iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066854

Ensembl Protein ID

ENSMPUP00000014047.1

UniProt Accession

M3YRT7; M3YRT7_MUSPF

Genbank Protein ID

ENSMPUP00000014047

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01021286

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000014154.1	ENSMPUT00000014270.1	ENSMPUP00000014047.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.50e-06	25.8	15	72
E3 activity/RING/RING	2.30e-06	28.0	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
            +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 15   RLLCPLCGKPMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 72
           689*************999*****************99*********99999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLA IRCIHSEEGC RWSGPLRHLQ SHLNACSFNV IPCPNRCPTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNCTCGCCCG TGCCCGCTGT 60
CCACCCGCCA TGCCCGGCTT CGACTACAAG TTCCTTGAGA AGCCCAAGCG GCGGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	97.65	0.00e+00	907.00
IUUC-Atr-003147	Amborella trichopoda	27.47	2.00e-06	46.20
IUUC-Ath-007062	Arabidopsis thaliana	32.67	4.00e-07	50.10
IUUC-Ame-011530	Astyanax mexicanus	77.66	0.00e+00	773.00
IUUC-Bta-013582	Bos taurus	97.87	0.00e+00	919.00
IUUC-Bdi-014617	Brachypodium distachyon	25.18	1.00e-06	49.30
IUUC-Cja-019883	Callithrix jacchus	93.75	2.00e-51	193.00
IUUC-Cfa-020133	Canis familiaris	93.40	0.00e+00	861.00
IUUC-Cpo-022021	Cavia porcellus	97.23	0.00e+00	916.00
IUUC-Csa-023199	Chlorocebus sabaeus	97.45	0.00e+00	919.00
IUUC-Dre-028193	Danio rerio	76.81	0.00e+00	769.00
IUUC-Dno-028917	Dasypus novemcinctus	97.87	0.00e+00	920.00
IUUC-Ete-032433	Echinops telfairi	96.38	0.00e+00	908.00
IUUC-Fca-036155	Felis catus	98.94	0.00e+00	926.00
IUUC-Gmo-038860	Gadus morhua	76.81	0.00e+00	765.00
IUUC-Gga-041052	Gallus gallus	82.13	0.00e+00	836.00
IUUC-Gac-041489	Gasterosteus aculeatus	76.81	0.00e+00	764.00
IUUC-Ggo-044996	Gorilla gorilla	97.23	0.00e+00	914.00
IUUC-Hsa-046252	Homo sapiens	97.45	0.00e+00	916.00
IUUC-Hvu-047127	Hordeum vulgare	39.44	4.00e-08	52.00
IUUC-Itr-048232	Ictidomys tridecemlineatus	97.66	0.00e+00	919.00
IUUC-Kpa-049340	Komagataella pastoris	26.91	4.00e-16	79.30
IUUC-Loc-052312	Lepisosteus oculatus	77.49	0.00e+00	770.00
IUUC-Laf-054376	Loxodonta africana	98.09	0.00e+00	922.00
IUUC-Mcc-055684	Macaca mulatta	97.45	0.00e+00	919.00
IUUC-Mmr-061198	Microcebus murinus	97.66	0.00e+00	918.00
IUUC-Mdo-062585	Monodelphis domestica	88.09	0.00e+00	837.00
IUUC-Mmu-064303	Mus musculus	96.60	0.00e+00	913.00
IUUC-Mac-064529	Musa acuminata	29.60	4.00e-10	58.90
IUUC-Nle-070098	Nomascus leucogenys	96.17	0.00e+00	904.00
IUUC-Ont-071518	Oreochromis niloticus	76.97	0.00e+00	764.00
IUUC-Ocu-073841	Oryctolagus cuniculus	97.45	0.00e+00	917.00
IUUC-Ola-086674	Oryzias latipes	77.19	0.00e+00	765.00
IUUC-Oga-088510	Otolemur garnettii	97.87	0.00e+00	920.00
IUUC-Oar-089225	Ovis aries	94.04	0.00e+00	874.00
IUUC-Pan-092725	Papio anubis	97.45	0.00e+00	919.00
IUUC-Pfo-096341	Poecilia formosa	76.76	0.00e+00	766.00
IUUC-Ppe-101708	Prunus persica	30.16	2.00e-07	52.40
IUUC-Pva-103131	Pteropus vampyrus	98.85	3.00e-143	501.00
IUUC-Rno-105996	Rattus norvegicus	96.81	0.00e+00	913.00
IUUC-Sly-111800	Solanum lycopersicum	30.83	1.00e-06	49.30
IUUC-Tru-117602	Takifugu rubripes	77.45	0.00e+00	774.00
IUUC-Tae-123531	Triticum aestivum	25.41	4.00e-06	47.40
IUUC-Tur-126067	Triticum urartu	40.85	3.00e-08	52.80
IUUC-Ttr-128370	Tursiops truncatus	97.59	0.00e+00	722.00
IUUC-Vvi-131592	Vitis vinifera	31.19	6.00e-07	50.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence