iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000014803.1	ENSORLT00000018559.1	ENSORLP00000018558.1
ENSORLG00000014803.1	ENSORLT00000018562.1	ENSORLP00000018561.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-99	332.7	60	388

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn++elr+++l+ + ++l+ +n   ++++l+++++kl ++lw + + +a+sp+++ + ++++a++f g +
   Q: 60   VGLRNLGNTCFMNSILQCLSNTSELRDYCLR-NVHRLDVNN--RTNAALMEEFAKLTQSLWtSVNIEAISPSDFRSEIQRVAPKFVGCN 145
           6******************************.777887775..599***************99999*********************** PP
   S: 89   qqDaqEflaflldqleeelkk...eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           qqDaqEfl+ lld+l++e+++   + ++++e++ + +++e+s+  ++    +++s ++dlF gqlks+++c  c+ +s+ ++pf+dls+
   Q: 146  QQDAQEFLRSLLDGLHNEVNRvtvRPRSSVEDFDHYSDEEKSKRMWNLYLAREDSKVVDLFVGQLKSSLTCTVCGFRSTMFDPFWDLSI 234
           *******************9955444455555566666777777999****************************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldls 262
           p+ +++   + +l+dcL+ ftke+ l+ge+k  c+kck++++++k+++++k+P++L++hLkRf  s ++++++k+++ v+fpl+ Ldl+
   Q: 235  PIAQERP-GEVTLKDCLRLFTKEDVLDGEEKPTCNKCKARRKCTKRFSIQKFPQILVIHLKRF--SDSNSRSSKLSTFVNFPLKeLDLR 320
           ****995.588****************************************************..77778999**********99**** PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           +f ++++    e+  Y+L+av +H+G++ +GHY+ay++n   + W+ ++Ds+V++++  +v +   s+aYvlfY+
   Q: 321  EFSADNS----EHPVYNLYAVSNHTGNTLGGHYTAYCRNPALGeWYSYNDSRVSPISSGQVRT---SNAYVLFYE 388
           ***9944....379*************************87767*******************...********8 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MPSLRHSYTV TVPEEPAAFP LDKPELRRKS QRFSRSVLVS TFMGLIINQA KYNKSPQGLV 60
GLRNLGNTCF MNSILQCLSN TSELRDYCLR NVHRLDVNNR TNAALMEEFA KLTQSLWTSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAACACCGC GCAGTTGTAC GCGCGTGACA GCAGCTTTCA CCCACGCAGC TGGTGGCTTT 60
TCCTTTGGCG TCACCACGAA GAGAAGACGA CACGCGTGAG AACTCCACAC CGATTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005132	Anolis carolinensis	69.57	3.00e-146	511.00
IUUC-Ame-011102	Astyanax mexicanus	77.33	1.00e-163	568.00
IUUC-Cin-025797	Ciona intestinalis	49.85	4.00e-96	344.00
IUUC-Dre-027476	Danio rerio	75.31	8.00e-164	569.00
IUUC-Dme-032208	Drosophila melanogaster	47.46	3.00e-78	286.00
IUUC-Gmo-039129	Gadus morhua	68.75	6.00e-147	513.00
IUUC-Gga-040889	Gallus gallus	66.57	1.00e-131	462.00
IUUC-Gac-042475	Gasterosteus aculeatus	84.25	0.00e+00	645.00
IUUC-Ont-071573	Oreochromis niloticus	83.63	0.00e+00	634.00
IUUC-Pfo-096602	Poecilia formosa	79.75	0.00e+00	645.00
IUUC-Pte-104348	Pyrenophora teres	31.72	3.00e-41	163.00
IUUC-Tru-117703	Takifugu rubripes	72.41	8.00e-159	552.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence