iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050237

Ensembl Protein ID

ENSLACP00000012195.1

UniProt Accession

H3ARC4; H3ARC4_LATCH

Genbank Protein ID

ENSLACP00000012195

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01060498

Gene Name

usp12b; LOC102363119

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010732.1	ENSLACT00000012287.1	ENSLACP00000012195.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-97	326.6	39	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l     k++    + +k++ll++l +lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA---YKVQ----PRKKENLLTCLSDLFNSIAtqKKKVGVIPPKKFISRLRKENELFDNY 120
           6******************************...5554....457899************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l    +++k++e+++ k +  + ++e+ +k + ++++d+Fqg+l+++++cl+c++vss++e+fldls++v
   Q: 121  MQQDAHEFLNYLLNTIADLL----QEEKKQEKQNGKLQNGSLESEEGEKTELTWVHDIFQGTLTNETRCLNCESVSSKDEDFLDLSVDV 205
           ********************....4455566666666777778899999999************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL+ f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++  + ++ +k++ +v fpleL l  f+
   Q: 206  EQNT-----SITHCLRGFSNTETLCSEQKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--FN 287
           ****.....9**********************************************************************66665..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts + + + ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 288  TSGDAT-NPERMYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 367
           774444.469***************************.888*******************999*****************97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MEILMTVRKI ASICTMGTNA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFREKVLAY KVQPRKKENL LTCLSDLFNS IATQKKKVGV IPPKKFISRL RKENELFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTGTTCCA ACATGGCGGT GGACGGATGG AAATACTGAT GACAGTCCGA AAAATCGCTT 60
CGATTTGTAC GATGGTGAGC TGCTCCTTCC CTCGTGTGCC GGGTTGCAAT GGACCGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102363119

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003733	Anas platyrhynchos	94.04	0.00e+00	687.00
IUUC-Aca-005054	Anolis carolinensis	94.89	0.00e+00	683.00
IUUC-Ame-011132	Astyanax mexicanus	90.44	0.00e+00	717.00
IUUC-Bta-012981	Bos taurus	91.06	0.00e+00	714.00
IUUC-Csv-025828	Ciona savignyi	71.90	2.00e-89	322.00
IUUC-Cne-026900	Cryptococcus neoformans	41.45	2.00e-59	223.00
IUUC-Dre-027548	Danio rerio	90.86	0.00e+00	711.00
IUUC-Fal-037172	Ficedula albicollis	94.85	0.00e+00	698.00
IUUC-Gmo-038763	Gadus morhua	87.63	0.00e+00	690.00
IUUC-Gga-041044	Gallus gallus	96.48	0.00e+00	711.00
IUUC-Gac-041967	Gasterosteus aculeatus	87.90	0.00e+00	692.00
IUUC-Loc-052559	Lepisosteus oculatus	95.93	0.00e+00	745.00
IUUC-Mga-059602	Meleagris gallopavo	96.92	0.00e+00	686.00
IUUC-Mmu-063263	Mus musculus	90.81	0.00e+00	710.00
IUUC-Ncr-068699	Neurospora crassa	43.23	4.00e-74	273.00
IUUC-Ont-072049	Oreochromis niloticus	88.78	0.00e+00	707.00
IUUC-Ola-087325	Oryzias latipes	87.80	0.00e+00	669.00
IUUC-Olu-087809	Ostreococcus lucimarinus	49.14	5.00e-82	297.00
IUUC-Psi-093379	Pelodiscus sinensis	97.02	0.00e+00	713.00
IUUC-Pma-094388	Petromyzon marinus	89.81	0.00e+00	700.00
IUUC-Sce-106196	Saccharomyces cerevisiae	37.46	2.00e-55	210.00
IUUC-Tgu-116825	Taeniopygia guttata	95.66	0.00e+00	705.00
IUUC-Tru-118379	Takifugu rubripes	93.05	0.00e+00	715.00
IUUC-Tvi-122330	Trichoderma virens	45.03	2.00e-74	273.00
IUUC-Vda-129736	Verticillium dahliae	38.44	8.00e-58	218.00
IUUC-Xtr-132082	Xenopus tropicalis	95.39	0.00e+00	743.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence