iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000012493.2	ENSSTOT00000029733.1	ENSSTOP00000015725.1
ENSSTOG00000012493.2	ENSSTOT00000012490.2	ENSSTOP00000011194.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.30e-16	58.5	163	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ +SLqhLCRl+I++c+g+     +++LPLP +LkdYL+++++q
   Q: 163  TKPLYTSAPSLQHLCRLTINKCTGT-----VWGLPLPTRLKDYLEEYKFQ 207
           678999*******************.....8***************9886 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTLRCLEPSI GQGRGTEGKI PSLGVPVFPY GSWAFPWPER PADYKARKIT GKTKTPGWYW 60
GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GCCCTCNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	81.73	4.00e-89	320.00
IUUC-Apl-003484	Anas platyrhynchos	79.61	7.00e-72	261.00
IUUC-Aca-004253	Anolis carolinensis	70.97	4.00e-68	249.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	3.20e-02	32.30
IUUC-Ame-011267	Astyanax mexicanus	64.78	8.00e-57	212.00
IUUC-Bta-013183	Bos taurus	78.85	5.00e-88	316.00
IUUC-Bra-017915	Brassica rapa	33.90	5.90e-02	31.60
IUUC-Cja-018862	Callithrix jacchus	82.21	2.00e-89	321.00
IUUC-Cfa-020226	Canis familiaris	79.71	7.00e-87	312.00
IUUC-Cpo-022414	Cavia porcellus	82.21	5.00e-91	326.00
IUUC-Csa-023758	Chlorocebus sabaeus	82.21	4.00e-91	326.00
IUUC-Cho-024471	Choloepus hoffmanni	86.18	2.00e-71	261.00
IUUC-Dre-028288	Danio rerio	64.56	2.00e-58	218.00
IUUC-Dno-029565	Dasypus novemcinctus	83.65	9.00e-94	335.00
IUUC-Dor-030447	Dipodomys ordii	98.01	1.00e-86	311.00
IUUC-Ete-033023	Echinops telfairi	80.29	2.00e-90	324.00
IUUC-Fca-036469	Felis catus	82.21	5.00e-89	319.00
IUUC-Fal-036642	Ficedula albicollis	77.56	1.00e-70	258.00
IUUC-Gmo-039331	Gadus morhua	68.67	1.00e-31	127.00
IUUC-Gga-040809	Gallus gallus	77.42	1.00e-71	261.00
IUUC-Gac-041398	Gasterosteus aculeatus	61.54	1.00e-54	205.00
IUUC-Ggo-045341	Gorilla gorilla	82.69	1.00e-89	321.00
IUUC-Hsa-046557	Homo sapiens	82.21	4.00e-93	333.00
IUUC-Lch-050160	Latimeria chalumnae	62.86	7.00e-47	179.00
IUUC-Loc-051825	Lepisosteus oculatus	64.74	8.00e-57	212.00
IUUC-Laf-053560	Loxodonta africana	77.88	1.00e-87	315.00
IUUC-Mcc-055890	Macaca mulatta	77.88	1.00e-88	318.00
IUUC-Meu-056218	Macropus eugenii	66.83	2.00e-79	287.00
IUUC-Mga-059755	Meleagris gallopavo	79.08	1.00e-71	261.00
IUUC-Mmr-061387	Microcebus murinus	81.73	4.00e-90	323.00
IUUC-Mdo-062383	Monodelphis domestica	68.90	1.00e-80	291.00
IUUC-Mmu-063443	Mus musculus	76.92	5.00e-89	319.00
IUUC-Mpu-066459	Mustela putorius furo	76.92	1.00e-87	315.00
IUUC-Mlu-068040	Myotis lucifugus	81.25	4.00e-89	319.00
IUUC-Nle-069016	Nomascus leucogenys	81.25	4.00e-93	333.00
IUUC-Opr-071087	Ochotona princeps	76.30	1.00e-86	311.00
IUUC-Ont-072340	Oreochromis niloticus	61.73	1.00e-55	208.00
IUUC-Oan-073443	Ornithorhynchus anatinus	72.12	2.00e-81	294.00
IUUC-Ocu-074539	Oryctolagus cuniculus	78.74	3.00e-87	313.00
IUUC-Ogu-078951	Oryza glumaepatula	27.03	8.10e-02	31.60
IUUC-Oin-079476	Oryza indica	27.03	7.20e-02	31.60
IUUC-Oni-082613	Oryza nivara	27.03	7.20e-02	31.60
IUUC-Oru-085265	Oryza rufipogon	27.03	7.60e-02	31.60
IUUC-Ola-087004	Oryzias latipes	60.13	4.00e-55	206.00
IUUC-Oga-088438	Otolemur garnettii	81.73	5.00e-91	326.00
IUUC-Oar-089932	Ovis aries	77.88	2.00e-87	314.00
IUUC-Ptr-091037	Pan troglodytes	82.69	1.00e-89	321.00
IUUC-Pan-092767	Papio anubis	78.37	2.00e-89	321.00
IUUC-Psi-093099	Pelodiscus sinensis	76.77	9.00e-72	261.00
IUUC-Pma-094671	Petromyzon marinus	48.05	5.00e-36	144.00
IUUC-Pfo-097073	Poecilia formosa	57.14	7.00e-51	193.00
IUUC-Pab-098319	Pongo abelii	80.77	1.00e-90	325.00
IUUC-Pca-101117	Procavia capensis	77.88	9.00e-88	315.00
IUUC-Pva-102117	Pteropus vampyrus	77.88	5.00e-88	316.00
IUUC-Rno-105913	Rattus norvegicus	76.44	4.00e-88	317.00
IUUC-Sha-106500	Sarcophilus harrisii	70.33	3.00e-82	296.00
IUUC-Ssc-115252	Sus scrofa	82.21	1.00e-90	325.00
IUUC-Tgu-117524	Taeniopygia guttata	76.13	6.00e-69	252.00
IUUC-Tsy-119335	Tarsius syrichta	94.70	6.00e-84	301.00
IUUC-Tni-120263	Tetraodon nigroviridis	58.18	2.00e-53	201.00
IUUC-Tbe-127915	Tupaia belangeri	77.88	8.00e-86	308.00
IUUC-Ttr-128372	Tursiops truncatus	82.21	1.00e-90	324.00
IUUC-Vpa-130422	Vicugna pacos	98.01	2.00e-86	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence