iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089277

Ensembl Protein ID

ENSOARP00000014791.1

UniProt Accession

W5PWF8; W5PWF8_SHEEP

Genbank Protein ID

ENSOARP00000014791

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01059082

Gene Name

TRIM39

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013795.1	ENSOART00000015011.1	ENSOARP00000014791.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.80e-08	32.5	27	87
E3 activity/RING/RING	3.10e-08	34.2	29	70

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPnltlrrl 64
             C++ le  ++Pv++++G+ + +++I +w ++ ++   cPv+r++ + ++l Pn  l ++
   Q: 27   ASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERdfPCPVCRKTSRYRSLRPNRQLGSM 87
           68*****************************88887799****************998666 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle +k+ p++  CgH f++ C+ +w        + f CP+Cr
   Q: 29   CSVCLEYLKE-PVIIECGHNFCKACITRW---WEDLERDFPCPVCR 70
           ********99.999************999...666889999****8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAETSLLEAG ASAASTAAAL ENLQVEASCS VCLEYLKEPV IIECGHNFCK ACITRWWEDL 60
ERDFPCPVCR KTSRYRSLRP NRQLGSMVEI AKQLQAVKRK IRDESLCPQH HEALSLFCYE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGA CAAGTCTTTT AGAGGCCGGG GCCTCTGCAG CCTCCACAGC TGCAGCTCTG 60
GAGAACCTAC AGGTGGAGGC AAGTTGCTCT GTGTGCCTGG AGTATCTGAA GGAGCCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0008270--F:zinc ion binding
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001603	Ailuropoda melanoleuca	93.85	0.00e+00	905.00
IUUC-Apl-003354	Anas platyrhynchos	43.08	2.00e-106	379.00
IUUC-Aca-005381	Anolis carolinensis	66.80	0.00e+00	632.00
IUUC-Ame-011639	Astyanax mexicanus	33.47	2.00e-70	259.00
IUUC-Bta-012554	Bos taurus	89.72	2.00e-143	501.00
IUUC-Cja-019323	Callithrix jacchus	94.00	0.00e+00	902.00
IUUC-Cfa-020342	Canis familiaris	93.79	0.00e+00	901.00
IUUC-Cpo-022084	Cavia porcellus	88.65	3.00e-141	494.00
IUUC-Csa-023186	Chlorocebus sabaeus	94.00	0.00e+00	903.00
IUUC-Cho-024697	Choloepus hoffmanni	87.04	0.00e+00	857.00
IUUC-Dre-028792	Danio rerio	34.85	4.00e-71	262.00
IUUC-Dno-028914	Dasypus novemcinctus	44.75	6.00e-110	390.00
IUUC-Dor-031021	Dipodomys ordii	79.49	2.00e-128	452.00
IUUC-Ete-032936	Echinops telfairi	86.89	5.00e-153	533.00
IUUC-Eca-033687	Equus caballus	89.36	6.00e-143	500.00
IUUC-Eeu-034957	Erinaceus europaeus	99.55	8.00e-132	463.00
IUUC-Fca-035406	Felis catus	93.58	0.00e+00	900.00
IUUC-Fal-036705	Ficedula albicollis	44.52	2.00e-97	349.00
IUUC-Gmo-038505	Gadus morhua	34.13	3.00e-68	252.00
IUUC-Gga-040491	Gallus gallus	43.01	5.00e-101	361.00
IUUC-Gac-041919	Gasterosteus aculeatus	35.33	6.00e-70	258.00
IUUC-Ggo-044526	Gorilla gorilla	88.33	0.00e+00	887.00
IUUC-Hsa-045719	Homo sapiens	88.33	0.00e+00	888.00
IUUC-Itr-048404	Ictidomys tridecemlineatus	92.21	0.00e+00	891.00
IUUC-Lch-049787	Latimeria chalumnae	39.78	3.00e-86	311.00
IUUC-Laf-054295	Loxodonta africana	92.96	0.00e+00	897.00
IUUC-Mcc-055765	Macaca mulatta	89.59	0.00e+00	890.00
IUUC-Meu-055997	Macropus eugenii	57.70	8.00e-124	436.00
IUUC-Mmr-061030	Microcebus murinus	90.54	0.00e+00	639.00
IUUC-Mdo-062936	Monodelphis domestica	84.69	0.00e+00	799.00
IUUC-Mmu-063767	Mus musculus	92.51	0.00e+00	889.00
IUUC-Mpu-066160	Mustela putorius furo	93.85	0.00e+00	904.00
IUUC-Mlu-068126	Myotis lucifugus	86.52	3.00e-139	488.00
IUUC-Nle-070041	Nomascus leucogenys	83.51	0.00e+00	759.00
IUUC-Opr-070394	Ochotona princeps	88.06	0.00e+00	883.00
IUUC-Oan-072828	Ornithorhynchus anatinus	56.26	3.00e-155	541.00
IUUC-Ocu-073980	Oryctolagus cuniculus	89.97	0.00e+00	635.00
IUUC-Oga-088422	Otolemur garnettii	88.41	0.00e+00	865.00
IUUC-Ptr-090853	Pan troglodytes	88.33	0.00e+00	887.00
IUUC-Pan-091993	Papio anubis	94.00	0.00e+00	903.00
IUUC-Psi-092975	Pelodiscus sinensis	72.02	3.00e-177	614.00
IUUC-Pfo-096831	Poecilia formosa	31.73	4.00e-65	242.00
IUUC-Pab-097944	Pongo abelii	94.00	0.00e+00	903.00
IUUC-Pca-100795	Procavia capensis	87.24	1.00e-161	563.00
IUUC-Pva-103180	Pteropus vampyrus	87.17	0.00e+00	869.00
IUUC-Rno-105736	Rattus norvegicus	90.95	0.00e+00	879.00
IUUC-Sha-107411	Sarcophilus harrisii	51.80	4.00e-142	497.00
IUUC-Sar-113371	Sorex araneus	84.22	0.00e+00	697.00
IUUC-Ssc-116025	Sus scrofa	94.22	0.00e+00	904.00
IUUC-Tgu-116998	Taeniopygia guttata	45.55	2.00e-101	362.00
IUUC-Tsy-119072	Tarsius syrichta	90.77	3.00e-177	613.00
IUUC-Tbe-127820	Tupaia belangeri	79.37	1.00e-122	433.00
IUUC-Ttr-128310	Tursiops truncatus	99.10	3.00e-132	465.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence