iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020710

Ensembl Protein ID

ENSCAFP00000012352.3

UniProt Accession

F6XB90; F6XB90_CANLF

Genbank Protein ID

ENSCAFP00000012352

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010965

Gene Name

AUP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000008402.3	ENSCAFT00000013349.3	ENSCAFP00000012352.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/CUE	8.60e-10	38.7	297	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/CUE

   S: 2    letaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           l+ +++++ke++P+++  viq++L a+tg+++ +++nLLeg+
   Q: 297  LAALAQRVKEVLPHVPLGVIQRDL-ARTGCVDLTITNLLEGA 337
           67899*******************.***************96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDPSPALGPE RLFDSHRLPG DGFLLLALLL YAPVGFCLLV LRLFLGIHVF LVSCALPDSV 60
LRRFVVRTMC AVLGLVARQE NSGLRDHRVR VLISNHVTPF DHNIVNLLTS CSTPLLNSPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCCTT CCCCGGCGCT GGGGCCGGAG CGGCTCTTCG ACTCTCACCG GTAAGAGCCC 60
TGGCGGGAAG AGGCCGGCTC CCGCGTGCAC TCGGCCTCCG GCGCCCGATC ACCCCGCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE

PROSITE

PS51140--CUE

Pfam

PF02845--CUE

SMART

SM00546--CUE

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0043130--F:ubiquitin binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002330	Ailuropoda melanoleuca	98.28	5.00e-180	624.00
IUUC-Apl-003946	Anas platyrhynchos	57.54	2.00e-102	365.00
IUUC-Aca-004676	Anolis carolinensis	53.78	7.00e-26	109.00
IUUC-Ago-007976	Ashbya gossypii	36.36	5.00e-01	27.30
IUUC-Acl-008157	Aspergillus clavatus	32.84	1.20e-01	30.00
IUUC-Bta-012397	Bos taurus	95.85	0.00e+00	724.00
IUUC-Bdi-014890	Brachypodium distachyon	31.73	5.00e-04	39.30
IUUC-Cel-018644	Caenorhabditis elegans	34.46	2.00e-43	170.00
IUUC-Cja-018775	Callithrix jacchus	95.99	2.00e-145	509.00
IUUC-Cpo-022111	Cavia porcellus	96.34	0.00e+00	722.00
IUUC-Csa-023411	Chlorocebus sabaeus	97.02	0.00e+00	709.00
IUUC-Cin-025458	Ciona intestinalis	40.38	2.00e-14	70.10
IUUC-Dre-027938	Danio rerio	53.86	1.00e-117	416.00
IUUC-Dno-028873	Dasypus novemcinctus	94.88	0.00e+00	706.00
IUUC-Dor-030537	Dipodomys ordii	82.39	0.00e+00	626.00
IUUC-Ete-032422	Echinops telfairi	69.28	2.00e-145	508.00
IUUC-Eca-033757	Equus caballus	96.59	0.00e+00	719.00
IUUC-Eeu-034556	Erinaceus europaeus	76.81	0.00e+00	633.00
IUUC-Fca-035438	Felis catus	97.56	0.00e+00	726.00
IUUC-Fal-036911	Ficedula albicollis	54.67	3.00e-95	341.00
IUUC-Gmo-039147	Gadus morhua	51.21	2.00e-104	372.00
IUUC-Gga-041239	Gallus gallus	57.83	1.00e-114	406.00
IUUC-Gac-041814	Gasterosteus aculeatus	51.57	1.00e-108	386.00
IUUC-Ggo-044745	Gorilla gorilla	95.99	4.00e-146	511.00
IUUC-Hsa-046167	Homo sapiens	96.28	0.00e+00	705.00
IUUC-Itr-048661	Ictidomys tridecemlineatus	97.13	0.00e+00	670.00
IUUC-Lch-050576	Latimeria chalumnae	52.64	4.00e-101	361.00
IUUC-Lpe-051312	Leersia perrieri	33.01	5.00e-04	39.30
IUUC-Loc-052028	Lepisosteus oculatus	54.63	1.00e-116	412.00
IUUC-Laf-053886	Loxodonta africana	94.01	0.00e+00	645.00
IUUC-Mcc-055399	Macaca mulatta	91.32	0.00e+00	640.00
IUUC-Meu-056355	Macropus eugenii	64.77	6.00e-123	434.00
IUUC-Mga-060065	Meleagris gallopavo	53.76	2.00e-94	338.00
IUUC-Mmu-064080	Mus musculus	91.74	2.00e-156	545.00
IUUC-Mpu-066233	Mustela putorius furo	98.78	0.00e+00	738.00
IUUC-Mlu-067489	Myotis lucifugus	96.83	0.00e+00	719.00
IUUC-Nle-070040	Nomascus leucogenys	96.32	1.00e-147	516.00
IUUC-Ont-071616	Oreochromis niloticus	52.23	2.00e-108	385.00
IUUC-Ocu-074618	Oryctolagus cuniculus	95.26	0.00e+00	705.00
IUUC-Obr-076127	Oryza brachyantha	35.92	2.00e-05	43.90
IUUC-Ogl-077799	Oryza glaberrima	35.24	1.00e-02	35.00
IUUC-Ome-081941	Oryza meridionalis	43.59	2.00e-04	40.40
IUUC-Ola-086583	Oryzias latipes	51.85	5.00e-72	265.00
IUUC-Oga-089100	Otolemur garnettii	95.12	0.00e+00	714.00
IUUC-Oar-089813	Ovis aries	95.61	0.00e+00	722.00
IUUC-Ptr-091436	Pan troglodytes	96.53	0.00e+00	705.00
IUUC-Pan-092755	Papio anubis	96.77	0.00e+00	709.00
IUUC-Psi-093736	Pelodiscus sinensis	68.28	3.00e-54	204.00
IUUC-Pma-094429	Petromyzon marinus	50.13	2.00e-90	326.00
IUUC-Pfo-097015	Poecilia formosa	50.12	1.00e-103	369.00
IUUC-Pab-098382	Pongo abelii	96.77	0.00e+00	708.00
IUUC-Pca-100900	Procavia capensis	92.04	1.00e-88	320.00
IUUC-Pva-103248	Pteropus vampyrus	69.54	2.00e-145	508.00
IUUC-Rno-105755	Rattus norvegicus	92.84	1.00e-171	595.00
IUUC-Sha-107434	Sarcophilus harrisii	78.40	1.00e-107	382.00
IUUC-Stu-112774	Solanum tuberosum	28.04	9.00e-03	35.00
IUUC-Sar-113104	Sorex araneus	74.41	3.00e-101	361.00
IUUC-Sre-115215	Sporisorium reilianum	31.88	2.70e-02	32.00
IUUC-Ssc-116047	Sus scrofa	92.69	1.00e-173	602.00
IUUC-Tgu-117436	Taeniopygia guttata	56.96	2.00e-111	395.00
IUUC-Tru-118227	Takifugu rubripes	48.81	1.00e-103	370.00
IUUC-Tni-120873	Tetraodon nigroviridis	49.64	1.00e-104	373.00
IUUC-Ttr-128895	Tursiops truncatus	79.15	0.00e+00	638.00
IUUC-Xtr-131917	Xenopus tropicalis	57.34	6.00e-60	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence