iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116677

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

ABQF01040433

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000000616.1	ENSTGUT00000000652.1	ENSTGUP00000000641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-31	108.3	813	864

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
            C++C ++++de+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 813  TCPICYRTYRDEELIIQCRQCDRWMHAICQNLNTEEEVENIADmgFDCTICR 864
           6***************************************99999******8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

QRCAFCKHLG ATIKCCEEKC TQMYHYPCAA GAGTFQDFSN LSLLCPDHID QAPERSKEEA 60
NCAVCDSPGD LLDQLFCTTC GQHYHGMCLD IQVTPLKRAG WQCPDCKVCQ NCKHSGEDNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCGATGTG CATTTTGTAA GCACCTTGGA GCCACTATCA AATGCTGTGA AGAGAAATGT 60
ACCCAGATGT ACCATTACCC CTGTGCTGCT GGAGCAGGCA CATTTCAGGA TTTCAGTAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	72.28	0.00e+00	5512.00
IUUC-Apl-003311	Anas platyrhynchos	90.17	0.00e+00	7201.00
IUUC-Aca-004705	Anolis carolinensis	70.99	0.00e+00	5464.00
IUUC-Ame-010612	Astyanax mexicanus	72.88	0.00e+00	866.00
IUUC-Bta-012322	Bos taurus	69.97	0.00e+00	5222.00
IUUC-Bol-015791	Brassica oleracea	34.03	6.00e-29	122.00
IUUC-Bra-017422	Brassica rapa	34.03	2.00e-29	123.00
IUUC-Cel-018354	Caenorhabditis elegans	35.67	2.00e-65	245.00
IUUC-Cja-019983	Callithrix jacchus	72.46	0.00e+00	5678.00
IUUC-Cfa-020903	Canis familiaris	71.18	0.00e+00	5537.00
IUUC-Cpo-021732	Cavia porcellus	66.67	0.00e+00	3651.00
IUUC-Csa-023083	Chlorocebus sabaeus	67.95	0.00e+00	3925.00
IUUC-Cho-024469	Choloepus hoffmanni	65.50	0.00e+00	1713.00
IUUC-Dre-028110	Danio rerio	64.55	0.00e+00	1238.00
IUUC-Dno-029932	Dasypus novemcinctus	74.39	0.00e+00	893.00
IUUC-Dor-030569	Dipodomys ordii	68.61	0.00e+00	3615.00
IUUC-Dme-031590	Drosophila melanogaster	33.47	2.00e-70	260.00
IUUC-Ete-032572	Echinops telfairi	75.86	0.00e+00	765.00
IUUC-Eca-033945	Equus caballus	69.37	0.00e+00	3658.00
IUUC-Eeu-034848	Erinaceus europaeus	40.49	1.00e-142	502.00
IUUC-Fca-035922	Felis catus	70.76	0.00e+00	5353.00
IUUC-Fal-037179	Ficedula albicollis	75.73	0.00e+00	868.00
IUUC-Gmo-039403	Gadus morhua	54.74	0.00e+00	1228.00
IUUC-Gga-040815	Gallus gallus	54.22	2.00e-115	412.00
IUUC-Gac-041896	Gasterosteus aculeatus	50.00	0.00e+00	1393.00
IUUC-Ggo-044812	Gorilla gorilla	70.19	0.00e+00	5485.00
IUUC-Hsa-046595	Homo sapiens	72.21	0.00e+00	5657.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	71.24	0.00e+00	5423.00
IUUC-Lch-050086	Latimeria chalumnae	59.53	0.00e+00	2532.00
IUUC-Loc-052891	Lepisosteus oculatus	54.79	0.00e+00	1804.00
IUUC-Laf-054348	Loxodonta africana	69.13	0.00e+00	2470.00
IUUC-Mcc-054868	Macaca mulatta	72.41	0.00e+00	5629.00
IUUC-Meu-056322	Macropus eugenii	62.43	0.00e+00	1102.00
IUUC-Mga-059541	Meleagris gallopavo	90.18	0.00e+00	7054.00
IUUC-Mmr-061092	Microcebus murinus	68.50	0.00e+00	3909.00
IUUC-Mdo-062610	Monodelphis domestica	71.25	0.00e+00	1713.00
IUUC-Mmu-063666	Mus musculus	70.13	0.00e+00	5331.00
IUUC-Mac-064935	Musa acuminata	33.16	8.00e-30	125.00
IUUC-Mpu-066366	Mustela putorius furo	70.65	0.00e+00	5349.00
IUUC-Mlu-068201	Myotis lucifugus	66.84	0.00e+00	3005.00
IUUC-Nle-069232	Nomascus leucogenys	67.67	0.00e+00	3887.00
IUUC-Opr-070625	Ochotona princeps	67.17	0.00e+00	933.00
IUUC-Ont-072401	Oreochromis niloticus	49.62	0.00e+00	1118.00
IUUC-Oan-072945	Ornithorhynchus anatinus	71.31	0.00e+00	3898.00
IUUC-Ocu-074920	Oryctolagus cuniculus	67.58	0.00e+00	3818.00
IUUC-Ola-086436	Oryzias latipes	48.33	0.00e+00	1384.00
IUUC-Oga-088637	Otolemur garnettii	68.38	0.00e+00	3326.00
IUUC-Oar-089363	Ovis aries	70.67	0.00e+00	4650.00
IUUC-Ptr-091527	Pan troglodytes	72.12	0.00e+00	5691.00
IUUC-Pan-092102	Papio anubis	70.07	0.00e+00	5439.00
IUUC-Pma-094252	Petromyzon marinus	45.14	2.00e-161	564.00
IUUC-Ppa-095221	Physcomitrella patens	33.19	2.00e-29	123.00
IUUC-Pfo-096288	Poecilia formosa	48.87	0.00e+00	1356.00
IUUC-Pab-098241	Pongo abelii	71.77	0.00e+00	3773.00
IUUC-Pop-099585	Populus trichocarpa	31.94	3.00e-27	116.00
IUUC-Pca-100103	Procavia capensis	90.34	0.00e+00	1346.00
IUUC-Ppe-101920	Prunus persica	32.14	2.00e-26	114.00
IUUC-Pva-102238	Pteropus vampyrus	65.20	0.00e+00	2029.00
IUUC-Rno-105660	Rattus norvegicus	72.07	0.00e+00	821.00
IUUC-Sha-106550	Sarcophilus harrisii	68.96	0.00e+00	3962.00
IUUC-Sar-113183	Sorex araneus	85.40	2.00e-150	528.00
IUUC-Sbi-113816	Sorghum bicolor	36.63	1.00e-12	68.60
IUUC-Ssc-115678	Sus scrofa	74.03	0.00e+00	885.00
IUUC-Tru-118037	Takifugu rubripes	48.81	0.00e+00	1533.00
IUUC-Tsy-118932	Tarsius syrichta	71.81	0.00e+00	4187.00
IUUC-Tni-119970	Tetraodon nigroviridis	54.23	0.00e+00	1298.00
IUUC-Tca-121624	Theobroma cacao	32.46	6.00e-27	115.00
IUUC-Tbe-127625	Tupaia belangeri	67.07	1.00e-99	359.00
IUUC-Ttr-129051	Tursiops truncatus	69.17	0.00e+00	5003.00
IUUC-Vpa-130236	Vicugna pacos	63.51	0.00e+00	1371.00
IUUC-Xtr-132455	Xenopus tropicalis	52.53	0.00e+00	928.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence