTGCGGCC 60
CAAGGCCCAG CCTCTACCCA GGCCGAGCCC AAAATCATCA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

oas:101114677

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ani-009418	Aspergillus nidulans	25.44	8.00e-09	55.10
IUUC-Bta-013571	Bos taurus	99.68	0.00e+00	774.00
IUUC-Cfa-020799	Canis familiaris	98.20	0.00e+00	638.00
IUUC-Cpo-022093	Cavia porcellus	96.30	2.00e-173	602.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	96.90	0.00e+00	749.00
IUUC-Cho-024552	Choloepus hoffmanni	92.58	8.00e-173	599.00
IUUC-Csv-026009	Ciona savignyi	48.63	6.00e-88	318.00
IUUC-Cne-026833	Cryptococcus neoformans	27.46	1.00e-14	74.30
IUUC-Dno-029647	Dasypus novemcinctus	93.24	0.00e+00	627.00
IUUC-Ete-033071	Echinops telfairi	87.50	0.00e+00	731.00
IUUC-Eeu-034727	Erinaceus europaeus	93.60	0.00e+00	727.00
IUUC-Fca-035803	Felis catus	98.65	4.00e-180	624.00
IUUC-Fso-038204	Fusarium solani	42.25	2.00e-08	53.90
IUUC-Hsa-046768	Homo sapiens	97.52	1.00e-176	613.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	5.00e-09	53.10
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.48	9.00e-173	600.00
IUUC-Mor-057194	Magnaporthe oryzae	48.00	2.00e-07	50.10
IUUC-Mla-058987	Melampsora laricipopulina	53.49	4.00e-07	49.30
IUUC-Mvi-060466	Microbotryum violaceum	54.76	3.00e-08	53.10
IUUC-Mmr-061605	Microcebus murinus	95.07	3.00e-170	591.00
IUUC-Mpu-066474	Mustela putorius furo	98.20	4.00e-180	624.00
IUUC-Mlu-067252	Myotis lucifugus	87.87	1.00e-164	573.00
IUUC-Ncr-068732	Neurospora crassa	48.98	2.00e-07	50.40
IUUC-Nle-069038	Nomascus leucogenys	97.07	0.00e+00	748.00
IUUC-Oga-088005	Otolemur garnettii	97.07	1.00e-176	612.00
IUUC-Ptr-090781	Pan troglodytes	97.52	3.00e-177	615.00
IUUC-Pab-097891	Pongo abelii	97.74	5.00e-177	614.00
IUUC-Pca-100227	Procavia capensis	95.36	8.00e-94	337.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Sce-106332	Saccharomyces cerevisiae	33.64	4.00e-16	79.00
IUUC-Sre-115081	Sporisorium reilianum	26.09	9.00e-12	64.70
IUUC-Tsy-119008	Tarsius syrichta	94.91	2.00e-172	599.00
IUUC-Uma-129639	Ustilago maydis	27.16	2.00e-11	63.50
IUUC-Vda-129991	Verticillium dahliae	46.15	7.00e-07	48.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence