iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	4.60e-06	27.8	8	73

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 3    vilvvggeeffahkivLaas..SsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           + ++vgg+ f+++  +La +   s+F alf+ +++ s+  +   i+ + p++f +ll+ l+tg l+++
   Q: 8    IKFNVGGRIFETTATTLANAgrDSFFGALFDENWNLSQ-PGDLFID-RNPDCFAVLLDLLRTGDLNIP 73
           679**************98777***************9.*******.****************99875 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MGLSNDRIKF NVGGRIFETT ATTLANAGRD SFFGALFDEN WNLSQPGDLF IDRNPDCFAV 60
LLDLLRTGDL NIPPNIPERL LHKEAMFYGL IDHLRTAKWG PFDGNRLHLS RSVTGIAPGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGACCAAGA CAGATCGTTT TATTTTCTCT TCTGGGAATC TCAGCTTTTT TTAAAAAAAT 60
ATCCAGAGTC CAGATCATCG TATTCAATTT GATTAATCAT AAATCAGATT TCATTTCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

PROSITE

PS50097--BTB

Pfam

PF02214--BTB_2

SMART

SM00225--BTB

Gene Ontology

GO:0051260--P:protein homooligomerization
GO:0016567--P:protein ubiquitination

KEGG

ath:AT4G30940

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000385	Aegilops tauschii	33.33	3.00e-06	45.40
IUUC-Apl-003419	Anas platyrhynchos	37.50	2.00e-09	55.80
IUUC-Aca-004906	Anolis carolinensis	42.22	4.00e-10	59.70
IUUC-Acl-008201	Aspergillus clavatus	26.44	9.00e-02	30.80
IUUC-Afl-008739	Aspergillus flavus	26.87	2.00e-06	43.90
IUUC-Bci-013656	Botrytis cinerea	38.81	2.00e-05	41.60
IUUC-Cel-018212	Caenorhabditis elegans	42.22	6.00e-10	58.90
IUUC-Cja-019718	Callithrix jacchus	37.86	5.00e-10	57.80
IUUC-Cho-025009	Choloepus hoffmanni	37.86	1.00e-09	57.00
IUUC-Cin-025338	Ciona intestinalis	37.37	6.00e-08	51.20
IUUC-Csv-026147	Ciona savignyi	38.38	6.00e-11	61.20
IUUC-Cgl-026736	Colletotrichum gloeosporioides	37.88	3.00e-03	36.60
IUUC-Dor-031135	Dipodomys ordii	37.86	8.00e-10	57.40
IUUC-Ete-032730	Echinops telfairi	36.89	7.00e-09	53.90
IUUC-Eca-034291	Equus caballus	37.86	1.00e-09	56.60
IUUC-Eeu-034712	Erinaceus europaeus	37.86	1.00e-09	56.60
IUUC-Fal-037398	Ficedula albicollis	37.14	3.00e-09	55.50
IUUC-Gmo-039259	Gadus morhua	38.20	3.00e-10	57.80
IUUC-Gga-040956	Gallus gallus	37.86	1.00e-09	56.60
IUUC-Gma-042788	Glycine max	26.35	9.00e-19	87.40
IUUC-Hsa-046973	Homo sapiens	37.50	5.00e-10	58.20
IUUC-Itr-048735	Ictidomys tridecemlineatus	37.50	9.00e-10	57.40
IUUC-Lch-050356	Latimeria chalumnae	36.26	5.00e-09	53.90
IUUC-Mcc-054965	Macaca mulatta	37.50	5.00e-10	58.20
IUUC-Meu-056811	Macropus eugenii	36.56	4.00e-09	53.10
IUUC-Mtr-057875	Medicago truncatula	34.02	1.00e-05	43.10
IUUC-Mga-060041	Meleagris gallopavo	37.14	2.00e-09	55.80
IUUC-Mvi-060491	Microbotryum violaceum	31.25	8.60e+00	25.00
IUUC-Mmr-061291	Microcebus murinus	37.86	2.00e-09	56.60
IUUC-Mdo-062188	Monodelphis domestica	37.86	1.00e-09	57.00
IUUC-Mmu-063814	Mus musculus	37.50	1.00e-09	57.00
IUUC-Mac-065391	Musa acuminata	32.46	1.00e-07	49.70
IUUC-Mpu-066130	Mustela putorius furo	37.86	2.00e-09	56.60
IUUC-Nle-069467	Nomascus leucogenys	37.50	5.00e-10	58.20
IUUC-Ont-071375	Oreochromis niloticus	41.38	2.00e-09	57.00
IUUC-Oan-072912	Ornithorhynchus anatinus	37.86	1.00e-09	57.00
IUUC-Ocu-074232	Oryctolagus cuniculus	37.65	1.00e-07	51.20
IUUC-Ola-086979	Oryzias latipes	37.23	5.00e-10	58.20
IUUC-Oga-088456	Otolemur garnettii	38.83	3.00e-10	58.90
IUUC-Ptr-091495	Pan troglodytes	37.50	5.00e-10	58.20
IUUC-Psi-093745	Pelodiscus sinensis	36.79	1.00e-09	57.00
IUUC-Ppa-095251	Physcomitrella patens	34.48	2.00e-07	48.90
IUUC-Pab-098309	Pongo abelii	37.50	5.00e-10	58.20
IUUC-Pop-100014	Populus trichocarpa	33.33	2.00e-06	45.80
IUUC-Pca-100847	Procavia capensis	41.18	2.00e-08	53.50
IUUC-Pva-102420	Pteropus vampyrus	38.24	2.00e-09	55.80
IUUC-Rno-105486	Rattus norvegicus	37.50	1.00e-09	57.00
IUUC-Smo-109623	Selaginella moellendorffii	31.11	1.10e-02	33.90
IUUC-Sar-113407	Sorex araneus	37.86	1.00e-09	56.60
IUUC-Ssc-116381	Sus scrofa	36.79	2.00e-08	51.60
IUUC-Tgu-116844	Taeniopygia guttata	37.36	3.00e-09	54.70
IUUC-Tsy-119496	Tarsius syrichta	37.86	1.00e-09	56.60
IUUC-Tae-123780	Triticum aestivum	33.33	2.00e-06	45.40
IUUC-Tbe-128011	Tupaia belangeri	38.83	3.00e-10	58.90
IUUC-Vda-129852	Verticillium dahliae	36.07	7.00e-03	34.30
IUUC-Vpa-130047	Vicugna pacos	38.10	3.00e-05	43.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence