iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074870

Ensembl Protein ID

ENSOCUP00000010152.3

UniProt Accession

G1T213; G1T213_RABIT

Genbank Protein ID

ENSOCUP00000010152

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAGW02011538

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011812.3	ENSOCUT00000011809.3	ENSOCUP00000010152.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.90e-09	36.6	216	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 216  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 262
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLGQQQQQQQ QLYSSAALLT GERSRLLTCY VQDYLECVES LPHDMQRNVS VLRELDNKYQ 60
ETLKEIDDVY EKYKKEDDSN QKKRLQQHLQ RALINSQELG DEKIQIVTQM LELVENRARQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTAGGGC AGCAGCAGCA GCAGCAGCAG CAACTGTACT CGTCGGCCGC GCTCCTGACC 60
GGGGAGCGGA GCCGGCTGCT CACCTGCTAC GTGCAGGACT ACCTCGAGTG TGTGGAGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

KEGG

ocu:100341244

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	98.90	9.00e-121	426.00
IUUC-Apl-003705	Anas platyrhynchos	89.24	4.00e-92	330.00
IUUC-Aca-004990	Anolis carolinensis	81.08	1.00e-97	349.00
IUUC-Ame-011426	Astyanax mexicanus	70.80	4.00e-84	304.00
IUUC-Bta-012721	Bos taurus	98.94	3.00e-122	430.00
IUUC-Cja-018960	Callithrix jacchus	98.48	7.00e-107	379.00
IUUC-Cfa-020869	Canis familiaris	98.53	3.00e-120	424.00
IUUC-Cpo-021414	Cavia porcellus	96.69	2.00e-118	417.00
IUUC-Csa-023304	Chlorocebus sabaeus	98.53	2.00e-111	395.00
IUUC-Dre-028562	Danio rerio	68.63	9.00e-89	319.00
IUUC-Dno-029945	Dasypus novemcinctus	98.48	3.00e-116	410.00
IUUC-Dor-030141	Dipodomys ordii	97.06	2.00e-117	414.00
IUUC-Ete-032709	Echinops telfairi	96.82	3.00e-129	454.00
IUUC-Eca-033432	Equus caballus	99.26	8.00e-121	426.00
IUUC-Eeu-035285	Erinaceus europaeus	99.51	4.00e-92	330.00
IUUC-Fca-036467	Felis catus	99.24	2.00e-116	411.00
IUUC-Fal-036700	Ficedula albicollis	88.00	2.00e-91	327.00
IUUC-Gmo-038748	Gadus morhua	62.68	3.00e-85	307.00
IUUC-Gga-040175	Gallus gallus	88.79	5.00e-92	330.00
IUUC-Gac-041403	Gasterosteus aculeatus	64.47	1.00e-89	322.00
IUUC-Hsa-045837	Homo sapiens	98.53	2.00e-111	395.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	99.26	2.00e-121	427.00
IUUC-Lch-049965	Latimeria chalumnae	81.30	6.00e-101	359.00
IUUC-Laf-053353	Loxodonta africana	96.89	1.00e-100	358.00
IUUC-Mcc-055155	Macaca mulatta	98.85	3.00e-73	267.00
IUUC-Meu-056470	Macropus eugenii	93.31	3.00e-111	394.00
IUUC-Mga-059570	Meleagris gallopavo	88.79	2.00e-91	327.00
IUUC-Mmr-061385	Microcebus murinus	98.90	5.00e-112	396.00
IUUC-Mdo-062144	Monodelphis domestica	93.36	1.00e-112	399.00
IUUC-Mmu-063215	Mus musculus	97.43	8.00e-120	422.00
IUUC-Mpu-065749	Mustela putorius furo	98.33	4.00e-100	357.00
IUUC-Nle-069968	Nomascus leucogenys	98.42	6.00e-82	296.00
IUUC-Ont-071524	Oreochromis niloticus	65.93	1.00e-86	312.00
IUUC-Oga-088336	Otolemur garnettii	98.59	1.00e-112	399.00
IUUC-Oar-090136	Ovis aries	97.88	5.00e-120	423.00
IUUC-Ptr-091348	Pan troglodytes	98.95	1.00e-82	298.00
IUUC-Pan-092819	Papio anubis	98.53	2.00e-111	395.00
IUUC-Pfo-096633	Poecilia formosa	66.30	2.00e-80	291.00
IUUC-Pab-098346	Pongo abelii	98.90	4.00e-112	397.00
IUUC-Pca-100278	Procavia capensis	96.46	1.00e-117	415.00
IUUC-Pva-103190	Pteropus vampyrus	99.62	4.00e-117	413.00
IUUC-Rno-104940	Rattus norvegicus	97.35	1.00e-114	405.00
IUUC-Sha-107533	Sarcophilus harrisii	91.54	1.00e-113	402.00
IUUC-Sar-113630	Sorex araneus	97.07	9.00e-91	325.00
IUUC-Ssc-115734	Sus scrofa	99.62	4.00e-117	413.00
IUUC-Tgu-117034	Taeniopygia guttata	88.44	5.00e-92	330.00
IUUC-Tru-118168	Takifugu rubripes	61.68	4.00e-81	294.00
IUUC-Tsy-119494	Tarsius syrichta	99.47	3.00e-83	300.00
IUUC-Tni-120100	Tetraodon nigroviridis	62.20	4.00e-77	280.00
IUUC-Ttr-128442	Tursiops truncatus	99.02	1.00e-91	328.00
IUUC-Vpa-130063	Vicugna pacos	98.53	2.00e-120	424.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence