iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115827

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 22

Genbank Nucleotide ID

CU606992

Gene Name

LOC100156352; KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000010108.2	ENSSSCT00000011069.2	ENSSSCP00000010781.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-19	69.9	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.60e-07	28.1	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +N l+++r+A+l+d+++L ++ + +ilk+F
   Q: 150  DNILDVYRLAELFDLSRLTEQLDAYILKNF 179
           8***************************** PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAEEQEFAQL CKLPTQPSHP HCVSNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACGTAAGG CACCGAAGCC CCGCCCCGCG CCCCGCCCCG CCCCCGCGAG TGCGGCCTCA 60
GCTTGCAGCT GCGCCAGGTG AGCGACCAGC GCCGGTCAGC GCGGGTTCCC TTGCGGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

ssc:100156352

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	95.74	0.00e+00	1215.00
IUUC-Apl-004081	Anas platyrhynchos	77.12	0.00e+00	1014.00
IUUC-Aca-005015	Anolis carolinensis	65.97	0.00e+00	845.00
IUUC-Ame-011712	Astyanax mexicanus	59.56	0.00e+00	711.00
IUUC-Bta-012594	Bos taurus	95.74	0.00e+00	1243.00
IUUC-Cja-019752	Callithrix jacchus	94.85	0.00e+00	1011.00
IUUC-Cfa-020884	Canis familiaris	96.06	0.00e+00	1255.00
IUUC-Cpo-021711	Cavia porcellus	94.48	0.00e+00	1239.00
IUUC-Csa-023211	Chlorocebus sabaeus	96.06	0.00e+00	1252.00
IUUC-Dre-028395	Danio rerio	60.10	0.00e+00	744.00
IUUC-Dno-030096	Dasypus novemcinctus	92.16	0.00e+00	1206.00
IUUC-Dor-030709	Dipodomys ordii	93.24	0.00e+00	691.00
IUUC-Eca-033388	Equus caballus	95.74	0.00e+00	1252.00
IUUC-Eeu-034616	Erinaceus europaeus	84.07	0.00e+00	1084.00
IUUC-Fca-035815	Felis catus	95.90	0.00e+00	1253.00
IUUC-Fal-037311	Ficedula albicollis	79.51	0.00e+00	997.00
IUUC-Gmo-039571	Gadus morhua	52.08	8.00e-156	543.00
IUUC-Gga-040992	Gallus gallus	76.96	0.00e+00	1014.00
IUUC-Gac-042041	Gasterosteus aculeatus	54.55	0.00e+00	673.00
IUUC-Ggo-045141	Gorilla gorilla	90.38	0.00e+00	1177.00
IUUC-Hsa-045984	Homo sapiens	96.21	0.00e+00	1256.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	95.58	0.00e+00	1253.00
IUUC-Lch-049700	Latimeria chalumnae	59.91	0.00e+00	724.00
IUUC-Loc-052141	Lepisosteus oculatus	61.20	0.00e+00	802.00
IUUC-Laf-053487	Loxodonta africana	93.97	0.00e+00	1212.00
IUUC-Mcc-054682	Macaca mulatta	95.14	0.00e+00	998.00
IUUC-Meu-055937	Macropus eugenii	73.82	0.00e+00	954.00
IUUC-Mga-059953	Meleagris gallopavo	76.96	0.00e+00	1014.00
IUUC-Mmr-061743	Microcebus murinus	95.43	0.00e+00	1240.00
IUUC-Mdo-062328	Monodelphis domestica	82.60	0.00e+00	1079.00
IUUC-Mmu-063979	Mus musculus	93.30	0.00e+00	1205.00
IUUC-Mpu-066750	Mustela putorius furo	96.06	0.00e+00	1254.00
IUUC-Mlu-066960	Myotis lucifugus	93.69	0.00e+00	1220.00
IUUC-Nle-069690	Nomascus leucogenys	96.23	0.00e+00	1125.00
IUUC-Opr-071059	Ochotona princeps	88.98	0.00e+00	1138.00
IUUC-Ont-072004	Oreochromis niloticus	57.46	0.00e+00	676.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.41	0.00e+00	734.00
IUUC-Ocu-074310	Oryctolagus cuniculus	95.83	3.00e-155	540.00
IUUC-Ola-086599	Oryzias latipes	57.02	0.00e+00	689.00
IUUC-Oga-087980	Otolemur garnettii	94.79	0.00e+00	1235.00
IUUC-Oar-089956	Ovis aries	80.29	0.00e+00	931.00
IUUC-Ptr-090598	Pan troglodytes	96.06	0.00e+00	1128.00
IUUC-Pan-092387	Papio anubis	94.94	0.00e+00	999.00
IUUC-Psi-093484	Pelodiscus sinensis	78.21	0.00e+00	1045.00
IUUC-Pma-094224	Petromyzon marinus	50.08	3.00e-173	601.00
IUUC-Pfo-096149	Poecilia formosa	57.46	0.00e+00	707.00
IUUC-Pab-098097	Pongo abelii	96.06	0.00e+00	1255.00
IUUC-Pva-103174	Pteropus vampyrus	95.06	4.00e-155	541.00
IUUC-Rno-105350	Rattus norvegicus	93.83	0.00e+00	1192.00
IUUC-Sha-106817	Sarcophilus harrisii	83.52	9.00e-135	473.00
IUUC-Tgu-116748	Taeniopygia guttata	81.37	0.00e+00	891.00
IUUC-Tru-118644	Takifugu rubripes	57.32	0.00e+00	681.00
IUUC-Tsy-118888	Tarsius syrichta	89.25	0.00e+00	1025.00
IUUC-Tni-120060	Tetraodon nigroviridis	53.93	8.00e-173	600.00
IUUC-Ttr-129183	Tursiops truncatus	97.67	0.00e+00	1136.00
IUUC-Xtr-132780	Xenopus tropicalis	67.75	0.00e+00	888.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence