iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007146

UUCD1 version

UUC-ArT-00556

Ensembl Protein ID

AT2G45910.2

UniProt Accession

Q8GUH1; O80828; PUB33_ARATH

Genbank Protein ID

AAC28534.1; AEC10616.1; ANM61922.1; AAO00872.1; BAE99173.1

Protein Name

U-box domain-containing protein 33; Plant U-box protein 33; E3 ubiquitin ligase; RING-type E3 ubiquitin transferase; Serine/threonine-protein kinase

Genbank Nucleotide ID

AC004665; CP002685; CP002685; BT002512; AK227123

Gene Name

PUB33; At2g45910; F4I18.11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G45910	AT2G45910.2	AT2G45910.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.10e-25	89.5	764	833

Active Site

Position(s)	Description	Evidence
603	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU00159, ECO:0000255\|PROSITE-ProRule:PRU10027}

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
           p++f+CpI  e+M+dP+v+++G ty++++I+ wl+s + t+P+t+ +l++++l+ n++lr+ iq+w++ +
   Q: 764  PPYFICPIFQEVMQDPHVAADGFTYEAEAIRAWLDSEHDTSPMTNVKLSHTSLIANHALRSAIQEWLQHH 833
           99*****************************************************************987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MALVSPIPAM GERAGSMRFH GIGSPGSRSS RSGIMDEPVS RLIDEKIFVA VDKHVAKSKS 60
TLIWALQNTG GKKICLIHVH QPSQMIPLMG AKFPVGAVKE EEVRVFREKE REKVHMILDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACCACGTC AGATTTTTTA GCAGCAAAGC ACACAAATCC CCAAGAAGCT TCGTTTTGGT 60
ATGTTAAAGT AAAATCGAAT AAATTTTGCA CACAAATCTC AATTTTAATT GTCTTTCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR014729--Rossmann-like_a/b/a_fold
IPR008271--Ser/Thr_kinase_AS
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS51698--U_BOX

Pfam

PF00069--Pkinase
PF04564--U-box

SMART

SM00220--S_TKc
SM00504--Ubox

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ath:AT2G45910

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000187	Aegilops tauschii	42.42	3.00e-161	561.00
IUUC-Atr-002778	Amborella trichopoda	43.39	0.00e+00	644.00
IUUC-Apl-004134	Anas platyrhynchos	31.35	9.00e-23	100.00
IUUC-Aly-005712	Arabidopsis lyrata	97.84	0.00e+00	1568.00
IUUC-Bdi-014983	Brachypodium distachyon	41.81	4.00e-178	617.00
IUUC-Bol-016049	Brassica oleracea	81.11	0.00e+00	1264.00
IUUC-Bra-017486	Brassica rapa	81.46	0.00e+00	1311.00
IUUC-Cel-018594	Caenorhabditis elegans	31.47	4.00e-22	99.00
IUUC-Cfa-020060	Canis familiaris	31.91	2.00e-22	100.00
IUUC-Cho-025014	Choloepus hoffmanni	31.23	6.00e-22	98.20
IUUC-Cin-025114	Ciona intestinalis	31.96	2.00e-20	93.20
IUUC-Dor-030202	Dipodomys ordii	33.68	9.00e-23	100.00
IUUC-Ete-033170	Echinops telfairi	34.54	4.00e-22	98.60
IUUC-Eca-033970	Equus caballus	31.91	8.00e-23	101.00
IUUC-Fal-036753	Ficedula albicollis	30.53	2.00e-23	104.00
IUUC-Gga-040283	Gallus gallus	30.15	3.00e-23	103.00
IUUC-Gac-041536	Gasterosteus aculeatus	30.00	2.00e-26	114.00
IUUC-Gma-043336	Glycine max	53.65	0.00e+00	905.00
IUUC-Hvu-047310	Hordeum vulgare	43.66	0.00e+00	647.00
IUUC-Lpe-051291	Leersia perrieri	48.59	4.00e-138	484.00
IUUC-Loc-052286	Lepisosteus oculatus	31.12	4.00e-24	105.00
IUUC-Laf-053977	Loxodonta africana	31.91	1.00e-22	100.00
IUUC-Mtr-058733	Medicago truncatula	55.44	0.00e+00	913.00
IUUC-Mga-060135	Meleagris gallopavo	31.91	2.00e-22	99.80
IUUC-Mmr-061168	Microcebus murinus	31.91	9.00e-23	100.00
IUUC-Mac-064649	Musa acuminata	44.84	0.00e+00	634.00
IUUC-Nle-070178	Nomascus leucogenys	31.91	1.00e-22	100.00
IUUC-Opr-070705	Ochotona princeps	30.31	3.00e-21	95.90
IUUC-Oan-072997	Ornithorhynchus anatinus	33.68	1.00e-22	100.00
IUUC-Oba-075737	Oryza barthii	41.43	1.00e-175	610.00
IUUC-Obr-076707	Oryza brachyantha	42.67	0.00e+00	629.00
IUUC-Ogl-077374	Oryza glaberrima	47.85	2.00e-135	476.00
IUUC-Ogu-078239	Oryza glumaepatula	47.85	4.00e-135	474.00
IUUC-Oin-079180	Oryza indica	42.32	0.00e+00	638.00
IUUC-Olo-080937	Oryza longistaminata	42.38	1.00e-162	567.00
IUUC-Ome-081468	Oryza meridionalis	41.58	0.00e+00	628.00
IUUC-Oni-082541	Oryza nivara	42.32	0.00e+00	638.00
IUUC-Opu-083566	Oryza punctata	41.36	0.00e+00	628.00
IUUC-Oru-085132	Oryza rufipogon	42.43	3.00e-180	625.00
IUUC-Osa-086151	Oryza sativa	48.04	5.00e-136	478.00
IUUC-Ola-086953	Oryzias latipes	33.86	9.00e-25	107.00
IUUC-Oar-090279	Ovis aries	31.52	5.00e-22	98.60
IUUC-Psi-093071	Pelodiscus sinensis	31.91	2.00e-22	99.80
IUUC-Pma-094232	Petromyzon marinus	31.75	2.00e-23	103.00
IUUC-Pfo-096763	Poecilia formosa	29.32	3.00e-25	110.00
IUUC-Pop-099554	Populus trichocarpa	57.70	0.00e+00	889.00
IUUC-Pca-100245	Procavia capensis	31.47	4.00e-22	99.00
IUUC-Ppe-101646	Prunus persica	66.48	0.00e+00	691.00
IUUC-Sha-107539	Sarcophilus harrisii	32.30	1.00e-22	100.00
IUUC-Sit-110219	Setaria italica	43.03	0.00e+00	635.00
IUUC-Sly-111528	Solanum lycopersicum	50.53	0.00e+00	822.00
IUUC-Stu-112831	Solanum tuberosum	62.67	0.00e+00	644.00
IUUC-Sar-113364	Sorex araneus	31.09	6.00e-18	85.10
IUUC-Sbi-114291	Sorghum bicolor	43.47	0.00e+00	628.00
IUUC-Tgu-117380	Taeniopygia guttata	33.16	8.00e-22	97.80
IUUC-Tru-117541	Takifugu rubripes	30.00	1.00e-26	114.00
IUUC-Tni-119938	Tetraodon nigroviridis	29.67	2.00e-25	110.00
IUUC-Tca-121389	Theobroma cacao	67.83	0.00e+00	692.00
IUUC-Tae-125058	Triticum aestivum	42.62	0.00e+00	631.00
IUUC-Tur-126824	Triticum urartu	46.21	8.00e-137	480.00
IUUC-Vpa-130815	Vicugna pacos	31.23	8.00e-22	97.80
IUUC-Vvi-131057	Vitis vinifera	53.40	0.00e+00	916.00
IUUC-Xtr-132322	Xenopus tropicalis	34.20	9.00e-23	100.00
IUUC-Xma-133720	Xiphophorus maculatus	29.32	2.00e-25	110.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence