iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-97	327.2	355	927

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflafl 99
           +Gl+NlgNtC+m S+ QcLsn+p+lre++l   +++++ne+np +++g+l++++ +l++ +w+++  +++pr+++++++++a++f+gy+qqDa+E++a++
   Q: 355  CGLSNLGNTCFMASAFQCLSNMPPLREYFLAnTYQNDINEDNPLGTHGHLAMAVGELMKGMWSGDYASINPRKFKSIIGQFAPRFNGYSQQDAHELMAYV 454
           7*****************************9899****************************************************************** PP
   S: 100  ldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke......... 185
           ld+l+e+l++ k+kp+ e ++ed + l++      ++e  k++n+s+i+d+++gqlks+++c+ c+++s +++pf +lslp+p ke+  k+         
   Q: 455  LDGLHEDLNRIKKKPYIEDSDEDAK-LPEAeyaakSWEVYKMRNDSIIVDTLHGQLKSTLICPVCEKISIKFDPFGYLSLPLPPKEQIVKQtvivmfltr 553
           ****************999988854.444448888************************************************999887779******** PP
   S: 186  .................................................................................................... 185
                                                                                                               
   Q: 554  kwakfslgitdtttveeaerlmldklqpeqqhhfvffhvpsqyhdditmmrpgdrvrmpgrevyvaevehdlqvkgtrlfvaynriklvrsaslpmiysl 653
           **************************************************************************************************** PP
   S: 186  .................................................................................................... 185
                                                                                                               
   Q: 654  ptgypltrgflndhvfsttkhffinpkavaelgggnsndddsmsgsnsaderepyklfvgppgstaslpipptddpipfpdenshdiysnflqivfqwkd 753
           **************************************************************************************************** PP
   S: 186  .........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.L 259
                                     lq+ L+ ft++e+l +++ +yc++ckk+ +a+k+l l+klPe+LilhLkRf++++  +srek++ +v +p + L
   Q: 754  lkifnqykgnelieremtvstrrkvLLQETLDWFTTKEQLGEQDSWYCPQCKKHERATKQLALWKLPEILILHLKRFQYTK--WSREKLTWEVVIPVRgL 851
           *****************************************************************************8855..***************** PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev.ke.eevleetgstaYvlfYkrr 338
           dl+  +++p+ +   k +Y+Liav  H+Gsls+GHY+a+ +n++++ W+ f+Ds+ +++ +  e  ++   s++Y+l+Y+rr
   Q: 852  DLTDKVANPNHE---KAIYDLIAVSRHYGSLSGGHYTAIGYNDREQkWFDFNDSSANPTyPPaEPYES---SDPYILVYRRR 927
           *******99976...79*************************77767**********99433144555...9*******986 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MPTPEDVPMD ENDAGRVAEG SQDESKTPSR EVLKKLLNEV EMAEMEENEM WYLISQKWWN 60
SLIKAVRDGF VDDVGPIDNS QISECRNGSF FLKQRLAEQV DYTPVPEILF KRLERFYHID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGATTGC CTACACTCAA ATATACGTAA CGATGCCAAC TCCCGAGGAT GTTCCCATGG 60
ATGAAAATGA CGCAGGAAGA GTAGCAGAAG GCTCCCAGGA TGAATCTGTA CTGAATCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cel:CELE_H34C03.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	49.04	6.00e-58	218.00
IUUC-Atr-002955	Amborella trichopoda	52.94	1.00e-55	210.00
IUUC-Apl-003249	Anas platyrhynchos	59.39	1.00e-69	256.00
IUUC-Aca-004261	Anolis carolinensis	59.39	1.00e-69	256.00
IUUC-Aly-006315	Arabidopsis lyrata	54.76	6.00e-55	207.00
IUUC-Ath-007288	Arabidopsis thaliana	35.51	1.00e-95	342.00
IUUC-Ago-007911	Ashbya gossypii	46.94	1.00e-51	197.00
IUUC-Acl-008284	Aspergillus clavatus	41.84	8.00e-45	175.00
IUUC-Afl-008507	Aspergillus flavus	43.10	2.00e-45	176.00
IUUC-Afu-008878	Aspergillus fumigatus	44.12	3.00e-47	183.00
IUUC-Ani-009479	Aspergillus nidulans	50.00	6.00e-45	175.00
IUUC-Ang-009562	Aspergillus niger	48.42	2.00e-44	173.00
IUUC-Aor-009949	Aspergillus oryzae	43.10	2.00e-45	177.00
IUUC-Ate-010323	Aspergillus terreus	40.76	3.00e-44	173.00
IUUC-Ame-010757	Astyanax mexicanus	60.71	2.00e-72	265.00
IUUC-Bgr-012277	Blumeria graminis	46.22	8.00e-53	202.00
IUUC-Bta-013128	Bos taurus	59.90	2.00e-70	259.00
IUUC-Bci-013993	Botrytis cinerea	47.40	3.00e-51	196.00
IUUC-Bdi-014013	Brachypodium distachyon	35.94	3.00e-94	338.00
IUUC-Bol-015244	Brassica oleracea	37.28	2.00e-97	348.00
IUUC-Bra-016885	Brassica rapa	36.82	1.00e-96	346.00
IUUC-Cja-019222	Callithrix jacchus	58.88	3.00e-69	255.00
IUUC-Cpo-022071	Cavia porcellus	58.88	3.00e-69	255.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	54.89	9.00e-59	219.00
IUUC-Csv-026109	Ciona savignyi	57.07	8.00e-65	240.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	41.13	2.00e-50	194.00
IUUC-Cne-026852	Cryptococcus neoformans	53.06	3.00e-56	213.00
IUUC-Cme-027338	Cyanidioschyzon merolae	51.02	8.00e-56	210.00
IUUC-Dor-031038	Dipodomys ordii	56.45	3.00e-63	235.00
IUUC-Dse-031432	Dothistroma septosporum	42.08	3.00e-48	186.00
IUUC-Ete-032970	Echinops telfairi	55.91	3.00e-61	229.00
IUUC-Eca-034012	Equus caballus	56.99	4.00e-63	235.00
IUUC-Eeu-034488	Erinaceus europaeus	58.88	3.00e-69	255.00
IUUC-Fal-037634	Ficedula albicollis	54.37	7.00e-66	244.00
IUUC-Fox-037986	Fusarium oxysporum	48.15	3.00e-50	192.00
IUUC-Fso-038291	Fusarium solani	42.54	2.00e-51	197.00
IUUC-Gmo-038680	Gadus morhua	57.79	5.00e-70	257.00
IUUC-Ggr-039740	Gaeumannomyces graminis	51.03	9.00e-53	201.00
IUUC-Gga-041146	Gallus gallus	59.41	4.00e-70	258.00
IUUC-Gac-041679	Gasterosteus aculeatus	56.72	2.00e-69	256.00
IUUC-Gma-043077	Glycine max	56.06	7.00e-64	237.00
IUUC-Hvu-047108	Hordeum vulgare	49.27	1.00e-57	216.00
IUUC-Kpa-049332	Komagataella pastoris	45.08	3.00e-51	196.00
IUUC-Lpe-051424	Leersia perrieri	35.64	2.00e-92	332.00
IUUC-Loc-052105	Lepisosteus oculatus	56.52	8.00e-62	231.00
IUUC-Mor-056985	Magnaporthe oryzae	50.00	3.00e-52	199.00
IUUC-Mpo-057486	Magnaporthe poae	51.55	2.00e-53	204.00
IUUC-Mtr-058138	Medicago truncatula	53.50	1.00e-61	230.00
IUUC-Mla-058848	Melampsora laricipopulina	50.74	3.00e-55	209.00
IUUC-Mga-060162	Meleagris gallopavo	59.41	4.00e-70	258.00
IUUC-Mmr-061105	Microcebus murinus	58.88	3.00e-69	255.00
IUUC-Mdo-062107	Monodelphis domestica	59.39	1.00e-69	256.00
IUUC-Mac-064956	Musa acuminata	57.61	7.00e-64	237.00
IUUC-Nfi-068330	Neosartorya fischeri	44.12	2.00e-46	181.00
IUUC-Ncr-068879	Neurospora crassa	52.60	2.00e-53	204.00
IUUC-Ont-071834	Oreochromis niloticus	58.71	1.00e-70	260.00
IUUC-Ocu-074573	Oryctolagus cuniculus	58.88	2.00e-69	256.00
IUUC-Oba-075427	Oryza barthii	59.78	9.00e-63	233.00
IUUC-Obr-076902	Oryza brachyantha	59.24	6.00e-63	234.00
IUUC-Ogl-077583	Oryza glaberrima	49.75	2.00e-56	213.00
IUUC-Ogu-078422	Oryza glumaepatula	59.78	9.00e-63	233.00
IUUC-Oin-079453	Oryza indica	59.78	8.00e-63	234.00
IUUC-Olo-080315	Oryza longistaminata	60.33	3.00e-63	235.00
IUUC-Ome-081271	Oryza meridionalis	59.78	9.00e-63	234.00
IUUC-Oni-082834	Oryza nivara	59.78	1.00e-62	233.00
IUUC-Opu-083691	Oryza punctata	51.17	2.00e-58	219.00
IUUC-Oru-084820	Oryza rufipogon	59.78	1.00e-62	233.00
IUUC-Osa-086139	Oryza sativa	59.78	1.00e-62	233.00
IUUC-Olu-087717	Ostreococcus lucimarinus	52.02	5.00e-60	224.00
IUUC-Oga-088562	Otolemur garnettii	56.45	2.00e-62	233.00
IUUC-Oar-089767	Ovis aries	59.39	4.00e-70	258.00
IUUC-Pma-094533	Petromyzon marinus	58.29	1.00e-68	253.00
IUUC-Pno-094890	Phaeosphaeria nodorum	39.19	7.00e-43	168.00
IUUC-Ppa-095825	Physcomitrella patens	31.22	2.00e-20	94.00
IUUC-Pfo-097110	Poecilia formosa	58.67	4.00e-70	258.00
IUUC-Pop-099313	Populus trichocarpa	57.61	6.00e-61	228.00
IUUC-Ppe-101587	Prunus persica	59.24	2.00e-64	239.00
IUUC-Pgr-103546	Puccinia graminis	42.15	1.00e-52	201.00
IUUC-Ptt-103847	Puccinia triticina	47.30	5.00e-53	202.00
IUUC-Pte-104102	Pyrenophora teres	41.26	1.00e-44	174.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	41.70	7.00e-45	175.00
IUUC-Sce-106170	Saccharomyces cerevisiae	46.19	1.00e-46	181.00
IUUC-Sha-107393	Sarcophilus harrisii	59.39	9.00e-70	257.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	50.27	5.00e-54	204.00
IUUC-Smo-108686	Selaginella moellendorffii	36.96	9.00e-96	342.00
IUUC-Sit-109948	Setaria italica	34.51	8.00e-91	327.00
IUUC-Sly-111746	Solanum lycopersicum	55.50	2.00e-64	239.00
IUUC-Stu-112671	Solanum tuberosum	59.24	5.00e-64	238.00
IUUC-Sar-113542	Sorex araneus	57.21	1.00e-69	256.00
IUUC-Sbi-114874	Sorghum bicolor	56.00	7.00e-64	237.00
IUUC-Sre-115130	Sporisorium reilianum	52.53	7.00e-60	224.00
IUUC-Tgu-117267	Taeniopygia guttata	58.47	1.00e-66	246.00
IUUC-Tru-118298	Takifugu rubripes	59.18	2.00e-70	259.00
IUUC-Tni-120093	Tetraodon nigroviridis	59.18	2.00e-70	259.00
IUUC-Tca-121001	Theobroma cacao	57.58	6.00e-66	244.00
IUUC-Tre-121888	Trichoderma reesei	48.68	2.00e-50	193.00
IUUC-Tvi-122422	Trichoderma virens	44.14	2.00e-50	194.00
IUUC-Tae-125295	Triticum aestivum	34.87	8.00e-94	337.00
IUUC-Tur-126478	Triticum urartu	49.04	6.00e-58	218.00
IUUC-Tme-127062	Tuber melanosporum	51.05	3.00e-52	199.00
IUUC-Tbe-127672	Tupaia belangeri	58.88	1.00e-69	256.00
IUUC-Ttr-128441	Tursiops truncatus	58.88	1.00e-69	256.00
IUUC-Uma-129498	Ustilago maydis	51.06	1.00e-55	210.00
IUUC-Vda-129781	Verticillium dahliae	47.09	2.00e-51	197.00
IUUC-Vvi-131010	Vitis vinifera	35.61	3.00e-95	342.00
IUUC-Xma-133550	Xiphophorus maculatus	58.67	5.00e-70	258.00
IUUC-Yli-134392	Yarrowia lipolytica	46.41	4.00e-54	206.00
IUUC-Zma-135699	Zea mays	56.00	6.00e-64	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence