iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027995

UUCD1 version

UUC-DaR-00958

Ensembl Protein ID

ENSDARP00000122949.2

UniProt Accession

F1R598; F1QW00; F1R598_DANRE

Genbank Protein ID

ENSDARP00000122949

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

BX324233

Gene Name

kmt2cb

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000075560.5	ENSDART00000131780.2	ENSDARP00000122949.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.80e-30	103.4	377	427

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 1    ekvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           +kvC  C+e+ged+ ++++C+ C++ +H  Clk++  ++ p++  w C++Cr +
   Q: 377  CKVCQTCKEPGEDT-KMLVCDVCDKGYHTFCLKPA-MDSIPTNG-WRCKNCRMC 427
           57999999999987.6*******************.9******8.******965 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSSEEKSLDP SDKGPSPPPC SSGATPTGSP TPTDKRPRGR PRKDALSTAT SIPSVPRQRK 60
KNRGRGKALV EDEDSTDGME TAETGSTQET VAKGQQEETE DASAMAVSAE GEEEEQSSSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATGCGGT TACACTCAAA TATGGCTACC ATGGAGTGAG AGCTACAACT TTAATATTTG 60
TAGTAATGCC GAAATGTAAC GTTTTATTTA ATTTTCCGTT CTACAGCCGC GTCTAAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR000637--HMGI/Y_DNA-bd_CS
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS00354--HMGI_Y
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Eca-033945	Equus caballus	50.22	0.00e+00	1191.00
IUUC-Gmo-039403	Gadus morhua	54.23	0.00e+00	1786.00
IUUC-Gac-041896	Gasterosteus aculeatus	52.40	0.00e+00	2444.00
IUUC-Lch-050086	Latimeria chalumnae	42.48	0.00e+00	1657.00
IUUC-Mlu-068201	Myotis lucifugus	51.48	0.00e+00	1201.00
IUUC-Ola-086436	Oryzias latipes	50.48	0.00e+00	2696.00
IUUC-Tru-118037	Takifugu rubripes	54.73	0.00e+00	1755.00
IUUC-Tni-119970	Tetraodon nigroviridis	52.34	0.00e+00	1640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence