iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070177

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01070440

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000008016.1	ENSNLET00000010258.1	ENSNLEP00000009787.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.80e-09	35.7	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+ +Cl + w     ++    +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGSCLnETW----AVQGAPYLCPQCR 54
           ********99.****************9**....8999999*****8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAELCPLAEE LSCSICLEPF KEPVTTPCGH NFCGSCLNET WAVQGAPYLC PQCRAAYQAR 60
PQLHKNTVLC NVVEQFLQAD LARETPADGW TPPARASAPS PGAPVACDHC LKEAAVKTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGTGCGG GTGCAGCAGT CGCGTCCCGA CCCCTGGGAG CGCCATGGCG GAGCTGTGCC 60
CGCTGGCCGA GGAGCTGTCG TGCTCCATCT GCCTGGAGCC CTTCAAGGAA CCGGTCACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell
GO:0043627--P:response to estrogen

KEGG

nle:100599729

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	77.22	0.00e+00	968.00
IUUC-Apl-004101	Anas platyrhynchos	49.45	2.00e-168	585.00
IUUC-Aca-005025	Anolis carolinensis	49.29	9.00e-174	603.00
IUUC-Ame-011586	Astyanax mexicanus	25.84	1.00e-57	217.00
IUUC-Bta-012735	Bos taurus	74.49	0.00e+00	951.00
IUUC-Bci-013931	Botrytis cinerea	39.53	3.00e-08	54.30
IUUC-Cja-019996	Callithrix jacchus	83.30	0.00e+00	731.00
IUUC-Cfa-020466	Canis familiaris	76.10	0.00e+00	968.00
IUUC-Cpo-021737	Cavia porcellus	70.46	0.00e+00	882.00
IUUC-Csa-023217	Chlorocebus sabaeus	94.44	0.00e+00	1165.00
IUUC-Cho-024346	Choloepus hoffmanni	50.33	2.00e-70	259.00
IUUC-Dre-028336	Danio rerio	31.56	2.00e-61	229.00
IUUC-Dno-030082	Dasypus novemcinctus	72.91	0.00e+00	940.00
IUUC-Dor-030335	Dipodomys ordii	53.44	5.00e-130	457.00
IUUC-Dse-031151	Dothistroma septosporum	36.36	7.00e-07	49.30
IUUC-Ete-032923	Echinops telfairi	69.22	0.00e+00	790.00
IUUC-Eca-033411	Equus caballus	74.73	0.00e+00	947.00
IUUC-Eeu-034656	Erinaceus europaeus	72.85	1.00e-161	562.00
IUUC-Fca-035371	Felis catus	76.73	0.00e+00	978.00
IUUC-Fal-037008	Ficedula albicollis	46.47	5.00e-159	554.00
IUUC-Gmo-038668	Gadus morhua	33.92	2.00e-103	369.00
IUUC-Gga-040608	Gallus gallus	48.01	4.00e-162	564.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.33	5.00e-113	401.00
IUUC-Ggo-044518	Gorilla gorilla	95.56	0.00e+00	1145.00
IUUC-Hsa-045828	Homo sapiens	96.51	0.00e+00	1185.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	58.19	0.00e+00	699.00
IUUC-Lch-050478	Latimeria chalumnae	38.01	2.00e-127	449.00
IUUC-Loc-052864	Lepisosteus oculatus	35.95	1.00e-111	397.00
IUUC-Lma-053260	Leptosphaeria maculans	36.90	4.00e-09	57.00
IUUC-Laf-054325	Loxodonta africana	77.69	3.00e-170	590.00
IUUC-Mcc-054920	Macaca mulatta	95.08	0.00e+00	1170.00
IUUC-Meu-056367	Macropus eugenii	73.41	9.00e-75	274.00
IUUC-Mga-059975	Meleagris gallopavo	49.13	2.00e-163	568.00
IUUC-Mmr-060748	Microcebus murinus	81.33	0.00e+00	997.00
IUUC-Mdo-062904	Monodelphis domestica	58.48	0.00e+00	708.00
IUUC-Mmu-063891	Mus musculus	72.60	0.00e+00	943.00
IUUC-Mpu-066473	Mustela putorius furo	76.40	0.00e+00	993.00
IUUC-Mlu-068185	Myotis lucifugus	77.85	0.00e+00	955.00
IUUC-Opr-070558	Ochotona princeps	61.95	1.00e-152	532.00
IUUC-Ont-071368	Oreochromis niloticus	48.35	3.00e-53	202.00
IUUC-Ocu-074461	Oryctolagus cuniculus	56.06	0.00e+00	648.00
IUUC-Ogu-078203	Oryza glumaepatula	47.06	3.00e-10	59.30
IUUC-Opu-083547	Oryza punctata	48.53	2.00e-10	60.10
IUUC-Ola-087394	Oryzias latipes	29.55	2.00e-62	233.00
IUUC-Oga-088937	Otolemur garnettii	74.25	0.00e+00	946.00
IUUC-Oar-089781	Ovis aries	74.66	0.00e+00	644.00
IUUC-Ptr-090771	Pan troglodytes	96.35	0.00e+00	1160.00
IUUC-Pan-092830	Papio anubis	94.60	0.00e+00	1166.00
IUUC-Psi-093664	Pelodiscus sinensis	52.31	1.00e-179	622.00
IUUC-Pma-094147	Petromyzon marinus	27.96	9.00e-63	234.00
IUUC-Pfo-096528	Poecilia formosa	35.07	3.00e-111	395.00
IUUC-Pab-097588	Pongo abelii	96.19	0.00e+00	1169.00
IUUC-Pca-100890	Procavia capensis	74.37	0.00e+00	885.00
IUUC-Pva-102314	Pteropus vampyrus	80.88	0.00e+00	966.00
IUUC-Pgr-103377	Puccinia graminis	39.29	2.00e-06	47.40
IUUC-Ptt-103758	Puccinia triticina	39.29	6.00e-06	44.70
IUUC-Rno-105234	Rattus norvegicus	74.64	6.00e-156	544.00
IUUC-Sce-106362	Saccharomyces cerevisiae	44.93	4.00e-09	55.50
IUUC-Sha-106807	Sarcophilus harrisii	54.61	0.00e+00	657.00
IUUC-Ssl-108645	Sclerotinia sclerotiorum	39.53	4.00e-08	53.90
IUUC-Sar-113283	Sorex araneus	59.25	4.00e-136	477.00
IUUC-Ssc-115878	Sus scrofa	80.43	2.00e-107	381.00
IUUC-Tgu-117026	Taeniopygia guttata	45.79	2.00e-127	449.00
IUUC-Tru-118624	Takifugu rubripes	26.24	6.00e-60	225.00
IUUC-Tni-120550	Tetraodon nigroviridis	26.93	1.00e-65	244.00
IUUC-Tbe-127580	Tupaia belangeri	71.99	2.00e-155	541.00
IUUC-Ttr-128648	Tursiops truncatus	74.48	0.00e+00	658.00
IUUC-Vpa-130254	Vicugna pacos	89.71	3.00e-97	348.00
IUUC-Xtr-132892	Xenopus tropicalis	42.73	2.00e-74	272.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence