iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120843

Ensembl Protein ID

ENSTNIP00000021436.1

UniProt Accession

H3DLN8; H3DLN8_TETNG

Protein Name

Tyrosine-protein kinase

Gene Name

SRC (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000018270.1	ENSTNIT00000021671.1	ENSTNIP00000021436.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-13	50.5	96	150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +Lt++kGd ++++  ++++++W+ + + ++g +G +P+n+v+ 
   Q: 96   TFVALYDYESRTASDLTFRKGDRLQIV--NNTEGDWWLARSLTTGESGYIPSNYVAP 150
           5789***********************..8999*********************975 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MGAGKSKPKE PGQRSMSLDG TIGTGSDSGH FHHLGPAQQT QTPNRSPAVG TGRRGHPGQH 60
HQAPTNTPEL ALFGGVDHTC TITSPQRGPL SGGVTTFVAL YDYESRTASD LTFRKGDRLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGCGG GCAAGAGCAA GCCCAAGGAG CCAGGCCAGC GCTCCATGAG CCTGGACGGC 60
ACCATCGGCA CCGGCTCGGA CAGCGGCCAT TTCCACCACC TGGGCCCCGC CCAGCAGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001713	Ailuropoda melanoleuca	80.76	0.00e+00	902.00
IUUC-Aca-004237	Anolis carolinensis	81.47	0.00e+00	908.00
IUUC-Ame-011887	Astyanax mexicanus	87.02	0.00e+00	959.00
IUUC-Bta-012982	Bos taurus	82.23	0.00e+00	912.00
IUUC-Cja-019995	Callithrix jacchus	80.76	0.00e+00	904.00
IUUC-Cfa-020060	Canis familiaris	81.65	0.00e+00	912.00
IUUC-Cpo-021557	Cavia porcellus	80.92	0.00e+00	898.00
IUUC-Csa-023711	Chlorocebus sabaeus	80.58	0.00e+00	901.00
IUUC-Cin-025390	Ciona intestinalis	68.66	0.00e+00	652.00
IUUC-Csv-026029	Ciona savignyi	69.28	8.00e-179	619.00
IUUC-Dre-028491	Danio rerio	85.87	0.00e+00	919.00
IUUC-Dno-029651	Dasypus novemcinctus	78.61	0.00e+00	884.00
IUUC-Ete-033170	Echinops telfairi	86.90	0.00e+00	828.00
IUUC-Eca-033970	Equus caballus	79.45	0.00e+00	874.00
IUUC-Fca-036113	Felis catus	81.65	0.00e+00	912.00
IUUC-Fal-036785	Ficedula albicollis	80.58	0.00e+00	900.00
IUUC-Gga-040899	Gallus gallus	81.87	0.00e+00	908.00
IUUC-Gac-041976	Gasterosteus aculeatus	95.05	0.00e+00	1063.00
IUUC-Hsa-046192	Homo sapiens	80.98	0.00e+00	901.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	80.94	0.00e+00	901.00
IUUC-Lch-049892	Latimeria chalumnae	81.28	0.00e+00	912.00
IUUC-Loc-052812	Lepisosteus oculatus	87.07	0.00e+00	951.00
IUUC-Laf-053977	Loxodonta africana	80.94	0.00e+00	904.00
IUUC-Mcc-055159	Macaca mulatta	79.00	0.00e+00	896.00
IUUC-Mga-060135	Meleagris gallopavo	81.34	0.00e+00	903.00
IUUC-Mmr-061168	Microcebus murinus	79.18	0.00e+00	898.00
IUUC-Mdo-063030	Monodelphis domestica	79.54	0.00e+00	902.00
IUUC-Mmu-063893	Mus musculus	80.76	0.00e+00	904.00
IUUC-Mpu-066411	Mustela putorius furo	81.65	0.00e+00	912.00
IUUC-Mlu-068139	Myotis lucifugus	80.43	0.00e+00	897.00
IUUC-Nle-070178	Nomascus leucogenys	78.26	0.00e+00	862.00
IUUC-Ont-072130	Oreochromis niloticus	95.64	0.00e+00	1070.00
IUUC-Ocu-074403	Oryctolagus cuniculus	80.43	0.00e+00	899.00
IUUC-Ola-086527	Oryzias latipes	93.82	0.00e+00	1046.00
IUUC-Oga-088493	Otolemur garnettii	80.76	0.00e+00	902.00
IUUC-Oar-090279	Ovis aries	82.20	0.00e+00	914.00
IUUC-Ptr-091050	Pan troglodytes	80.98	0.00e+00	901.00
IUUC-Pan-091862	Papio anubis	81.47	0.00e+00	907.00
IUUC-Psi-093071	Pelodiscus sinensis	81.28	0.00e+00	908.00
IUUC-Pfo-096578	Poecilia formosa	94.91	0.00e+00	1083.00
IUUC-Pab-097902	Pongo abelii	79.57	0.00e+00	898.00
IUUC-Rno-105847	Rattus norvegicus	80.58	0.00e+00	902.00
IUUC-Sha-107539	Sarcophilus harrisii	81.47	0.00e+00	910.00
IUUC-Stu-112331	Solanum tuberosum	32.40	1.00e-21	98.60
IUUC-Ssc-115762	Sus scrofa	80.98	0.00e+00	900.00
IUUC-Tru-117854	Takifugu rubripes	95.82	0.00e+00	1038.00
IUUC-Ttr-128702	Tursiops truncatus	76.23	0.00e+00	831.00
IUUC-Vvi-131181	Vitis vinifera	32.06	2.00e-20	94.40
IUUC-Xtr-132291	Xenopus tropicalis	80.99	0.00e+00	868.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence