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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105660
Ensembl Protein ID ENSRNOP00000069442.1
UniProt Accession A0A0G2JVD6; A0A0G2JVD6_RAT
Genbank Protein ID ENSRNOP00000069442
Protein Name Lysine methyltransferase 2D
Genbank Nucleotide ID AC114446
Gene Name Kmt2d
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000061499.1 ENSRNOT00000077502.1 ENSRNOP00000069442.1
ENSRNOG00000061499.1 ENSRNOT00000083354.1 ENSRNOP00000070458.1
ENSRNOG00000061499.1 ENSRNOT00000089544.1 ENSRNOP00000074816.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFACRAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.60e-27 95.2 1462 1513
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C++C++++ +e+ l++C++C++w+H++C +l  e+e+++  +  + C +C+
   Q: 1462 TCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDEVEQAADegFDCVSCQ 1513
           6********************************888888877778******7 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MDSQKPPAED KDSDPAADGL AAPEKPGATE PHLPILCIGE VSVPSSGSSR LQKPPHDCSG 60
GPARRCALCN CGEPSLHGQR ELQRFELPSD WPGFPVVSSG GSSGPCEAVL PNEDLSQIGF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105660|E3,PHD|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGGGGCGCT GGCCGGGCCC TAGGACTGAG AGGCCGCCCC GCGACGCGGA TGCGGAGCCT 60
GCTTGCCCAA GATCAAAGCC ACCGGTGCTC TCTTTGTGTC CGCTCGGGAT TCGCCGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105660|E3,PHD|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000644--CBS_dom
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51371--CBS
PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00571--CBS
PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00116--CBS
SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00184--RING
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0008284--P:positive regulation of cell proliferation
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001806 Ailuropoda melanoleuca 89.13 0.00e+00 3438.00
IUUC-Apl-003311 Anas platyrhynchos 71.71 0.00e+00 823.00
IUUC-Aca-005364 Anolis carolinensis 50.68 0.00e+00 1233.00
IUUC-Ame-010612 Astyanax mexicanus 80.59 0.00e+00 939.00
IUUC-Bta-013011 Bos taurus 86.40 0.00e+00 3347.00
IUUC-Cel-018354 Caenorhabditis elegans 37.35 7.00e-64 240.00
IUUC-Cja-019841 Callithrix jacchus 88.39 0.00e+00 3519.00
IUUC-Cfa-021131 Canis familiaris 88.84 0.00e+00 3528.00
IUUC-Cpo-021957 Cavia porcellus 85.82 0.00e+00 3631.00
IUUC-Csa-023722 Chlorocebus sabaeus 88.40 0.00e+00 3466.00
IUUC-Dre-028110 Danio rerio 65.54 0.00e+00 767.00
IUUC-Dno-029932 Dasypus novemcinctus 89.17 0.00e+00 1595.00
IUUC-Dor-030192 Dipodomys ordii 83.89 0.00e+00 1671.00
IUUC-Ete-032572 Echinops telfairi 82.71 0.00e+00 1918.00
IUUC-Eca-034166 Equus caballus 90.02 3.00e-177 615.00
IUUC-Eeu-034848 Erinaceus europaeus 90.24 0.00e+00 1285.00
IUUC-Fca-035424 Felis catus 88.00 0.00e+00 3488.00
IUUC-Fal-037179 Ficedula albicollis 66.72 0.00e+00 1134.00
IUUC-Gmo-038719 Gadus morhua 80.21 0.00e+00 833.00
IUUC-Gga-040815 Gallus gallus 57.69 0.00e+00 1840.00
IUUC-Gac-042436 Gasterosteus aculeatus 77.92 0.00e+00 917.00
IUUC-Ggo-044711 Gorilla gorilla 88.50 0.00e+00 3448.00
IUUC-Hsa-046567 Homo sapiens 88.50 0.00e+00 3415.00
IUUC-Itr-048510 Ictidomys tridecemlineatus 87.73 0.00e+00 3520.00
IUUC-Lch-050086 Latimeria chalumnae 72.41 0.00e+00 808.00
IUUC-Loc-051979 Lepisosteus oculatus 81.27 0.00e+00 979.00
IUUC-Laf-054377 Loxodonta africana 86.44 0.00e+00 3436.00
IUUC-Mcc-055577 Macaca mulatta 87.50 0.00e+00 3385.00
IUUC-Meu-055992 Macropus eugenii 82.99 0.00e+00 1280.00
IUUC-Mmr-061772 Microcebus murinus 85.53 0.00e+00 3442.00
IUUC-Mdo-062876 Monodelphis domestica 81.66 0.00e+00 1113.00
IUUC-Mmu-063903 Mus musculus 94.21 0.00e+00 3769.00
IUUC-Mpu-066700 Mustela putorius furo 88.06 0.00e+00 3447.00
IUUC-Mlu-068180 Myotis lucifugus 87.66 0.00e+00 3509.00
IUUC-Nle-069362 Nomascus leucogenys 88.54 0.00e+00 3438.00
IUUC-Opr-070304 Ochotona princeps 84.37 0.00e+00 3307.00
IUUC-Ont-071881 Oreochromis niloticus 62.66 0.00e+00 1289.00
IUUC-Oan-073663 Ornithorhynchus anatinus 86.05 0.00e+00 909.00
IUUC-Ocu-074053 Oryctolagus cuniculus 83.28 0.00e+00 3461.00
IUUC-Ola-086384 Oryzias latipes 77.16 0.00e+00 937.00
IUUC-Oga-088450 Otolemur garnettii 87.01 0.00e+00 3547.00
IUUC-Oar-089975 Ovis aries 90.80 0.00e+00 1911.00
IUUC-Ptr-091073 Pan troglodytes 88.29 0.00e+00 3448.00
IUUC-Pan-092871 Papio anubis 86.65 0.00e+00 3445.00
IUUC-Pma-094252 Petromyzon marinus 39.65 2.00e-133 471.00
IUUC-Pfo-097525 Poecilia formosa 78.16 0.00e+00 901.00
IUUC-Pab-097679 Pongo abelii 88.55 0.00e+00 3466.00
IUUC-Pca-100499 Procavia capensis 88.35 0.00e+00 2075.00
IUUC-Pva-102898 Pteropus vampyrus 87.71 0.00e+00 3399.00
IUUC-Sha-107431 Sarcophilus harrisii 78.65 0.00e+00 2963.00
IUUC-Sly-111765 Solanum lycopersicum 30.46 1.00e-23 103.00
IUUC-Sar-113183 Sorex araneus 73.87 2.00e-88 323.00
IUUC-Sbi-113816 Sorghum bicolor 31.43 6.00e-14 73.20
IUUC-Ssc-115678 Sus scrofa 87.52 0.00e+00 3339.00
IUUC-Tgu-116677 Taeniopygia guttata 71.89 0.00e+00 827.00
IUUC-Tru-117922 Takifugu rubripes 78.88 0.00e+00 935.00
IUUC-Tsy-118905 Tarsius syrichta 80.29 0.00e+00 1533.00
IUUC-Tni-119970 Tetraodon nigroviridis 58.46 0.00e+00 680.00
IUUC-Tbe-127625 Tupaia belangeri 74.31 3.00e-147 518.00
IUUC-Ttr-129162 Tursiops truncatus 88.50 0.00e+00 2003.00
IUUC-Xtr-132455 Xenopus tropicalis 62.05 0.00e+00 1204.00
Created Date 25-Jun-2017

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