iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-049073

Ensembl Protein ID

ENSSTOP00000010786.2

UniProt Accession

I3MIF0; I3MIF0_ICTTR

Genbank Protein ID

ENSSTOP00000010786

Protein Name

Importin subunit alpha

Genbank Nucleotide ID

AGTP01008085

Gene Name

KPNA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000012014.2	ENSSTOT00000012020.2	ENSSTOP00000010786.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/U-box	28.79	5.00e-04	35.00	IUUC-Ots-000046

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Functional Description
(View)

Functions in nuclear protein import.

Protein Sequence
(Fasta)

FIFSLLETMA SPGKDNYRMK SYKNNALNPE EMRRRREEEG IQLRKQKREQ QLFKRRNVEL 60
INEEAAMFDS LLMDSYVSST TGESVITREM VEMLFSDDSD LQLATTQKFR KLLSKEPSPP 120

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Nucleotide Sequence
(Fasta)

TTTATATTTT CCCTTCTAGA GACCATGGCG AGCCCAGGAA AAGACAATTA TCGAATGAAG 60
AGCTATAAGA ACAATGCCTT GAACCCCGAG GAAATGAGGC GAAGAAGAGA GGAAGAGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR032413--Arm_3
IPR000225--Armadillo
IPR002652--Importin-a_IBB
IPR024931--Importing_su_alpha

PROSITE

PS50176--ARM_REPEAT
PS51214--IBB

Pfam

PF00514--Arm
PF16186--Arm_3
PF01749--IBB

SMART

SM00185--ARM

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0005634--C:nucleus
GO:0008565--F:protein transporter activity
GO:0060135--P:maternal process involved in female pregnancy
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006606--P:protein import into nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000143	Aegilops tauschii	27.73	7.00e-07	49.30
IUUC-Acl-008113	Aspergillus clavatus	25.90	1.00e-11	64.70
IUUC-Ani-009476	Aspergillus nidulans	26.29	4.00e-12	65.90
IUUC-Bta-013555	Bos taurus	28.47	4.00e-04	40.80
IUUC-Cho-024666	Choloepus hoffmanni	44.64	2.00e-91	329.00
IUUC-Cme-027156	Cyanidioschyzon merolae	54.59	8.00e-117	414.00
IUUC-Ggr-039908	Gaeumannomyces graminis	26.79	6.00e-12	65.50
IUUC-Gac-041812	Gasterosteus aculeatus	25.96	2.00e-04	42.00
IUUC-Ggo-045030	Gorilla gorilla	28.47	3.00e-04	40.80
IUUC-Hvu-047783	Hordeum vulgare	27.73	7.00e-07	49.30
IUUC-Meu-056121	Macropus eugenii	29.20	1.00e-04	42.40
IUUC-Mpo-057354	Magnaporthe poae	26.79	7.00e-12	65.10
IUUC-Mvi-060440	Microbotryum violaceum	58.83	2.00e-159	555.00
IUUC-Mlu-067208	Myotis lucifugus	28.47	3.00e-04	40.80
IUUC-Oga-088587	Otolemur garnettii	28.47	1.00e-04	42.00
IUUC-Pno-095110	Phaeosphaeria nodorum	27.09	2.00e-12	66.60
IUUC-Ptt-103922	Puccinia triticina	27.17	6.00e-03	34.70
IUUC-Pte-104314	Pyrenophora teres	27.49	3.00e-12	66.60
IUUC-Sha-107173	Sarcophilus harrisii	29.20	3.00e-04	41.20
IUUC-Ssl-108596	Sclerotinia sclerotiorum	27.09	4.00e-13	69.30
IUUC-Sar-113307	Sorex araneus	28.47	4.00e-04	40.00
IUUC-Ssc-115521	Sus scrofa	96.33	0.00e+00	853.00
IUUC-Tru-118154	Takifugu rubripes	25.22	5.00e-06	47.00
IUUC-Tni-120112	Tetraodon nigroviridis	25.71	1.00e-04	42.40
IUUC-Tur-126573	Triticum urartu	27.73	6.00e-07	49.30
IUUC-Ttr-129113	Tursiops truncatus	99.44	0.00e+00	991.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence