iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062144

Ensembl Protein ID

ENSMODP00000005181.3

UniProt Accession

K7E1D9; K7E1D9_MONDO

Protein Name

Inhibitor of growth protein

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004200.3	ENSMODT00000042696.1	ENSMODP00000039590.1
ENSMODG00000004200.3	ENSMODT00000005291.2	ENSMODP00000005181.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.60e-09	37.3	234	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 234  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 280
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

GGRGGACVTA GCGGGGGGGG RLGQQQQQQL YPAAGLLAGE RGRLLSCYVQ DYLECVESLP 60
LDMQRNVSVL REIDTKYQEA LKEIDDACEK YKKENDPHQK KRLQQNLQRA LINSQELGDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGCCGTG GCGGTGCATG TGTGACCGCT GGATGCGGAG GAGGCGGCGG CGGCGGCGGC 60
AGCAACAGCA GCAGCAGCAG AAGCAGAAGC AGCAAAATGT TAGGACAGCA ACAGCAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

KEGG

mdo:100012534

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	91.18	2.00e-110	391.00
IUUC-Apl-003705	Anas platyrhynchos	90.13	6.00e-92	329.00
IUUC-Aca-004990	Anolis carolinensis	82.63	1.00e-98	352.00
IUUC-Ame-011426	Astyanax mexicanus	71.27	8.00e-85	306.00
IUUC-Bta-012721	Bos taurus	91.54	3.00e-111	394.00
IUUC-Cja-018960	Callithrix jacchus	92.80	1.00e-99	355.00
IUUC-Cfa-020869	Canis familiaris	91.18	5.00e-110	390.00
IUUC-Cpo-021414	Cavia porcellus	89.71	8.00e-109	386.00
IUUC-Csa-023304	Chlorocebus sabaeus	92.65	5.00e-104	370.00
IUUC-Dre-028562	Danio rerio	73.26	5.00e-88	317.00
IUUC-Dno-029945	Dasypus novemcinctus	92.05	1.00e-107	382.00
IUUC-Dor-030141	Dipodomys ordii	91.54	3.00e-110	391.00
IUUC-Ete-032709	Echinops telfairi	90.81	2.00e-118	418.00
IUUC-Eca-033432	Equus caballus	92.28	4.00e-111	394.00
IUUC-Eeu-035285	Erinaceus europaeus	95.59	1.00e-86	312.00
IUUC-Fca-036467	Felis catus	92.42	2.00e-107	381.00
IUUC-Fal-036700	Ficedula albicollis	88.89	2.00e-91	328.00
IUUC-Gmo-038748	Gadus morhua	62.90	3.00e-84	304.00
IUUC-Gga-040175	Gallus gallus	89.69	8.00e-92	329.00
IUUC-Gac-041403	Gasterosteus aculeatus	64.06	8.00e-89	319.00
IUUC-Hsa-045837	Homo sapiens	92.65	5.00e-104	370.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	91.18	3.00e-110	390.00
IUUC-Lch-049965	Latimeria chalumnae	82.06	6.00e-101	360.00
IUUC-Laf-053353	Loxodonta africana	92.89	2.00e-94	338.00
IUUC-Mcc-055155	Macaca mulatta	97.70	1.00e-71	261.00
IUUC-Meu-056470	Macropus eugenii	99.61	2.00e-120	424.00
IUUC-Mga-059570	Meleagris gallopavo	89.69	4.00e-91	327.00
IUUC-Mmr-061385	Microcebus murinus	92.28	1.00e-103	369.00
IUUC-Mmu-063215	Mus musculus	91.18	4.00e-111	394.00
IUUC-Mpu-065749	Mustela putorius furo	92.47	1.00e-93	335.00
IUUC-Nle-069968	Nomascus leucogenys	97.37	3.00e-80	291.00
IUUC-Ont-071524	Oreochromis niloticus	66.91	6.00e-86	310.00
IUUC-Ocu-074870	Oryctolagus cuniculus	91.91	2.00e-111	394.00
IUUC-Oga-088336	Otolemur garnettii	91.91	5.00e-103	367.00
IUUC-Oar-090136	Ovis aries	91.45	2.00e-109	388.00
IUUC-Ptr-091348	Pan troglodytes	97.89	6.00e-81	293.00
IUUC-Pan-092819	Papio anubis	92.65	5.00e-104	370.00
IUUC-Pfo-096633	Poecilia formosa	67.64	7.00e-80	290.00
IUUC-Pab-098346	Pongo abelii	92.28	1.00e-103	369.00
IUUC-Pca-100278	Procavia capensis	90.94	9.00e-109	385.00
IUUC-Pva-103190	Pteropus vampyrus	93.18	1.00e-108	385.00
IUUC-Rno-104940	Rattus norvegicus	91.29	1.00e-106	379.00
IUUC-Sha-107533	Sarcophilus harrisii	99.26	8.00e-123	432.00
IUUC-Sar-113630	Sorex araneus	94.12	5.00e-86	310.00
IUUC-Ssc-115734	Sus scrofa	93.18	3.00e-108	384.00
IUUC-Tgu-117034	Taeniopygia guttata	89.33	9.00e-92	329.00
IUUC-Tru-118168	Takifugu rubripes	61.57	2.00e-80	292.00
IUUC-Tsy-119494	Tarsius syrichta	97.37	2.00e-80	291.00
IUUC-Tni-120100	Tetraodon nigroviridis	62.21	2.00e-76	278.00
IUUC-Ttr-128442	Tursiops truncatus	96.08	5.00e-87	313.00
IUUC-Vpa-130063	Vicugna pacos	91.54	1.00e-110	392.00
IUUC-Xtr-132348	Xenopus tropicalis	70.96	2.00e-65	242.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence