iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000019578.3	ENSXETT00000042340.2	ENSXETP00000042340.2
ENSXETG00000019578.3	ENSXETT00000062378.1	ENSXETP00000060789.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-18	64.3	780	832

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 780  IARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKG--ETNGRIGWFPSTYVEE 832
           678**********************************..9*************86 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MTEGWRQCGR WLIDCKVLPV DHRVVWPSAV VFDLAQALRD GVLLCQLLHN LSPGSIDLKD 60
INFRPQMSQF LCLKNIRTFL KVCHDKFGLR NCDLFDPFDL FDVRDFGKVI AALSKVSYHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCCTTGCC GGGCTTGCCA ACATGACCGA GGGTTGGCGG CAGTGCGGAC GCTGGCTCAT 60
AGACTGCAAA GTTCTCCCAG TGGACCACCG GGTCGTGTGG CCTTCTGCCG TGGTCTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	76.32	0.00e+00	1250.00
IUUC-Apl-003262	Anas platyrhynchos	78.37	0.00e+00	1341.00
IUUC-Ath-007352	Arabidopsis thaliana	40.00	2.00e-03	37.70
IUUC-Ame-011608	Astyanax mexicanus	75.47	0.00e+00	1336.00
IUUC-Bta-013147	Bos taurus	75.45	0.00e+00	1067.00
IUUC-Cel-018578	Caenorhabditis elegans	33.02	7.00e-77	282.00
IUUC-Cja-018877	Callithrix jacchus	74.85	0.00e+00	1180.00
IUUC-Cfa-020315	Canis familiaris	79.58	0.00e+00	1059.00
IUUC-Cpo-021543	Cavia porcellus	74.67	0.00e+00	1092.00
IUUC-Csa-024204	Chlorocebus sabaeus	75.81	0.00e+00	1335.00
IUUC-Cin-025115	Ciona intestinalis	36.52	3.00e-141	496.00
IUUC-Csv-025995	Ciona savignyi	37.11	2.00e-147	516.00
IUUC-Dre-028308	Danio rerio	73.55	0.00e+00	1313.00
IUUC-Dno-029584	Dasypus novemcinctus	75.69	0.00e+00	993.00
IUUC-Dor-031014	Dipodomys ordii	66.46	0.00e+00	999.00
IUUC-Eca-033448	Equus caballus	75.43	0.00e+00	1299.00
IUUC-Eeu-035182	Erinaceus europaeus	71.39	5.00e-163	567.00
IUUC-Fca-035460	Felis catus	76.72	0.00e+00	1117.00
IUUC-Fal-036684	Ficedula albicollis	76.60	0.00e+00	1337.00
IUUC-Gmo-038816	Gadus morhua	72.21	0.00e+00	1043.00
IUUC-Gga-040999	Gallus gallus	80.92	0.00e+00	1369.00
IUUC-Gac-041353	Gasterosteus aculeatus	73.39	0.00e+00	1091.00
IUUC-Ggo-044558	Gorilla gorilla	77.25	0.00e+00	1343.00
IUUC-Hsa-046208	Homo sapiens	77.36	0.00e+00	1345.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	76.25	0.00e+00	1028.00
IUUC-Loc-052827	Lepisosteus oculatus	73.86	0.00e+00	1324.00
IUUC-Laf-054009	Loxodonta africana	74.40	0.00e+00	1276.00
IUUC-Mcc-055054	Macaca mulatta	77.36	0.00e+00	1343.00
IUUC-Meu-056269	Macropus eugenii	72.83	0.00e+00	642.00
IUUC-Mga-060106	Meleagris gallopavo	78.83	0.00e+00	1351.00
IUUC-Mmr-061118	Microcebus murinus	77.56	0.00e+00	1343.00
IUUC-Mdo-062380	Monodelphis domestica	78.67	0.00e+00	1125.00
IUUC-Mmu-063135	Mus musculus	77.91	0.00e+00	1356.00
IUUC-Mpu-066135	Mustela putorius furo	78.24	0.00e+00	1234.00
IUUC-Nle-069465	Nomascus leucogenys	72.71	0.00e+00	1241.00
IUUC-Ont-071945	Oreochromis niloticus	73.58	0.00e+00	1285.00
IUUC-Oan-073384	Ornithorhynchus anatinus	74.03	0.00e+00	1033.00
IUUC-Ola-087499	Oryzias latipes	72.45	0.00e+00	1011.00
IUUC-Oga-088444	Otolemur garnettii	78.16	0.00e+00	1118.00
IUUC-Oar-089576	Ovis aries	73.25	0.00e+00	1026.00
IUUC-Ptr-090507	Pan troglodytes	78.25	0.00e+00	1352.00
IUUC-Pan-092325	Papio anubis	80.45	0.00e+00	1359.00
IUUC-Psi-094021	Pelodiscus sinensis	80.31	0.00e+00	1350.00
IUUC-Pma-094372	Petromyzon marinus	49.71	0.00e+00	650.00
IUUC-Pfo-096732	Poecilia formosa	73.58	0.00e+00	1293.00
IUUC-Pab-098426	Pongo abelii	66.79	0.00e+00	986.00
IUUC-Pca-100295	Procavia capensis	76.10	0.00e+00	1233.00
IUUC-Rno-105332	Rattus norvegicus	77.91	0.00e+00	1342.00
IUUC-Sha-106529	Sarcophilus harrisii	77.60	0.00e+00	1058.00
IUUC-Ssc-116176	Sus scrofa	75.15	0.00e+00	1202.00
IUUC-Tgu-116917	Taeniopygia guttata	77.21	0.00e+00	1225.00
IUUC-Tru-118398	Takifugu rubripes	72.29	0.00e+00	904.00
IUUC-Tni-120819	Tetraodon nigroviridis	71.26	0.00e+00	1094.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence