iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107031

Ensembl Protein ID

ENSSHAP00000006479.1

UniProt Accession

G3VTH4; G3VTH4_SARHA

Genbank Protein ID

ENSSHAP00000006479

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AEFK01138882

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005638.1	ENSSHAT00000006535.1	ENSSHAP00000006479.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	37.2	177	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 177  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 224
           69*.*******99..*********99***********...999997.******87 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

VSGIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKNLSPEQ RVEHLQKIQN 60
AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKEKMEGSDL ESSGGRGLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCAGGTA TTGAAAACCT TCCATGTGAA CTCCAAAGGA ATTTCCAGCT GATGCGGGAA 60
CTGGATCAGA GAACAGAAGG TGTGTGCAGG TACTCCGGGA AGCAGCCAGG AAAGAGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	96.05	2.00e-109	388.00
IUUC-Atr-002906	Amborella trichopoda	32.50	8.00e-32	130.00
IUUC-Apl-003516	Anas platyrhynchos	90.20	3.00e-96	343.00
IUUC-Aca-005009	Anolis carolinensis	84.72	6.00e-101	359.00
IUUC-Ame-011879	Astyanax mexicanus	76.19	3.00e-96	344.00
IUUC-Bta-012590	Bos taurus	93.83	2.00e-111	394.00
IUUC-Bol-015245	Brassica oleracea	33.76	2.00e-30	125.00
IUUC-Bra-017027	Brassica rapa	34.18	1.00e-30	126.00
IUUC-Cja-019518	Callithrix jacchus	93.91	1.00e-112	398.00
IUUC-Cfa-020620	Canis familiaris	94.35	1.00e-116	411.00
IUUC-Cpo-022085	Cavia porcellus	93.91	1.00e-109	388.00
IUUC-Csa-023421	Chlorocebus sabaeus	95.22	9.00e-110	389.00
IUUC-Dre-027588	Danio rerio	75.86	3.00e-96	343.00
IUUC-Eca-033493	Equus caballus	92.95	2.00e-112	397.00
IUUC-Fca-035635	Felis catus	95.45	2.00e-56	211.00
IUUC-Fal-036998	Ficedula albicollis	90.00	7.00e-112	395.00
IUUC-Gmo-039035	Gadus morhua	74.89	1.00e-91	328.00
IUUC-Gga-040578	Gallus gallus	89.13	2.00e-111	394.00
IUUC-Gac-042172	Gasterosteus aculeatus	74.03	4.00e-95	340.00
IUUC-Hsa-045965	Homo sapiens	95.22	9.00e-110	389.00
IUUC-Loc-052725	Lepisosteus oculatus	81.30	3.00e-93	333.00
IUUC-Mcc-055455	Macaca mulatta	96.49	4.00e-110	390.00
IUUC-Mtr-058089	Medicago truncatula	32.07	2.00e-34	138.00
IUUC-Mga-059312	Meleagris gallopavo	90.10	7.00e-97	345.00
IUUC-Mmr-061351	Microcebus murinus	96.04	8.00e-109	385.00
IUUC-Mdo-062282	Monodelphis domestica	97.39	3.00e-112	397.00
IUUC-Mmu-063201	Mus musculus	90.87	4.00e-109	386.00
IUUC-Mpu-066302	Mustela putorius furo	94.35	7.00e-110	389.00
IUUC-Mlu-068192	Myotis lucifugus	93.91	2.00e-110	390.00
IUUC-Ont-072055	Oreochromis niloticus	75.65	5.00e-92	330.00
IUUC-Oan-073652	Ornithorhynchus anatinus	96.96	1.00e-116	412.00
IUUC-Ocu-073871	Oryctolagus cuniculus	93.07	3.00e-111	394.00
IUUC-Oin-079049	Oryza indica	34.90	2.00e-33	135.00
IUUC-Oni-082218	Oryza nivara	34.90	2.00e-33	135.00
IUUC-Ola-087103	Oryzias latipes	75.00	2.00e-88	318.00
IUUC-Oga-088066	Otolemur garnettii	87.44	1.00e-93	335.00
IUUC-Ptr-091665	Pan troglodytes	95.22	9.00e-110	389.00
IUUC-Pan-091875	Papio anubis	95.22	9.00e-110	389.00
IUUC-Psi-093904	Pelodiscus sinensis	93.43	1.00e-102	365.00
IUUC-Pfo-096981	Poecilia formosa	75.76	2.00e-91	328.00
IUUC-Pva-102282	Pteropus vampyrus	86.96	3.00e-111	393.00
IUUC-Rno-105646	Rattus norvegicus	90.87	7.00e-109	385.00
IUUC-Smo-109441	Selaginella moellendorffii	34.71	7.00e-40	156.00
IUUC-Sly-111750	Solanum lycopersicum	34.18	4.00e-33	134.00
IUUC-Stu-112250	Solanum tuberosum	34.18	4.00e-33	134.00
IUUC-Tgu-116837	Taeniopygia guttata	89.57	4.00e-111	393.00
IUUC-Tru-117974	Takifugu rubripes	75.00	2.00e-88	318.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.32	1.00e-81	295.00
IUUC-Tca-121597	Theobroma cacao	34.62	2.00e-31	128.00
IUUC-Vvi-131487	Vitis vinifera	34.60	4.00e-34	137.00
IUUC-Xtr-132189	Xenopus tropicalis	82.10	5.00e-102	363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence