iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134411

Ensembl Protein ID

CAG84041

UniProt Accession

Q6CGV2; Q6CGV2_YARLI

Genbank Protein ID

CAG84041.1

Protein Name

Histidine biosynthesis trifunctional protein; Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase; Histidinol dehydrogenase

Genbank Nucleotide ID

CR382127

Gene Name

YALI0_A15950g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_A15950g	CAG84041	CAG84041

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/NZF	24.68	4.90e+00	31.60	IUUC-Hsa-045963
UBD/Alpha-Helix/CUE	24.68	4.90e+00	31.60	IUUC-Hsa-045963

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Yarrowia lipolytica

Protein Sequence
(Fasta)

MFPLLPQVSS VTVPAVAVAP GKVLVSILQS DVPEIAKELK KAFGQAQFHI MADTDLSTDE 60
YIHLLDAGAS SVFVSGESAV DLAASGVPAG RLTVIGSKPD NLDVGGVFLK DTPALEDVAT 120

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Nucleotide Sequence
(Fasta)

ATGTTCCCCC TGCTGCCCCA AGTGAGCAGC GTGACTGTTC CGGCTGTGGC TGTGGCGCCC 60
GGCAAGGTGC TGGTGTCCAT TCTCCAGTCC GACGTCCCCG AGATCGCCAA GGAGCTCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0028--Amino-acid biosynthesis
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0368--Histidine biosynthesis
KW-0378--Hydrolase
KW-0520--NAD
KW-0547--Nucleotide-binding
KW-0560--Oxidoreductase
KW-1185--Reference proteome

Interpro

IPR016161--Ald_DH/histidinol_DH
IPR013785--Aldolase_TIM
IPR008179--HisE
IPR016298--Histidine_synth_trifunct
IPR001692--Histidinol_DH_CS
IPR012131--Hstdl_DH
IPR021130--PRib-ATP_PPHydrolase-like
IPR002496--PRib_AMP_CycHydrolase_dom

PROSITE

PS00611--HISOL_DEHYDROGENASE

Pfam

PF00815--Histidinol_dh
PF01502--PRA-CH
PF01503--PRA-PH

PRINTS

PR00083--HOLDHDRGNASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004399--F:histidinol dehydrogenase activity
GO:0051287--F:NAD binding
GO:0004635--F:phosphoribosyl-AMP cyclohydrolase activity
GO:0004636--F:phosphoribosyl-ATP diphosphatase activity
GO:0008270--F:zinc ion binding
GO:0000105--P:histidine biosynthetic process

KEGG

yli:YALI0A15950g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001681	Ailuropoda melanoleuca	22.88	7.00e-03	33.90
IUUC-Ago-007764	Ashbya gossypii	28.79	1.60e+00	26.20
IUUC-Cel-018279	Caenorhabditis elegans	45.16	5.50e-02	29.60
IUUC-Cja-020008	Callithrix jacchus	22.88	2.00e-03	35.40
IUUC-Cfa-020602	Canis familiaris	22.03	7.00e-03	33.90
IUUC-Cpo-022483	Cavia porcellus	22.58	4.00e-03	34.70
IUUC-Csa-024196	Chlorocebus sabaeus	22.88	3.00e-03	35.00
IUUC-Dor-030605	Dipodomys ordii	22.22	1.00e-03	36.20
IUUC-Eca-033410	Equus caballus	22.03	1.10e-02	33.10
IUUC-Eeu-034509	Erinaceus europaeus	22.03	8.00e-03	33.90
IUUC-Fca-035548	Felis catus	22.88	4.00e-03	35.00
IUUC-Gac-041841	Gasterosteus aculeatus	30.51	1.20e+00	27.30
IUUC-Ggo-044976	Gorilla gorilla	22.88	4.00e-03	34.70
IUUC-Hsa-045963	Homo sapiens	22.88	4.00e-03	34.70
IUUC-Itr-048861	Ictidomys tridecemlineatus	23.02	1.00e-03	35.80
IUUC-Mcc-054597	Macaca mulatta	22.88	3.00e-03	35.00
IUUC-Meu-056202	Macropus eugenii	20.34	2.70e-02	31.60
IUUC-Mmr-061047	Microcebus murinus	22.88	4.00e-03	34.70
IUUC-Mlu-067513	Myotis lucifugus	22.88	3.00e-03	35.00
IUUC-Oar-089573	Ovis aries	22.88	5.00e-03	34.30
IUUC-Ptr-091270	Pan troglodytes	22.88	4.00e-03	34.70
IUUC-Pan-092250	Papio anubis	22.88	3.00e-03	35.00
IUUC-Pab-098776	Pongo abelii	22.88	3.00e-03	35.00
IUUC-Pva-103025	Pteropus vampyrus	22.03	6.00e-03	34.30
IUUC-Sar-113207	Sorex araneus	22.03	1.20e-02	33.10
IUUC-Tbe-127934	Tupaia belangeri	22.88	3.00e-03	35.00
IUUC-Ttr-128519	Tursiops truncatus	22.88	6.00e-03	33.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence