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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046478
UUCD1 version UUC-HoS-00591
Ensembl Protein ID ENSP00000274773.7
UniProt Accession Q9C029; A2RUE4; D3DWR7; Q969F5; Q96F67; Q96J89; Q96J90; TRIM7_HUMAN
Genbank Protein ID AAG53486.1; AAK85377.1; AAK85378.1; AAK85379.1; AAK85380.1; AAK85381.1; EAW53718.1; EAW53716.1; EAW53717.1; EAW53719.1; AAH11567.1; AAH80553.1; AAI32864.1; AAI32868.1
Protein Name Tripartite motif-containing protein 7; Glycogenin-interacting protein; RING finger protein 90
Genbank Nucleotide ID AF220032; AF396651; AF396652; AF396653; AF396654; AF396655; CH471165; CH471165; CH471165; CH471165; BC011567; BC080553; BC132863; BC132867
Gene Name TRIM7; GNIP; RNF90
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000146054.17 ENST00000274773.11 ENSP00000274773.7
ENSG00000146054.17 ENST00000393319.7 ENSP00000376994.3
ENSG00000146054.17 ENST00000334421.5 ENSP00000334666.5
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitemiRTarBasemicroRNA
TRANSFACTargetScanRepTarmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
DNA Methylation
MethyCancerTCGAICGCCOSMIC
Protein Expression/Proteomics
THPAGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.10e-06 30.2 27 96
E3 activity/RING/RING 4.40e-06 28.8 29 82
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlpsGitydrssIekwlasggk..............tcPvtrqplteedlvPnltl 61
             C+I lel+r+Pv +++G+++ r++I ++ ++ g                cP +r+p ++++l Pn  l
   Q: 27   ATCSICLELFREPVSVECGHSFCRACIGRCWERPGAgsvgaatrappfplPCPQCREPARPSQLRPNRQL 96
           67*****************************88877889999*************************987 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw..pglknssskefr........CPlCr 46
           C+iCle f++ p+++ CgH f++ C+  +w  p     s ++++        CP Cr
   Q: 29   CSICLELFRE-PVSVECGHSFCRACIgRCWerP--GAGSVGAATrappfplpCPQCR 82
           ********88.***************9999552..2223333335566667799997 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAAVGPRTGP GTGAEALALA AELQGEATCS ICLELFREPV SVECGHSFCR ACIGRCWERP 60
GAGSVGAATR APPFPLPCPQ CREPARPSQL RPNRQLAAVA TLLRRFSLPA AAPGEHGSQA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046478|E3,U-box;E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGTAGTCAA CGTGCGCCTC CCCTCCCGGC TCCCAGCCGG GCGCGCCCCG GGCTCGAGTC 60
TCTGCCTGCC CAGTGGCAGC CCCGCCCTTC CTCTCCCAGT GGGCCCTCGG CGCCCAGCTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046478|E3,U-box;E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF
SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
KEGG hsa:81786
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002208 Ailuropoda melanoleuca 77.65 1.00e-164 573.00
IUUC-Aca-004600 Anolis carolinensis 51.95 2.00e-127 449.00
IUUC-Bta-013412 Bos taurus 89.04 0.00e+00 786.00
IUUC-Cja-018837 Callithrix jacchus 80.51 0.00e+00 672.00
IUUC-Cfa-021142 Canis familiaris 85.14 0.00e+00 699.00
IUUC-Csa-023833 Chlorocebus sabaeus 96.29 0.00e+00 831.00
IUUC-Dno-029233 Dasypus novemcinctus 90.22 0.00e+00 763.00
IUUC-Dor-030639 Dipodomys ordii 75.63 2.00e-116 412.00
IUUC-Ete-032949 Echinops telfairi 75.82 9.00e-178 616.00
IUUC-Fca-035623 Felis catus 90.22 0.00e+00 801.00
IUUC-Fal-037164 Ficedula albicollis 53.88 4.00e-143 501.00
IUUC-Gga-040382 Gallus gallus 52.16 1.00e-144 506.00
IUUC-Gac-041608 Gasterosteus aculeatus 31.81 4.00e-62 232.00
IUUC-Ggo-044993 Gorilla gorilla 98.96 0.00e+00 866.00
IUUC-Itr-048378 Ictidomys tridecemlineatus 91.39 0.00e+00 808.00
IUUC-Mcc-054752 Macaca mulatta 97.26 0.00e+00 859.00
IUUC-Mga-059412 Meleagris gallopavo 48.89 2.00e-132 466.00
IUUC-Mvi-060296 Microbotryum violaceum 51.61 2.00e-05 44.70
IUUC-Mdo-062980 Monodelphis domestica 75.14 0.00e+00 725.00
IUUC-Mmu-063677 Mus musculus 89.43 0.00e+00 776.00
IUUC-Mpu-066023 Mustela putorius furo 88.85 0.00e+00 791.00
IUUC-Nle-069798 Nomascus leucogenys 93.74 0.00e+00 874.00
IUUC-Opr-071019 Ochotona princeps 83.56 0.00e+00 717.00
IUUC-Ocu-074797 Oryctolagus cuniculus 91.00 0.00e+00 841.00
IUUC-Oar-090169 Ovis aries 88.85 0.00e+00 782.00
IUUC-Ptr-091172 Pan troglodytes 97.85 0.00e+00 855.00
IUUC-Pan-092631 Papio anubis 97.65 0.00e+00 868.00
IUUC-Pab-098704 Pongo abelii 99.10 1.00e-152 532.00
IUUC-Pca-100337 Procavia capensis 93.18 3.00e-101 362.00
IUUC-Rno-105413 Rattus norvegicus 87.87 0.00e+00 787.00
IUUC-Sha-107360 Sarcophilus harrisii 65.71 1.00e-163 569.00
Created Date 25-Jun-2017

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