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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105255
Ensembl Protein ID ENSRNOP00000062066.2
UniProt Accession Q5I0D6; Q923J7; NOSTN_RAT
Genbank Protein ID AAH88446.1; AAK64518.1
Protein Name Nostrin; BM247; Nitric oxide synthase trafficker; eNOS-trafficking inducer
Genbank Nucleotide ID BC088446; AY032855
Gene Name Nostrin
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000006611.7 ENSRNOT00000067161.3 ENSRNOP00000062066.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.20e-17 64.0 439 495
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +++++++ly ++a +ddeL+l+kGd+v++  +e+++egW+ g   l+gk+G fP+ +ve+l
   Q: 439  NNQLCKALYTFQARQDDELNLEKGDIVTI--HEKKEEGWWFG--SLNGKKGHFPAAYVEEL 495
           5789*************************..59*********..9**************98 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
 Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Protein Sequence
(Fasta)
MRDPLTDCSY NKVYKSLKEF AQNGDNFCKQ ITSVLQQRAN LEISYAKGLQ KLAVKLSKAL 60
QSTKKNCLST AWAWASESMK SAADLHQKLG KAIELEAIKP THQVLSMQEK KRKSLDNEVE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105255|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACTGACGTAC TCTAAGCCCT TTGAATCCCG GAAGTCCAGA ACACACCCAA CCTAATTGAT 60
TGCAGCGTCC AGCATGCTGG AGCGTAGGTA AAAGAAAAAG CAGACAACAT TTCAACATGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105255|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR011072--HR1_rho-bd
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
PROSITE

PS51741--F_BAR
PS50002--SH3
Pfam

PF00611--FCH
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA
SMART

SM00055--FCH
SM00326--SH3
Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005856--C:cytoskeleton
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0003677--F:DNA binding
GO:0006897--P:endocytosis
GO:0045892--P:negative regulation of transcription, DNA-templated
KEGG rno:311111
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001403 Ailuropoda melanoleuca 73.91 1.00e-106 380.00
IUUC-Aca-005138 Anolis carolinensis 49.61 6.00e-132 464.00
IUUC-Bta-012680 Bos taurus 79.40 0.00e+00 743.00
IUUC-Cja-019985 Callithrix jacchus 82.40 0.00e+00 786.00
IUUC-Cfa-020888 Canis familiaris 73.19 3.00e-106 379.00
IUUC-Cpo-021852 Cavia porcellus 81.87 0.00e+00 733.00
IUUC-Csa-023196 Chlorocebus sabaeus 82.60 0.00e+00 763.00
IUUC-Cin-025272 Ciona intestinalis 26.32 1.00e-33 137.00
IUUC-Dre-027969 Danio rerio 44.13 4.00e-114 404.00
IUUC-Dno-029703 Dasypus novemcinctus 79.19 0.00e+00 710.00
IUUC-Dor-030928 Dipodomys ordii 82.20 0.00e+00 751.00
IUUC-Dme-032164 Drosophila melanogaster 25.06 1.00e-20 95.90
IUUC-Ete-033034 Echinops telfairi 63.53 8.00e-146 510.00
IUUC-Eca-034165 Equus caballus 79.48 0.00e+00 769.00
IUUC-Eeu-034697 Erinaceus europaeus 77.89 0.00e+00 762.00
IUUC-Fca-035811 Felis catus 76.46 0.00e+00 708.00
IUUC-Gac-041751 Gasterosteus aculeatus 44.35 2.00e-115 409.00
IUUC-Hsa-046868 Homo sapiens 72.17 0.00e+00 691.00
IUUC-Itr-049056 Ictidomys tridecemlineatus 84.40 0.00e+00 806.00
IUUC-Lch-050314 Latimeria chalumnae 51.55 1.00e-76 281.00
IUUC-Loc-051803 Lepisosteus oculatus 47.41 8.00e-123 434.00
IUUC-Laf-053672 Loxodonta africana 81.31 0.00e+00 764.00
IUUC-Mcc-054984 Macaca mulatta 74.73 0.00e+00 730.00
IUUC-Mmr-061250 Microcebus murinus 82.04 0.00e+00 789.00
IUUC-Mdo-062278 Monodelphis domestica 72.51 0.00e+00 684.00
IUUC-Mmu-063360 Mus musculus 94.40 0.00e+00 823.00
IUUC-Mpu-065954 Mustela putorius furo 77.82 0.00e+00 703.00
IUUC-Mlu-066993 Myotis lucifugus 76.77 0.00e+00 708.00
IUUC-Nle-069744 Nomascus leucogenys 66.73 6.00e-180 624.00
IUUC-Opr-070442 Ochotona princeps 68.74 0.00e+00 630.00
IUUC-Ont-072001 Oreochromis niloticus 42.49 3.00e-119 422.00
IUUC-Oan-072971 Ornithorhynchus anatinus 68.08 1.00e-171 596.00
IUUC-Ocu-074140 Oryctolagus cuniculus 82.40 0.00e+00 769.00
IUUC-Oba-075752 Oryza barthii 40.98 4.00e-04 41.60
IUUC-Ola-086827 Oryzias latipes 44.71 1.00e-113 403.00
IUUC-Oga-088144 Otolemur garnettii 81.00 0.00e+00 749.00
IUUC-Oar-090280 Ovis aries 79.40 0.00e+00 721.00
IUUC-Ptr-091508 Pan troglodytes 82.40 0.00e+00 748.00
IUUC-Pan-092649 Papio anubis 81.52 0.00e+00 726.00
IUUC-Pfo-097405 Poecilia formosa 43.65 6.00e-109 388.00
IUUC-Pab-097751 Pongo abelii 82.60 0.00e+00 749.00
IUUC-Pca-100878 Procavia capensis 79.24 0.00e+00 746.00
IUUC-Pva-102337 Pteropus vampyrus 77.40 0.00e+00 743.00
IUUC-Sha-106635 Sarcophilus harrisii 61.89 2.00e-151 529.00
IUUC-Ssc-116156 Sus scrofa 77.15 0.00e+00 745.00
IUUC-Tru-118662 Takifugu rubripes 44.06 7.00e-122 430.00
IUUC-Tsy-119337 Tarsius syrichta 78.57 0.00e+00 672.00
IUUC-Tbe-127388 Tupaia belangeri 84.06 0.00e+00 797.00
IUUC-Ttr-128767 Tursiops truncatus 79.40 0.00e+00 714.00
IUUC-Xtr-132443 Xenopus tropicalis 56.50 2.00e-141 496.00
Created Date 25-Jun-2017

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