iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
circBase
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.10e-07	30.2	122	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw................pglknssskefrCPlCr 46
           C+iCl +   + +v+ C H++h+ C++++                +++k +  +++ CP+Cr
   Q: 122  CLICLASS--PIIVTACDHFMHFACFNRYltecltglrqeiqdaqKHMKEQVETNIFCPVCR 181
           ****9999..788999*********************99999999999999999999****8 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MESADGEIEA LCSIWDGVHV ESKLEASRRY LKHKIKSLED ESTSASVLIE MTVSEGYPAV 60
SPTVTLSNPR GIGEPEFREL QRQIQEIIEQ NSDEMPIICQ IFQHCSDFLT ENQHQNMDCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAATGGAG TCTGCAGACG GTGAAATTGA AGCCCTATGC AGTATTTGGG ATGGAGTCCA 60
CGTGGAGTCC AAATTAGAAG CTTCTCGGCG ATATTTAAAG CATAAAATTA AATCATTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50908--RWD
PS50089--ZF_RING_2

Pfam

PF05773--RWD

SMART

SM00184--RING
SM00591--RWD

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

KEGG

cel:CELE_Y53G8AR.5

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001954	Ailuropoda melanoleuca	23.74	7.00e-06	43.90
IUUC-Apl-003293	Anas platyrhynchos	22.78	1.00e-13	70.10
IUUC-Aca-005092	Anolis carolinensis	24.47	4.00e-13	68.20
IUUC-Ame-011754	Astyanax mexicanus	29.63	7.00e-15	73.90
IUUC-Bta-012592	Bos taurus	23.01	2.00e-11	62.40
IUUC-Cja-018930	Callithrix jacchus	21.43	3.00e-12	64.70
IUUC-Cfa-020156	Canis familiaris	22.50	2.00e-10	58.90
IUUC-Cpo-021290	Cavia porcellus	23.75	1.00e-11	63.20
IUUC-Csa-023214	Chlorocebus sabaeus	24.69	2.00e-13	69.30
IUUC-Csv-026360	Ciona savignyi	24.36	9.00e-12	63.50
IUUC-Dre-028670	Danio rerio	27.68	1.00e-09	57.00
IUUC-Dno-029970	Dasypus novemcinctus	23.33	8.00e-11	60.50
IUUC-Dor-030152	Dipodomys ordii	21.05	3.00e-07	48.10
IUUC-Dme-031914	Drosophila melanogaster	21.59	4.00e-12	64.30
IUUC-Ete-033105	Echinops telfairi	22.62	6.00e-12	64.30
IUUC-Eca-033800	Equus caballus	23.33	4.00e-12	64.70
IUUC-Fca-035644	Felis catus	24.27	1.00e-13	69.70
IUUC-Fal-037121	Ficedula albicollis	22.36	7.00e-14	70.90
IUUC-Gmo-039444	Gadus morhua	27.94	2.00e-13	68.90
IUUC-Gga-041221	Gallus gallus	24.86	9.00e-09	53.10
IUUC-Gac-042354	Gasterosteus aculeatus	28.44	3.00e-19	88.60
IUUC-Ggo-044879	Gorilla gorilla	23.65	2.00e-12	65.50
IUUC-Hsa-045739	Homo sapiens	23.65	2.00e-12	65.50
IUUC-Lch-050277	Latimeria chalumnae	26.03	2.00e-13	69.30
IUUC-Laf-053559	Loxodonta africana	23.95	3.00e-14	72.00
IUUC-Mcc-055367	Macaca mulatta	23.03	4.00e-09	54.70
IUUC-Meu-056730	Macropus eugenii	21.19	1.00e-05	43.50
IUUC-Mga-060090	Meleagris gallopavo	25.43	3.00e-09	55.10
IUUC-Mmr-060618	Microcebus murinus	24.07	2.00e-13	69.30
IUUC-Mdo-063084	Monodelphis domestica	23.23	5.00e-08	51.20
IUUC-Mmu-063854	Mus musculus	23.83	1.00e-11	62.80
IUUC-Mpu-066419	Mustela putorius furo	22.50	3.00e-11	61.60
IUUC-Mlu-067289	Myotis lucifugus	21.79	5.00e-07	47.80
IUUC-Nle-069090	Nomascus leucogenys	23.65	3.00e-12	65.10
IUUC-Opr-070601	Ochotona princeps	22.88	3.00e-15	74.70
IUUC-Ont-072434	Oreochromis niloticus	25.75	1.00e-16	80.10
IUUC-Ocu-074855	Oryctolagus cuniculus	21.85	5.00e-13	67.80
IUUC-Ola-087231	Oryzias latipes	25.13	4.00e-11	60.10
IUUC-Oga-088963	Otolemur garnettii	22.18	2.00e-13	68.90
IUUC-Oar-089292	Ovis aries	23.65	3.00e-12	65.10
IUUC-Ptr-091214	Pan troglodytes	24.28	2.00e-12	65.90
IUUC-Pan-092823	Papio anubis	24.07	3.00e-13	68.20
IUUC-Pfo-096406	Poecilia formosa	26.64	5.00e-16	77.40
IUUC-Pab-098212	Pongo abelii	24.07	4.00e-13	68.20
IUUC-Pca-100897	Procavia capensis	21.67	6.00e-09	54.30
IUUC-Pva-102899	Pteropus vampyrus	22.92	4.00e-12	64.70
IUUC-Rno-105369	Rattus norvegicus	24.53	3.00e-13	68.20
IUUC-Sha-107344	Sarcophilus harrisii	23.23	3.00e-08	51.60
IUUC-Smo-109636	Selaginella moellendorffii	26.96	6.00e-05	38.90
IUUC-Sbi-114714	Sorghum bicolor	20.26	1.00e-05	42.70
IUUC-Ssc-115465	Sus scrofa	24.07	3.00e-11	62.00
IUUC-Tgu-117113	Taeniopygia guttata	22.36	1.00e-13	69.70
IUUC-Ttr-128244	Tursiops truncatus	22.18	2.00e-14	72.40
IUUC-Vpa-130354	Vicugna pacos	23.33	4.00e-11	61.20
IUUC-Xtr-132402	Xenopus tropicalis	26.81	3.00e-16	78.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence