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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105586
Ensembl Protein ID ENSRNOP00000070836.1
UniProt Accession A0A0G2JYY3; A0A0G2JYY3_RAT
Genbank Protein ID ENSRNOP00000070836
Protein Name Activated CDC42 kinase 1
Genbank Nucleotide ID AC136847
Gene Name Tnk2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000001769.7 ENSRNOT00000084768.1 ENSRNOP00000070836.1
ENSRNOG00000001769.7 ENSRNOT00000002411.7 ENSRNOP00000002411.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 97.82 0.00e+00 1842.00 IUUC-Mmu-063861
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NITRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAMC KRKSWMSKVF SGKRQEAEFP SHHSQSTFRK PSPTPGGLAG EGTLQSLTCL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105586|UBD,UBA|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTCCCCAGCG GGAGAGGGAT TCCAAGAGGG ACACAGAACC CGCAGGCGCA GACGACGAAG 60
GAGGTGGTAA TCTGCAAGCT GCCTTACTGG CATCGGGGTT GCTCTAGTGC CAAGAGGAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105586|UBD,UBA|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3
Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9
PRINTS

PR00109--TYRKINASE
SMART

SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002166 Ailuropoda melanoleuca 91.96 0.00e+00 1667.00
IUUC-Aca-004315 Anolis carolinensis 88.97 1.00e-73 268.00
IUUC-Ame-011350 Astyanax mexicanus 54.87 0.00e+00 1033.00
IUUC-Bta-012325 Bos taurus 92.51 0.00e+00 1729.00
IUUC-Cel-018130 Caenorhabditis elegans 36.67 2.00e-89 324.00
IUUC-Cja-019545 Callithrix jacchus 86.84 0.00e+00 1568.00
IUUC-Cfa-020706 Canis familiaris 92.90 0.00e+00 1744.00
IUUC-Cpo-022032 Cavia porcellus 89.94 0.00e+00 1690.00
IUUC-Csa-023936 Chlorocebus sabaeus 94.31 0.00e+00 1736.00
IUUC-Csv-026328 Ciona savignyi 59.24 1.00e-173 602.00
IUUC-Dre-028714 Danio rerio 63.86 0.00e+00 1215.00
IUUC-Dno-029525 Dasypus novemcinctus 92.23 0.00e+00 1730.00
IUUC-Dme-031778 Drosophila melanogaster 56.57 1.00e-144 508.00
IUUC-Ete-032225 Echinops telfairi 89.76 0.00e+00 850.00
IUUC-Fca-035664 Felis catus 92.90 0.00e+00 1790.00
IUUC-Gmo-039543 Gadus morhua 58.54 0.00e+00 922.00
IUUC-Gga-040241 Gallus gallus 67.63 0.00e+00 1302.00
IUUC-Gac-041457 Gasterosteus aculeatus 62.98 0.00e+00 1123.00
IUUC-Ggo-045333 Gorilla gorilla 91.75 0.00e+00 1705.00
IUUC-Hsa-046670 Homo sapiens 92.51 0.00e+00 1675.00
IUUC-Itr-048054 Ictidomys tridecemlineatus 94.59 0.00e+00 1788.00
IUUC-Lch-049670 Latimeria chalumnae 63.07 0.00e+00 1192.00
IUUC-Loc-052870 Lepisosteus oculatus 64.34 0.00e+00 1259.00
IUUC-Laf-053782 Loxodonta africana 91.27 0.00e+00 1686.00
IUUC-Mcc-055874 Macaca mulatta 94.31 0.00e+00 1724.00
IUUC-Mga-059717 Meleagris gallopavo 70.60 0.00e+00 1368.00
IUUC-Mdo-062270 Monodelphis domestica 85.63 0.00e+00 1614.00
IUUC-Mmu-063861 Mus musculus 97.82 0.00e+00 1873.00
IUUC-Mpu-066127 Mustela putorius furo 95.64 0.00e+00 1367.00
IUUC-Mlu-067937 Myotis lucifugus 90.27 0.00e+00 1330.00
IUUC-Nle-069298 Nomascus leucogenys 91.36 0.00e+00 1392.00
IUUC-Ont-072437 Oreochromis niloticus 58.09 0.00e+00 1155.00
IUUC-Oan-073708 Ornithorhynchus anatinus 75.00 3.00e-115 409.00
IUUC-Ola-087023 Oryzias latipes 62.00 0.00e+00 1151.00
IUUC-Pan-091857 Papio anubis 91.15 3.00e-93 334.00
IUUC-Psi-093401 Pelodiscus sinensis 54.95 9.00e-149 520.00
IUUC-Pfo-097455 Poecilia formosa 59.62 0.00e+00 1192.00
IUUC-Sha-106868 Sarcophilus harrisii 88.09 0.00e+00 1291.00
IUUC-Ssc-116250 Sus scrofa 91.86 0.00e+00 1659.00
IUUC-Tgu-116592 Taeniopygia guttata 70.14 0.00e+00 1299.00
IUUC-Tru-117852 Takifugu rubripes 70.25 1.00e-180 627.00
IUUC-Tsy-119087 Tarsius syrichta 98.51 1.00e-158 554.00
IUUC-Tni-120826 Tetraodon nigroviridis 63.32 0.00e+00 1223.00
IUUC-Xtr-132069 Xenopus tropicalis 65.41 0.00e+00 1184.00
Created Date 25-Jun-2017

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