iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004320

UUCD1 version

UUC-AnC-00025

Ensembl Protein ID

ENSACAP00000003858.3

UniProt Accession

H9G8B0; H9G8B0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003955.3	ENSACAT00000003950.3	ENSACAP00000003858.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.20e-18	65.4	35	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.10e-12	45.5	134	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l vg+++++ahk+vLa+ S++F+a+f+++l+e++ + +ve++ v   +++a++++ Ytg++
   Q: 35   CDVVLRVGDVKIHAHKVVLASISPYFKAMFSGNLSEKE-NAEVEFQCVAEAALQAIVEYAYTGTV 98
           9***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa ++i++hF+
   Q: 134  PGNCIGISRFAETYGCHDLYLAASKYICRHFE 165
           56*****************************5 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDRSSPTYMV ANLTPLHSEQ LLQGLNLLRQ HHELCDVVLR VGDVKIHAHK VVLASISPYF 60
KAMFSGNLSE KENAEVEFQC VAEAALQAIV EYAYTGTVFI SQDTVESLLP AANLLQIKLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCGGT CGTCCCCAAC CTACATGGTT GCCAACTTGA CCCCTCTGCA CTCTGAGCAG 60
CTCCTGCAGG GCCTGAACCT CCTCCGGCAG CACCATGAGC TCTGCGACGT GGTTCTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	87.14	0.00e+00	971.00
IUUC-Apl-003577	Anas platyrhynchos	89.11	0.00e+00	969.00
IUUC-Ame-011433	Astyanax mexicanus	84.64	0.00e+00	886.00
IUUC-Bta-012650	Bos taurus	87.14	0.00e+00	971.00
IUUC-Cja-019878	Callithrix jacchus	86.56	0.00e+00	969.00
IUUC-Cfa-020936	Canis familiaris	87.14	0.00e+00	971.00
IUUC-Cpo-022212	Cavia porcellus	85.60	0.00e+00	958.00
IUUC-Csa-023372	Chlorocebus sabaeus	86.76	0.00e+00	969.00
IUUC-Cho-024885	Choloepus hoffmanni	88.96	7.00e-159	553.00
IUUC-Dno-029895	Dasypus novemcinctus	86.18	0.00e+00	961.00
IUUC-Ete-032703	Echinops telfairi	86.13	0.00e+00	823.00
IUUC-Eca-034150	Equus caballus	86.95	0.00e+00	969.00
IUUC-Eeu-035233	Erinaceus europaeus	86.37	0.00e+00	961.00
IUUC-Fca-036445	Felis catus	86.95	0.00e+00	967.00
IUUC-Fal-037156	Ficedula albicollis	81.77	0.00e+00	902.00
IUUC-Gmo-039158	Gadus morhua	84.45	0.00e+00	917.00
IUUC-Gga-040855	Gallus gallus	89.25	0.00e+00	995.00
IUUC-Gac-041294	Gasterosteus aculeatus	82.92	0.00e+00	902.00
IUUC-Ggo-045399	Gorilla gorilla	86.56	0.00e+00	968.00
IUUC-Hsa-046199	Homo sapiens	86.56	0.00e+00	968.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	85.99	0.00e+00	961.00
IUUC-Lch-049445	Latimeria chalumnae	87.92	0.00e+00	811.00
IUUC-Loc-052737	Lepisosteus oculatus	85.41	0.00e+00	914.00
IUUC-Laf-054173	Loxodonta africana	86.02	0.00e+00	960.00
IUUC-Mcc-055000	Macaca mulatta	86.56	0.00e+00	968.00
IUUC-Meu-056028	Macropus eugenii	83.95	4.00e-141	494.00
IUUC-Mga-059609	Meleagris gallopavo	89.38	0.00e+00	993.00
IUUC-Mmr-060842	Microcebus murinus	86.56	0.00e+00	967.00
IUUC-Mdo-062776	Monodelphis domestica	89.44	0.00e+00	966.00
IUUC-Mmu-063720	Mus musculus	86.37	0.00e+00	969.00
IUUC-Mpu-066723	Mustela putorius furo	89.63	2.00e-163	567.00
IUUC-Mlu-067403	Myotis lucifugus	85.60	0.00e+00	957.00
IUUC-Nle-069242	Nomascus leucogenys	85.99	0.00e+00	963.00
IUUC-Opr-070942	Ochotona princeps	88.96	1.00e-160	558.00
IUUC-Ont-072586	Oreochromis niloticus	84.45	0.00e+00	914.00
IUUC-Oan-073070	Ornithorhynchus anatinus	89.54	0.00e+00	952.00
IUUC-Ocu-074536	Oryctolagus cuniculus	86.76	0.00e+00	968.00
IUUC-Ola-086669	Oryzias latipes	69.57	0.00e+00	714.00
IUUC-Oga-088974	Otolemur garnettii	86.56	0.00e+00	968.00
IUUC-Oar-089544	Ovis aries	87.33	0.00e+00	972.00
IUUC-Ptr-091478	Pan troglodytes	86.18	0.00e+00	959.00
IUUC-Pan-092653	Papio anubis	86.56	0.00e+00	969.00
IUUC-Psi-094014	Pelodiscus sinensis	90.02	0.00e+00	1006.00
IUUC-Pfo-097316	Poecilia formosa	84.07	0.00e+00	909.00
IUUC-Pab-098609	Pongo abelii	86.37	0.00e+00	966.00
IUUC-Pva-102527	Pteropus vampyrus	89.30	7.00e-161	560.00
IUUC-Rno-105188	Rattus norvegicus	86.56	0.00e+00	969.00
IUUC-Sha-106543	Sarcophilus harrisii	89.64	0.00e+00	968.00
IUUC-Sar-113507	Sorex araneus	84.64	0.00e+00	951.00
IUUC-Ssc-115803	Sus scrofa	87.14	0.00e+00	972.00
IUUC-Tgu-116661	Taeniopygia guttata	80.20	0.00e+00	836.00
IUUC-Tru-118738	Takifugu rubripes	82.44	0.00e+00	898.00
IUUC-Tsy-119570	Tarsius syrichta	79.65	0.00e+00	867.00
IUUC-Tni-120041	Tetraodon nigroviridis	82.53	0.00e+00	902.00
IUUC-Tbe-127655	Tupaia belangeri	79.69	0.00e+00	854.00
IUUC-Ttr-129249	Tursiops truncatus	87.14	0.00e+00	969.00
IUUC-Vpa-130034	Vicugna pacos	86.18	0.00e+00	964.00
IUUC-Xtr-132964	Xenopus tropicalis	85.60	0.00e+00	950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence