iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074912

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02025341

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000000005.3	ENSOCUT00000000005.3	ENSOCUP00000000005.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.82	0.00e+00	816.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTSLSTSAQC SASESACGIS TERINQVRPK LPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVSLA TATTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTACACAC AGGCTGCGAT TTCTTCACTG CCAAAATGAC ATCACTTTCT ACTTCTGCCC 60
AGTGTTCAGC ATCCGAGAGT GCTTGCGGGA TCTCTACAGA ACGAATCAAT CAGGTAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

KEGG

ocu:100351683

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	89.84	0.00e+00	782.00
IUUC-Apl-003800	Anas platyrhynchos	58.91	2.00e-151	529.00
IUUC-Aca-004608	Anolis carolinensis	55.51	7.00e-137	480.00
IUUC-Ame-010869	Astyanax mexicanus	47.11	1.00e-104	373.00
IUUC-Bta-013287	Bos taurus	87.17	0.00e+00	833.00
IUUC-Cja-019305	Callithrix jacchus	89.21	0.00e+00	797.00
IUUC-Cfa-020393	Canis familiaris	90.45	0.00e+00	803.00
IUUC-Cpo-022166	Cavia porcellus	90.34	0.00e+00	765.00
IUUC-Csa-023654	Chlorocebus sabaeus	90.22	0.00e+00	784.00
IUUC-Cho-024403	Choloepus hoffmanni	86.89	2.00e-124	439.00
IUUC-Cin-025448	Ciona intestinalis	27.27	4.00e-20	91.30
IUUC-Dre-027754	Danio rerio	49.41	1.00e-114	406.00
IUUC-Dno-029630	Dasypus novemcinctus	87.60	0.00e+00	802.00
IUUC-Dor-031064	Dipodomys ordii	68.64	0.00e+00	639.00
IUUC-Ete-032901	Echinops telfairi	78.25	0.00e+00	754.00
IUUC-Eca-034234	Equus caballus	91.65	0.00e+00	879.00
IUUC-Eeu-035015	Erinaceus europaeus	64.84	4.00e-160	557.00
IUUC-Fca-036587	Felis catus	90.84	0.00e+00	824.00
IUUC-Fal-036906	Ficedula albicollis	50.31	4.00e-131	461.00
IUUC-Gmo-038646	Gadus morhua	43.67	1.00e-93	336.00
IUUC-Gga-040124	Gallus gallus	57.02	6.00e-113	400.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.29	2.00e-103	369.00
IUUC-Ggo-045505	Gorilla gorilla	89.82	0.00e+00	797.00
IUUC-Hsa-046950	Homo sapiens	89.82	0.00e+00	798.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	88.59	0.00e+00	809.00
IUUC-Lch-050141	Latimeria chalumnae	53.86	4.00e-123	434.00
IUUC-Loc-051921	Lepisosteus oculatus	50.49	4.00e-111	394.00
IUUC-Laf-054281	Loxodonta africana	86.35	0.00e+00	780.00
IUUC-Mcc-055462	Macaca mulatta	86.18	0.00e+00	731.00
IUUC-Meu-056294	Macropus eugenii	70.67	3.00e-141	494.00
IUUC-Mga-059924	Meleagris gallopavo	58.62	8.00e-160	556.00
IUUC-Mmr-061428	Microcebus murinus	89.41	0.00e+00	845.00
IUUC-Mdo-062643	Monodelphis domestica	76.26	0.00e+00	729.00
IUUC-Mmu-063229	Mus musculus	81.87	0.00e+00	754.00
IUUC-Mpu-065782	Mustela putorius furo	87.63	0.00e+00	785.00
IUUC-Mlu-068105	Myotis lucifugus	78.86	0.00e+00	747.00
IUUC-Nle-069549	Nomascus leucogenys	90.22	0.00e+00	802.00
IUUC-Opr-070568	Ochotona princeps	92.47	0.00e+00	816.00
IUUC-Ont-072276	Oreochromis niloticus	47.29	1.00e-112	400.00
IUUC-Oan-072787	Ornithorhynchus anatinus	72.81	0.00e+00	655.00
IUUC-Ola-087037	Oryzias latipes	45.51	8.00e-98	350.00
IUUC-Oga-088953	Otolemur garnettii	86.06	0.00e+00	792.00
IUUC-Oar-089202	Ovis aries	87.17	0.00e+00	837.00
IUUC-Ptr-090964	Pan troglodytes	90.22	0.00e+00	802.00
IUUC-Pan-091975	Papio anubis	90.22	0.00e+00	803.00
IUUC-Psi-093558	Pelodiscus sinensis	59.67	1.00e-156	546.00
IUUC-Pfo-096454	Poecilia formosa	47.46	2.00e-109	389.00
IUUC-Pab-098123	Pongo abelii	90.02	0.00e+00	803.00
IUUC-Pca-101112	Procavia capensis	76.83	0.00e+00	704.00
IUUC-Pva-103098	Pteropus vampyrus	79.63	0.00e+00	745.00
IUUC-Rno-105930	Rattus norvegicus	82.93	0.00e+00	739.00
IUUC-Sha-107512	Sarcophilus harrisii	74.59	0.00e+00	649.00
IUUC-Sar-113584	Sorex araneus	80.24	0.00e+00	700.00
IUUC-Tgu-116766	Taeniopygia guttata	54.52	1.00e-98	352.00
IUUC-Tru-117829	Takifugu rubripes	47.58	2.00e-110	392.00
IUUC-Tsy-119268	Tarsius syrichta	75.97	0.00e+00	663.00
IUUC-Tni-120204	Tetraodon nigroviridis	47.42	1.00e-106	379.00
IUUC-Tbe-127840	Tupaia belangeri	82.52	3.00e-120	424.00
IUUC-Ttr-128863	Tursiops truncatus	87.17	0.00e+00	810.00
IUUC-Vpa-130718	Vicugna pacos	90.32	0.00e+00	788.00
IUUC-Xtr-132320	Xenopus tropicalis	45.93	4.00e-88	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence