iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005185

UUCD1 version

UUC-AnC-00372

Ensembl Protein ID

ENSACAP00000008950.2

UniProt Accession

H9GEV1; H9GEV1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009107.2	ENSACAT00000009141.2	ENSACAP00000008950.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	28.97	8.00e-11	65.50	IUUC-Ath-007305
E3 adaptor/Cullin RING/SCF/F-box	29.73	6.00e-28	121.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	62.21	1.00e-139	494.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	57.31	1.00e-122	437.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

ICRRLLQEIP DSGSNVNTDF MWGWHSSKTS ELLSVTGVSV LKDKLGNENT PQELLMCVSP 60
PPKRQKVKEP EFVIVRRPRR LLELAAGVSW DALPDELLLG IFSYLSLTDL LKVSLVCQRW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTGTAGGA GACTTCTCCA GGAAATTCCA GATTCGGGCA GCAATGTCAA CACGGATTTC 60
ATGTGGGGAT GGCATTCCAG CAAGACTTCA GAGCTGCTGT CCGTCACGGG AGTCTCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	62.91	5.00e-138	483.00
IUUC-Apl-003453	Anas platyrhynchos	68.73	7.00e-125	439.00
IUUC-Ath-007305	Arabidopsis thaliana	28.97	9.00e-12	65.10
IUUC-Ame-010665	Astyanax mexicanus	48.56	2.00e-100	359.00
IUUC-Bta-013450	Bos taurus	61.74	2.00e-142	498.00
IUUC-Bdi-014782	Brachypodium distachyon	26.74	8.00e-11	62.00
IUUC-Bol-016359	Brassica oleracea	27.04	1.00e-11	64.70
IUUC-Bra-016717	Brassica rapa	26.16	1.00e-10	59.70
IUUC-Cel-018410	Caenorhabditis elegans	27.58	2.00e-25	109.00
IUUC-Cja-019834	Callithrix jacchus	61.27	1.00e-139	489.00
IUUC-Cfa-020401	Canis familiaris	62.68	3.00e-143	501.00
IUUC-Cpo-022183	Cavia porcellus	62.59	8.00e-141	493.00
IUUC-Csa-023418	Chlorocebus sabaeus	63.15	6.00e-143	500.00
IUUC-Cho-024412	Choloepus hoffmanni	60.34	7.00e-109	387.00
IUUC-Cin-025248	Ciona intestinalis	29.22	1.00e-39	157.00
IUUC-Csv-026189	Ciona savignyi	31.00	7.00e-36	144.00
IUUC-Dre-028032	Danio rerio	51.84	2.00e-113	402.00
IUUC-Dno-029222	Dasypus novemcinctus	61.74	8.00e-142	496.00
IUUC-Dor-030505	Dipodomys ordii	59.22	8.00e-103	367.00
IUUC-Dme-031972	Drosophila melanogaster	34.46	6.00e-51	195.00
IUUC-Ete-032234	Echinops telfairi	57.62	3.00e-71	261.00
IUUC-Eca-033944	Equus caballus	63.15	6.00e-144	503.00
IUUC-Eeu-035008	Erinaceus europaeus	62.41	3.00e-81	294.00
IUUC-Fca-035412	Felis catus	63.15	3.00e-144	504.00
IUUC-Fal-037337	Ficedula albicollis	66.04	1.00e-145	509.00
IUUC-Gmo-038934	Gadus morhua	44.92	1.00e-46	180.00
IUUC-Gga-041152	Gallus gallus	72.14	4.00e-169	587.00
IUUC-Gac-041819	Gasterosteus aculeatus	45.08	2.00e-81	295.00
IUUC-Ggo-045479	Gorilla gorilla	62.01	2.00e-115	408.00
IUUC-Hsa-046512	Homo sapiens	62.21	4.00e-141	494.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	60.58	2.00e-133	468.00
IUUC-Lch-050115	Latimeria chalumnae	57.38	7.00e-133	466.00
IUUC-Lpe-051259	Leersia perrieri	26.30	8.00e-10	58.50
IUUC-Loc-052554	Lepisosteus oculatus	49.41	1.00e-105	376.00
IUUC-Laf-053563	Loxodonta africana	61.45	1.00e-135	476.00
IUUC-Mcc-055143	Macaca mulatta	63.08	2.00e-144	505.00
IUUC-Meu-056593	Macropus eugenii	52.82	7.00e-85	307.00
IUUC-Mga-060084	Meleagris gallopavo	68.80	1.00e-100	358.00
IUUC-Mmr-060660	Microcebus murinus	63.29	9.00e-145	506.00
IUUC-Mdo-062363	Monodelphis domestica	60.99	3.00e-131	461.00
IUUC-Mmu-063287	Mus musculus	58.69	3.00e-134	471.00
IUUC-Mpu-065791	Mustela putorius furo	63.15	2.00e-144	505.00
IUUC-Mlu-067714	Myotis lucifugus	59.86	9.00e-135	473.00
IUUC-Nle-069823	Nomascus leucogenys	62.68	3.00e-142	498.00
IUUC-Opr-071046	Ochotona princeps	61.90	3.00e-50	192.00
IUUC-Ont-071820	Oreochromis niloticus	44.85	1.00e-66	247.00
IUUC-Ocu-074868	Oryctolagus cuniculus	61.74	3.00e-141	494.00
IUUC-Obr-076639	Oryza brachyantha	25.00	1.00e-07	51.20
IUUC-Opu-083852	Oryza punctata	25.81	6.00e-09	55.80
IUUC-Ola-086608	Oryzias latipes	46.15	2.00e-76	279.00
IUUC-Oga-089044	Otolemur garnettii	63.62	2.00e-145	508.00
IUUC-Oar-089650	Ovis aries	61.74	1.00e-142	499.00
IUUC-Ptr-090743	Pan troglodytes	62.21	5.00e-141	493.00
IUUC-Pan-092501	Papio anubis	63.15	1.00e-143	502.00
IUUC-Psi-094032	Pelodiscus sinensis	67.85	2.00e-164	571.00
IUUC-Pfo-097279	Poecilia formosa	44.33	1.00e-62	233.00
IUUC-Pab-097821	Pongo abelii	62.85	1.00e-116	412.00
IUUC-Pca-100100	Procavia capensis	62.29	9.00e-110	389.00
IUUC-Pva-103181	Pteropus vampyrus	58.95	1.00e-109	389.00
IUUC-Rno-105091	Rattus norvegicus	59.39	1.00e-134	472.00
IUUC-Sha-107226	Sarcophilus harrisii	64.13	1.00e-142	498.00
IUUC-Smo-109321	Selaginella moellendorffii	27.51	7.00e-12	66.20
IUUC-Sit-110450	Setaria italica	25.93	5.00e-09	55.80
IUUC-Sbi-114639	Sorghum bicolor	26.94	2.00e-10	60.80
IUUC-Ssc-115665	Sus scrofa	62.91	2.00e-144	505.00
IUUC-Tgu-116982	Taeniopygia guttata	63.55	2.00e-138	485.00
IUUC-Tru-118276	Takifugu rubripes	46.75	1.00e-76	279.00
IUUC-Tsy-119074	Tarsius syrichta	63.41	4.00e-119	421.00
IUUC-Tni-120702	Tetraodon nigroviridis	42.61	1.00e-45	176.00
IUUC-Tbe-127990	Tupaia belangeri	60.86	7.00e-95	340.00
IUUC-Ttr-128661	Tursiops truncatus	56.39	2.00e-74	273.00
IUUC-Xtr-132166	Xenopus tropicalis	57.07	6.00e-124	437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence